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Prof Moosa - Meningitis in HIV Diagnostic
Prof Moosa - Meningitis in HIV Diagnostic

... Send at least 6/8mls CSF for proper microbiology evaluation Imaging is mainly of value in evaluating for complications and exclude alternate diagnosis Rifampicin can only be used with LVP/r and not any other PI. Drug of choice with any other PI is rifabutin ...
Chemical Restraint of African Lions (Panthera leo) with
Chemical Restraint of African Lions (Panthera leo) with

click here
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... From Day 3 to Day 4 Postpartum ...
article in press
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... that nearly two-thirds of PD patients reported sleep disturbances, which is significantly more frequently than patient with diabetes and healthy control subjects [34]. Furthermore, about a third of PD patients rated their overall nighttime problems as moderate to severe. Virtually all patients with ...
Ocular Side Effects of Sildenafil: A Prospective Study
Ocular Side Effects of Sildenafil: A Prospective Study

... hemorrhages.4 However, a recent study found that there is “lack of conclusive evidence to indicate a direct causeeffect relationship between phosphodiesterase enzyme type 5 (PDE5) inhibitor use and vision-threatening ocular events. Men who use PDE5 inhibitors appear to suffer vision-threatening comp ...
Inhibition of Prostaglandin Synthesis and Effects of Ethanol and
Inhibition of Prostaglandin Synthesis and Effects of Ethanol and

... mg/kg) or placebo with a large glass of water (480 ml). One hour later, they swallowed capsules that contained pentobarbital (1.33 or 4 mg/kg) or placebo and a large drink (500 ml) of tonic water that contained ethanol (1 g/kg) or placebo (tonic water with 2 ml of ethanol floated on top) that was co ...
μ-Opioid Receptor-Mediated Depression of the Hypothalamic
μ-Opioid Receptor-Mediated Depression of the Hypothalamic

... opiates such as morphine inhibited the hypocretin system by direct actions on the cell body that include reduced spike frequency, hyperpolarization, increased G-protein-coupled inwardly rectifying K ⫹ channel current, and attenuated calcium current, and indirectly through reducing excitatory synapti ...
Brand Name - KVECBlindandVI
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Choosing a Skeletal Muscle Relaxant

... meta-analysis evaluated 14 studies comparing cyclobenzaprine with placebo for back and neck pain.27 The trials included were of less than 14 days’ duration. Cyclobenzaprine was found to be moderately more effective than placebo, but had more central nervous system adverse effects. The authors also d ...
Chapter 16 Cholinesterase Inhibitors
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... in Europe [6]. Indeed, the proportionate share of the total global burden of disease due to neurologic disorders is projected to rise to 14.7% by 2020 [7], highlighting an urgent need for more drugs to treat CNS disorders. ...
No Slide Title
No Slide Title

... •diarrhea, nausea, abnormal liver tests •acute attacks of gout •rash ...
Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures Zheng Zhou
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... for oral administration, available as extended-release tablets. NDA 19-962 /S-032 Page 4 Clinical pharmacology studies have confirmed the beta-blocking activity of metoprolol in man, as shown by (1) reduction in heart rate and. Learn about Lopressor (Metoprolol Tartrate) may treat, uses, dosage, sid ...
Oral Extended Release Drug Delivery System: A Promising Approach
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... single dose Extended release formulation is an important program for new drug research and development to meet several unmet clinical needs. There are several reasons for attractiveness of these dosage forms viz. provides increase bioavailability of drug product, reduction in the frequency of admini ...
Chapter 14 Marijuana
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... imparted while under the influence of marijuana In limited surveys, from 60% to 80% of marijuana user indicate that they sometimes drive while high. In a study conducted in the Boston area, marijuana smokers were overrepresented in fatal highway ...
complete IDD M Pharm Syllabus
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... while not fully awake after ingestion of a sedative-hypnotic, with amnesia for the event) have been reported with sedative-hypnotics, including zolpidem. These events can occur in sedative-hypnotic-naive as well as in sedative-hypnotic-experienced persons. Although behaviors such as "sleep-driving" ...
Formulation of Effervescent Ibuprofen
Formulation of Effervescent Ibuprofen

... This research is a formulation of the drug Ibuprofen as an effervescent tablet by two methods (direct compression and wet granulation). The bitter taste was masked by saccharine as sweeting agent with guargum and Tragacanth gum, furthermore the effervescent effect of citric acid, tartaric acid and s ...
Bacterial Growth Kinetics of "M. lufu" in the Presence and Absence
Bacterial Growth Kinetics of "M. lufu" in the Presence and Absence

... then be determined by the relation between its concentration and the related decrease in generation rate. Before evaluating the effect of drug combinations to discriminate between their possible additive, synergistic or antagonistic action, the inhibitory power of the single drugs was determined. Th ...
Saving Lives- A Case for Stocking Narcan in our School Health Offices
Saving Lives- A Case for Stocking Narcan in our School Health Offices

... Source: Registry of Vital Records and Statistics, MDPH 2014 ...
Transdermal Fentanyl
Transdermal Fentanyl

... • Place patches on non‐irradiated, hairless skin. If needed, clip hair, don’t shave, as shaving can cause  micro abrasions which may affect drug absorption. If site needs to be washed, do so with clear water;  soaps, lotions, alcohols and other agents can also affect drug absorption.  • With the rec ...
Adrenergic-Blocking Drugs
Adrenergic-Blocking Drugs

... prevent or minimize postural hypotension Avoid caffeine (excessive irritability) Avoid alcohol ingestion and hazardous activities until blood levels become stable Patients should notify their physician if palpitations, dyspnea, nausea, or vomiting occurs ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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