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Fentanyl - Spirit of Healing: Alberta First Nations Conquering
Fentanyl - Spirit of Healing: Alberta First Nations Conquering

... Opioids such as Fentanyl attach to receptors in the brain. When opiate drugs attach themselves to the body’s opioid receptors, they cause an increase in dopamine levels in the brain’s reward areas. Since dopamine is responsible for pleasure reward, attention, sleep, and mood, the body reacts by feel ...
Body System Adverse Effects
Body System Adverse Effects

... Mosby items and derived items © 2007, 2005, 2002 by Mosby, Inc., an affiliate of Elsevier Inc. ...
Cholecystokinin and GABA interaction in hippocampus in the
Cholecystokinin and GABA interaction in hippocampus in the

... Accepted Manuscript, Basic and Clinical Neuroscience (Volume XX, Number XX) claim, it has been shown that the analgesic, rewarding, and withdrawal-induced aversive effects of morphine are eliminated in mice disrupted for mu-opioid receptors (Matthes et al., 1996; Sora et al., 1997). The present res ...
Salvia divinorum and Salvinorin A: An Update on Pharmacology and
Salvia divinorum and Salvinorin A: An Update on Pharmacology and

... and the pharmacological profile studied in vitro are at jeopardy. A further study evaluated the effect of products of the in vitro autoxidation of salvinorin A. The main product of the neutral fraction after basic cleavage with 1 M KOH in methanol was an enedione. The major product in the base-solub ...
anesthetics
anesthetics

... eliminate pain response in 50% of patients ...
Hair Analysis for Cocaine: The Requirement for Effective Wash
Hair Analysis for Cocaine: The Requirement for Effective Wash

... Porosity among hair samples, most often increased by cosmetic treatments but also varying naturally among different hair types, has contributed greatly to confusion about binding of drugs to hair, as well as about contamination and washing issues. (27). Various theories and explanations of melanin b ...
Preclinical Evaluation of the Effects of a Novel Antisense Compound
Preclinical Evaluation of the Effects of a Novel Antisense Compound

... oligodeoxynucleotide which targets human C-raf kinase and is currently being developed as an antineoplastic agent. The toxicity of this compound was evaluated in mice and monkeys following repeated iv injections or infusions for 4 weeks at doses up to 100 mg/kg. Because CGP 69846A is inactive in the ...
t.5
t.5

... S.U.'s age and history of cardiac disease place him at higher risk for TCA toxicity than other patient. Therefore, he should started on the lowest available dose (10-25 mg/day). Even though these low doses are unlikely to result in a therapeutic response, concern for both the cardiovascular and othe ...
How to Protect Yourself Against Malaria
How to Protect Yourself Against Malaria

... struggle, within a few years the Anopheles had developed a resistance to these chemicals. Other pesticides followed, always with the same inglorious result. Today, many species of Anopheles have been reported resistant to traditional insecticides. The more recent insecticides, the carbamate compound ...
intravenous buprenorphine in humans
intravenous buprenorphine in humans

... slight decrease in respiratory rate, and subjective effects that included elevation in drug liking, good effects, and increases in the MBG scores. These actions are consistent with the suggestion that intravenous buprenorphine has substantial abuse potential. This suggestion is supported by worldwid ...
Psychotropics and Sudden Cardiac Death
Psychotropics and Sudden Cardiac Death

... syndrome, electrolyte abnormalities, polypharmacy and preexisting cardiac disease.1,13-15 For relatively healthy patients without preexisting risk factors, routine ECG monitoring should be considered for those with episodes of blackouts, fainting, seizures, or with unexplained lightheadedness, palpi ...
GINKGO BILOBA: A Cognitive Enhancer?
GINKGO BILOBA: A Cognitive Enhancer?

... than long-term, biological actions that provide the bases for any effects ginkgo has on cognition. This issue is very important for understanding the mechanisms by which ginkgo might act on cognitive functions and is also very important in defining the conditions under which ginkgo might be effectiv ...
CONSCIOUSNESS
CONSCIOUSNESS

... They include amphetamines, cocaine, MDMA (ecstasy), nicotine, and caffeine Stimulants can cause psychological and physically dependence ...
Rational Pharmacology
Rational Pharmacology

... plasma histamine concentration was 6 ng/ml. If emergency patients with upper GI bleeding then have a histamine release reaction either due to the endoscopy itself” or to any drugs that may be preoperatively given, their reactions may be more severe than in those patients undergoing elective surgery. ...
domperidone domperidone
domperidone domperidone

... In some cases of long-term domperidone treatment, leakage of milk and colostrum has occurred. If leakage should occur and foaling does not take place within 24 hours, half the recommended dose should be administered twice daily at approximately 12-hour intervals and continued until foaling. If leaka ...
PLEASE POST THIS SUMMARY IN AREAS WHERE MPTP IS USED
PLEASE POST THIS SUMMARY IN AREAS WHERE MPTP IS USED

... norepinephrine reuptake inhibitors, tricyclic antidepressants, other selegiline products, cocaine, local anesthesia containing sympathomimetic vasoconstrictors; increased risk of serious adverse effects, including serotonin syndrome concomitant use of sympathomimetic amines including amphetamines an ...
results - Pakistan Journal of Pharmaceutical Sciences
results - Pakistan Journal of Pharmaceutical Sciences

... significant at (P<0.05). This was supported by Al-Rekabi et al., 2009 who found significantly increased levels of ALP after inducing a 3 fold higher dose (0.6mg/kg) of meloxicam in rats. Similar observations were also reported by Mahaprabhu et al., 2011 who described significantly increased levels o ...
Marijuana as a Schedule I Substance: Political Ploy or Accepted
Marijuana as a Schedule I Substance: Political Ploy or Accepted

... does not result in a withdrawal syndrome with severe symptomatology."6 4 Dependence on the drug is more likely to be psychological than physical.6 5 b. Behavioral Effects Marijuana has sedative, euphoriant, and, when taken in large doses, hallucinogenic properties.66 At low to moderate doses, clinic ...
1 - The University of Liverpool Repository
1 - The University of Liverpool Repository

... falciparum, P. ovale, P. malariae, P. vivax and P. knowlesi). Disease in humans is initiated when an infected female Anopheles mosquito takes a blood meal during which infective forms of the parasite (named sporozoites) are injected into the blood stream (Figure 1).6 Within 15-30 minutes sporozoite ...
Pharmaceuticals: Focussing on Appropriate Utilization
Pharmaceuticals: Focussing on Appropriate Utilization

... drugs. The assumption is that, other than death and other catastrophic events like heart attack or hip fracture, we have few population-based measures of "effect" or outcomes from the consumption of pharmaceuticals. However, indicators of both utilization and appropriateness, which are antecedents o ...
CRS Newsletter. Volume 25, Number 2. 2008
CRS Newsletter. Volume 25, Number 2. 2008

... As part of the drive to improve the current situation, several initiatives have been set up to facilitate the growing demand for clinical research in the paediatric setting. Indeed, the World Health Organisation has recently launched a global campaign to “make medicines child size,” and several memb ...
Imitrex - GlaxoSmithKline
Imitrex - GlaxoSmithKline

... three of the subjects (two of whom also had chest pain/discomfort). Diagnostic angiogram results revealed that 9 subjects had normal coronary arteries and 1 had insignificant coronary artery disease. In an additional study with this same drug, migraine patients (n=35) free of cardiovascular disease ...
Bar or Bargad Ficus benghalensis L.
Bar or Bargad Ficus benghalensis L.

... included in prescription combinations of digestive enzymes to replace what individuals with cystic fibrosis or pancreas conditions cannot produce naturally. Because it improves digestion in general, papain has also been used orally to treat less serious digestion disorders such as bloating and chron ...
Deadly pediatric poisons: nine common agents that kill at low doses
Deadly pediatric poisons: nine common agents that kill at low doses

... any other age group [1]. According to data compiled by the American Association of Poison Control Centers (AAPCC), more than 1.3 million exposures involving children age 12 and younger were reported to poison control centers in 2001 [2]. Of these, more than 1 million (79%) involved children 3 years ...
How to Protect Yourself Against  Malaria
How to Protect Yourself Against Malaria

... struggle, within a few years the Anopheles had developed a resistance to these chemicals. Other pesticides followed, always with the same inglorious result. Today, many species of Anopheles have been reported resistant to traditional insecticides. The more recent insecticides, the carbamate compound ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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