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Protective Effects of Aqueous and Alcoholic Extracts of Piper longum
Protective Effects of Aqueous and Alcoholic Extracts of Piper longum

... safety of the anti-epileptic drugs has always been a concern. Herbal drugs may serve as the alternative for some such patients. Many plants have been used for the treatment of epilepsy in traditional system of medicines have shown useful anti-seizure activity. Herbal remedies have become popular, du ...
PDF - Journal of Applied Pharmaceutical Science
PDF - Journal of Applied Pharmaceutical Science

... anterior part of the nasal cavity, the nasal vestibule, opens to the face through the nostril. The nasal cavity consists three main regions are nasal vestibule, olfactory region and respiratory region. The surface area in the nose can be enlarges about 150cm by the lateral walls of the nasal cavity ...
Effect of grapefruit juice on bioavailability of montelukast
Effect of grapefruit juice on bioavailability of montelukast

... Initially developed as a treatment for asthma, montelukast has been increasingly accepted for many indications such as allergic rhinitis and chronic urticaria.4,12,13 Generally, montelukast is considered to be a safe drug. No clinically significant changes in vital signs, laboratory parameters, or E ...
Exercise and Neural Function Take Home Messages
Exercise and Neural Function Take Home Messages

... b. Treadmill running with no shock inducements can promote a training effect without stressful side effects 2. The exercise effect increasing passive avoidance memory was abolished by stimulating serotonin 5-HT1A receptors a. 8-OH-DPAT is a 5-HT1A agonist (also binds 5-HT7 receptors) b. Not related ...
Phosphodiesterase 5 inhibitors: are they cardioprotective?
Phosphodiesterase 5 inhibitors: are they cardioprotective?

MS Essentials 19
MS Essentials 19

... or with help from family or carers. Therapies like this are most effective when they are done regularly.4, 5 Always consult a health care professional before starting new exercise plans or trying out different therapies – it makes sense to know that a therapy will not be dangerous, or do more harm t ...
Heroin Add 10(3).indb - Addiction Treatment Forum
Heroin Add 10(3).indb - Addiction Treatment Forum

... However, as in the case we are about to discuss, sometimes new drugs must be introduced because of the improper use of older medications. 2. Pharmacotherapy of heroin addiction 2.1 The treatment of opiate addiction as de-conditioning from heroin reward with a need to concurrently stabilize and stimu ...
Full PDF - American Journal of Physiology
Full PDF - American Journal of Physiology

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enzyme induction and inhibition
enzyme induction and inhibition

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Ahead of print online version Moxidectin causes adult worm
Ahead of print online version Moxidectin causes adult worm

... Abstract: Moxidectin is a macrocyclic lactone belonging to milbemycin family closely related to ivermectin and is currently progressing towards Phase III clinical trial against human infection with the filaria Onchocerca volvulus (Leuckart, 1894). There is a single report on the microfilaricidal and ...
Product Monograph
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... In very rare cases, drugs with this effect on the ECG can lead to disturbances in heart rhythm (arrhythmias/dysrhythmias) that could result in dizziness, palpitations (sensation of rapid, pounding, or irregular heart beat), fainting or death. These heart rhythm disturbances are more likely in patien ...
METOPROLOL ACTAVIS
METOPROLOL ACTAVIS

... serum free thyroxine (T4) levels. In the absence of any signs or symptoms of hyperthyroidism, additional investigation is necessary before a diagnosis of thyrotoxicosis can be made. Other metabolic effects: Beta-adrenoceptors are involved in the regulation of lipid as well as carbohydrate metabolism ...
PERCOCET - Endo Pharmaceuticals
PERCOCET - Endo Pharmaceuticals

... Concomitant use of PERCOCET with CYP3A4 inducers or discontinuation of an CYP3A4 inhibitor could decrease PERCOCET plasma concentrations, decrease opioid efficacy or, possibly, lead to a withdrawal syndrome in a patient who had developed physical dependence to PERCOCET. When using PERCOCET with CYP ...
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IN VITRO MICROSPHERES

Discriminative Stimulus Properties of MDMA
Discriminative Stimulus Properties of MDMA

... MDMA using drug discrimination procedures in laboratory animals. Despite evidence that training dose can markedly impact the results of drug discrimination studies, the impact of training dose on the discriminative stimulus properties of MDMA has been largely overlooked. The broad aims of these expe ...
3 0 M a r c h 1 6 ,
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... open to the public for observation and participation. Anyone wishing to make an oral presentation should notify the contact person listed above 8s soon as possible before the meeting. The request should state the amount of time desired, the capacity in which the person will appear. and 8 brief outli ...
Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform
Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform

... of suppressed effects from heart failure, multiple organ dysfunction, and temperature. Various pathophysiological disturbances including hepatic ischemia and changes in hepatic blood flow may significantly alter the PK behavior of drugs. Therefore, a thorough understanding of both the temperature an ...
Prednisone - BC Children`s Hospital
Prednisone - BC Children`s Hospital

... Prednisone is a steroid which is very effective in reducing inflammation. It is used in many rheumatic diseases such Lupus, Juvenile Dermatomyositis, Linear Scleroderma, Juvenile Idiopathic Arthritis and Vasculitis. Prednisone is often used to achieve rapid improvement of a child’s disease, before o ...
Zantac™ Syrup Zantac™ Tablets
Zantac™ Syrup Zantac™ Tablets

... acquired pneumonia in current users of H2 receptor antagonists versus those who had stopped treatment, with an observed adjusted relative risk increase of 1.63 (95% CI, 1.07–2.48). Regular supervision of patients who are taking non-steroidal anti-inflammatory drugs concomitantly with ranitidine is r ...
Muscle spasms and stiffness
Muscle spasms and stiffness

... Living with spasms and stiffness can be frustrating for everyone involved, but understanding the issues can help everyone deal with them. This booklet might be helpful if you are explaining your symptoms to others, and anyone can call the MS Helpline (see page 19). Treatments are likely to work bett ...
HIV / AIDS
HIV / AIDS

... combinations of three or more to create an effective antiviral therapy. In addition, there are multiple investigational new drug applications (INDs) that have been submitted to the U.S. Food and Drug Administration to conduct clinical trials on HIV candidates. With approximately five million people ...
Homebrew equipoise 200mg/ml for Muscle Builing Boldenone
Homebrew equipoise 200mg/ml for Muscle Builing Boldenone

... The good news is that Boldenone undecylenate produces very little in the way of estrogen related side effects. In fact its actual rate of estrogen conversion is half that of the various testosterones. Of course some sensitive individuals may still experience estrogenic effects (or those using extrem ...
efficacy of Donepezil and Galantamine on retrograde amnesia
efficacy of Donepezil and Galantamine on retrograde amnesia

... manifest with transient neurological abnormalities and disturbances  in  higher  cognitive  functions,  particularly  learning  and  memory.14  Learning  and  memory  are,  inter  alia,  dependent  on  normal  cholinergic  neurotransmission;  the  relationship  may  be  dose‐ dependent.15  Electroco ...
Fentanyl - Spirit of Healing: Alberta First Nations Conquering
Fentanyl - Spirit of Healing: Alberta First Nations Conquering

... Opioids such as Fentanyl attach to receptors in the brain. When opiate drugs attach themselves to the body’s opioid receptors, they cause an increase in dopamine levels in the brain’s reward areas. Since dopamine is responsible for pleasure reward, attention, sleep, and mood, the body reacts by feel ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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