Case series of perimenopausal women with insomnia treated with
... develops over days to weeks (Luthringer et al. 2009; Wade et al. 2010, 2011). Interestingly, mirtazapine treatment has been reported to increase endogenous nocturnal melatonin in normal controls (Palazidou et al. 1989) and in depressed patients (Schmid et al. 2006). It is therefore likely that the b ...
... develops over days to weeks (Luthringer et al. 2009; Wade et al. 2010, 2011). Interestingly, mirtazapine treatment has been reported to increase endogenous nocturnal melatonin in normal controls (Palazidou et al. 1989) and in depressed patients (Schmid et al. 2006). It is therefore likely that the b ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... property and compared with aspirin. It is known that the NK1expressing neuron in lamina I to III of the spinal cord are associated with the perpetuation of pain after a peripheral injury and that these neurons can be selectively inhibited by the 5HT3antagonist ondansetron. Case report by Gary McClea ...
... property and compared with aspirin. It is known that the NK1expressing neuron in lamina I to III of the spinal cord are associated with the perpetuation of pain after a peripheral injury and that these neurons can be selectively inhibited by the 5HT3antagonist ondansetron. Case report by Gary McClea ...
08_opoids
... administration of certain opioids that release histamine (e.g., morphine) and do not represent a true allergy. Pruritus and erythema are often localized to the area of injection (e.g., along the vein through which the morphine was administered). Symptoms typically are controlled easily with antihist ...
... administration of certain opioids that release histamine (e.g., morphine) and do not represent a true allergy. Pruritus and erythema are often localized to the area of injection (e.g., along the vein through which the morphine was administered). Symptoms typically are controlled easily with antihist ...
Industrial Pharmacy II - Home|Faculty Members Websites|The
... to release the drug liquid fill matrix). Suckable softgels (gelatin shell contains flavoured medicament to be sucked and a liquid matrix or just air inside the capsule). Twist-off softgels (designed with a tag to be twisted or snipped off allowing access to the fill material, it is very useful f ...
... to release the drug liquid fill matrix). Suckable softgels (gelatin shell contains flavoured medicament to be sucked and a liquid matrix or just air inside the capsule). Twist-off softgels (designed with a tag to be twisted or snipped off allowing access to the fill material, it is very useful f ...
40 Complementary and Alternative Medical Treatment for Depression
... In the interest of safety and time efficacy of CAM therapies, emphasis has been placed on the need to hold CAM therapies to the same scientific standards as conventional medicine [18]. It is very important to characterize the possible toxicity of alternative therapies and to evaluate CAM compounds f ...
... In the interest of safety and time efficacy of CAM therapies, emphasis has been placed on the need to hold CAM therapies to the same scientific standards as conventional medicine [18]. It is very important to characterize the possible toxicity of alternative therapies and to evaluate CAM compounds f ...
Influence of weather conditions, drugs and
... Drug history and defined daily doses Drugs with the alleged potential to increase or decrease sodium and/ or chloride were recorded: thiazides (6 generic substances), loop diuretics (2), K-sparing diuretics (3), carboanhydrase inhibitors (1), angiotensin-converting enzyme inhibitors (ACEIs; 12), angi ...
... Drug history and defined daily doses Drugs with the alleged potential to increase or decrease sodium and/ or chloride were recorded: thiazides (6 generic substances), loop diuretics (2), K-sparing diuretics (3), carboanhydrase inhibitors (1), angiotensin-converting enzyme inhibitors (ACEIs; 12), angi ...
GASTRO-RETENTIVE DRUG DELIVERY SYSTEM CONTENTS
... the gastric contents without affecting the intrinsic rate of emptying because their bulk density is lower than that of the gastric contents. Many results have demonstrated the validity of the concept of buoyancy in terms of prolonged GRT of the floating forms, improved bioavailability of drugs and i ...
... the gastric contents without affecting the intrinsic rate of emptying because their bulk density is lower than that of the gastric contents. Many results have demonstrated the validity of the concept of buoyancy in terms of prolonged GRT of the floating forms, improved bioavailability of drugs and i ...
In Vitro and In Vivo Evaluation of Microparticulate Drug
... features. Doxorubicin (DOX) is a strong antitumor agent, but shows severe toxic side effects such as cardiac toxicity, which limits its clinical use. Various macromolecular prodrugs of DOX have been developed. Conjugates of DOX with HPMA and carboxymethyl-dextran (CM-Dextran) linked via biodegradabl ...
... features. Doxorubicin (DOX) is a strong antitumor agent, but shows severe toxic side effects such as cardiac toxicity, which limits its clinical use. Various macromolecular prodrugs of DOX have been developed. Conjugates of DOX with HPMA and carboxymethyl-dextran (CM-Dextran) linked via biodegradabl ...
Basics Pharmacology Review - Dr. Roland Halil
... • Understand the pharmacological classes, generic examples and mechanisms of action of important tools in the practice of medicine. • Understand how the pharmaco-kinetics and dynamics of these agents can affect their use • Highlight clinical pearls in the proper use of these agents in practice. ...
... • Understand the pharmacological classes, generic examples and mechanisms of action of important tools in the practice of medicine. • Understand how the pharmaco-kinetics and dynamics of these agents can affect their use • Highlight clinical pearls in the proper use of these agents in practice. ...
Post Tonsillectomy Pain Introduction
... vomiting, and pain in pediatric tonsillectomy A single I.V. injection of DEX at the induction of anesthesia was effective in reducing the incidence of early and late PONV and the level of pain on the second postoperative day. A 0.15 mg/ kg DEX dose appeared to be as effective as a 0.5 mg /kg dose to ...
... vomiting, and pain in pediatric tonsillectomy A single I.V. injection of DEX at the induction of anesthesia was effective in reducing the incidence of early and late PONV and the level of pain on the second postoperative day. A 0.15 mg/ kg DEX dose appeared to be as effective as a 0.5 mg /kg dose to ...
development and in vitro evaluation of buccoadhesive tablets
... Buccoadhesion, or the attachment of a natural or synthetic polymer to a biological substrate, is a practical method of drug immobilization or localization and an important new aspect of controlled drug delivery. The unique environment of the oral (buccal) cavity offers its potential as a site for dr ...
... Buccoadhesion, or the attachment of a natural or synthetic polymer to a biological substrate, is a practical method of drug immobilization or localization and an important new aspect of controlled drug delivery. The unique environment of the oral (buccal) cavity offers its potential as a site for dr ...
Notes on Some Immunosuppressive Agents and Their Use in
... first liver transplant patients on this regimen, the cyclophosphamide was continued for 9 months. More recently, the protocol has been adjusted in that cyclophosphamide is now given only for the first 1 to 2 months, following which a change is made to azathioprine. The rationale for such a successiv ...
... first liver transplant patients on this regimen, the cyclophosphamide was continued for 9 months. More recently, the protocol has been adjusted in that cyclophosphamide is now given only for the first 1 to 2 months, following which a change is made to azathioprine. The rationale for such a successiv ...
STANDARD vs. MODIFIED RELEASE STANDARD vs. MODIFIED
... asymmetric twice-daily dosing for the prophylactic treatment of angina. What about tolerance? Some degree of nitrate tolerance is observed after chronic dosing with any nitrate preparation.1,2 The most important issue when prescribing nitrates is to use a dosing strategy which protects against ischa ...
... asymmetric twice-daily dosing for the prophylactic treatment of angina. What about tolerance? Some degree of nitrate tolerance is observed after chronic dosing with any nitrate preparation.1,2 The most important issue when prescribing nitrates is to use a dosing strategy which protects against ischa ...
Sections 11 to 17
... The WHO Expert Committee on Use of Essential Drugs recognizes the value of lipid-lowering drugs in treating patients with hyperlipidaemia. HMG-CoA reductase inhibitors, often referred to as "statins", are a family of potent and effective lipid-lowering drugs with a good tolerability profile. Several ...
... The WHO Expert Committee on Use of Essential Drugs recognizes the value of lipid-lowering drugs in treating patients with hyperlipidaemia. HMG-CoA reductase inhibitors, often referred to as "statins", are a family of potent and effective lipid-lowering drugs with a good tolerability profile. Several ...
Jane Stewart`s CV - Concordia University
... Stewart, J., Vallentyne, S., & Meaney, M.J. Differential effects of testosterone metabolites in the neonatal period on open-‐field behavior and lordosis in the rat. Hormones and Behavior, 1979, 13, 282- ...
... Stewart, J., Vallentyne, S., & Meaney, M.J. Differential effects of testosterone metabolites in the neonatal period on open-‐field behavior and lordosis in the rat. Hormones and Behavior, 1979, 13, 282- ...
OTC pain management guidelines - South African Pharmacist`s
... Ibuprofen, naproxen and other NSAIDs are considered therapeutically equivalent, although a particular individual may respond better to one agent than another.2, 7 NSAIDS vary in how quickly they work and how long they relieve pain.2 Ibuprofen and naproxen are better tolerated than aspirin as they ca ...
... Ibuprofen, naproxen and other NSAIDs are considered therapeutically equivalent, although a particular individual may respond better to one agent than another.2, 7 NSAIDS vary in how quickly they work and how long they relieve pain.2 Ibuprofen and naproxen are better tolerated than aspirin as they ca ...
A COMPARATIVE STUDY OF THE EFFECT OF ONDANSETRON
... 2009). The commonly used classes of drugs for the treatment of anxiety are benzodiazepines, azapirones, selective serotonin reuptake inhibitors (SSRIs) and beta blockers (Eisendrath SJ, 2009). The benzodiazepines are the drugs of choice for the treatment of generalized anxiety as they provide immedi ...
... 2009). The commonly used classes of drugs for the treatment of anxiety are benzodiazepines, azapirones, selective serotonin reuptake inhibitors (SSRIs) and beta blockers (Eisendrath SJ, 2009). The benzodiazepines are the drugs of choice for the treatment of generalized anxiety as they provide immedi ...
Targeting Microtubules by Natural Agents for Cancer Therapy
... Mitosis phase facilitates the equal partitioning of replicated chromosomes into two identical groups. The success of this process requires highly dynamic microtubules in the spindle (1, 8, 9). Microtubule dynamics are critical for the timely and correct attachment of chromosomes at their kinetochore ...
... Mitosis phase facilitates the equal partitioning of replicated chromosomes into two identical groups. The success of this process requires highly dynamic microtubules in the spindle (1, 8, 9). Microtubule dynamics are critical for the timely and correct attachment of chromosomes at their kinetochore ...
Intracellular Modulation of NMDA Receptor Function by
... which the rats were treated with antipsychotic drugs. For chronic treatment paradigms of rats, see Table 1. In the acute treatment paradigm, rats were killed 40 min after antipsychotic drug treatment for RNA analysis, and 2 hr after antipsychotic drug treatment for protein analysis (immunocytochemis ...
... which the rats were treated with antipsychotic drugs. For chronic treatment paradigms of rats, see Table 1. In the acute treatment paradigm, rats were killed 40 min after antipsychotic drug treatment for RNA analysis, and 2 hr after antipsychotic drug treatment for protein analysis (immunocytochemis ...
rajiv gandhi university of health sciences, bangalore
... from the adrenergic stimulation of the SA node; this response is generally quite modest except when the drug is administered rapidly. Indeed, the concurrent use of a receptor antagonist drug may magnify negative chronotropic effects of these drugs or cause heart block in susceptible patients.9 The p ...
... from the adrenergic stimulation of the SA node; this response is generally quite modest except when the drug is administered rapidly. Indeed, the concurrent use of a receptor antagonist drug may magnify negative chronotropic effects of these drugs or cause heart block in susceptible patients.9 The p ...
Edi Schwager
... The major neural systems affected by amphetamine are largely implicated in the brain’s reward circuitry. Moreover, neurotransmitters involved in various reward pathways of the brain appear to be the primary targets of amphetamine.[32] One such neurotransmitter is dopamine, a chemical messenger heavi ...
... The major neural systems affected by amphetamine are largely implicated in the brain’s reward circuitry. Moreover, neurotransmitters involved in various reward pathways of the brain appear to be the primary targets of amphetamine.[32] One such neurotransmitter is dopamine, a chemical messenger heavi ...
MATRICARIA EXTRACT IN MICE RECUTITA
... The data of the present study showed that pretreatment of animals with Matricaria extract significantly increase both the latency and onset of seizure induced by strychnine as well as dampened the severity of tonic convulsion compared to untreated control animals. These results suggested the protect ...
... The data of the present study showed that pretreatment of animals with Matricaria extract significantly increase both the latency and onset of seizure induced by strychnine as well as dampened the severity of tonic convulsion compared to untreated control animals. These results suggested the protect ...
Review of Antibody-Drug Conjugates, Methods in Molecular Biology
... organic synthesis with biotechnological processing. As a result, a series of new and unique engineering and chemistry challenges must be addressed to support clinical trials and commercial manufacturing. These include the development of reliable processes leading to uniform product properties, as we ...
... organic synthesis with biotechnological processing. As a result, a series of new and unique engineering and chemistry challenges must be addressed to support clinical trials and commercial manufacturing. These include the development of reliable processes leading to uniform product properties, as we ...
The Use of Melengestrol Acetate (MGA) in Cattle Feed and the
... Despite a wealth of research examining the safety of MGA and other steroidal growth promoters use in food animals, the subject is still up for debate. Unfortunately, this contentious issue is further clouded by a lack of understanding from the general public, whose beliefs are often based on anecdot ...
... Despite a wealth of research examining the safety of MGA and other steroidal growth promoters use in food animals, the subject is still up for debate. Unfortunately, this contentious issue is further clouded by a lack of understanding from the general public, whose beliefs are often based on anecdot ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.