A treasure of medicinal herb - Anacyclus pyrethrum A review
... methylurea in a dose-dependent manner (Sukumaran & Kuttan, 1995). Antidepressant activity Badhe et al. (2010) previously determined antidepressant activity. Suicidal tendency remains one of the common outcomes of depression, with depressive illness being responsible for 60% of the death toll (Stahl, ...
... methylurea in a dose-dependent manner (Sukumaran & Kuttan, 1995). Antidepressant activity Badhe et al. (2010) previously determined antidepressant activity. Suicidal tendency remains one of the common outcomes of depression, with depressive illness being responsible for 60% of the death toll (Stahl, ...
Research and Development at Sun Pharma
... Key Features of technology developed Can produce controlled particle size for facile injection through conventional needle to reduce patient trauma and pain No local anaesthetic required while delivering the drug Closed semi-automatic process to give kilogram scale, reproducible, consistent and ...
... Key Features of technology developed Can produce controlled particle size for facile injection through conventional needle to reduce patient trauma and pain No local anaesthetic required while delivering the drug Closed semi-automatic process to give kilogram scale, reproducible, consistent and ...
Developing an Animal Model of Polysubstance Abuse in Adolescence
... of cocaine. What differed between the age groups were the aversive properties of ethanol, with adolescents being less sensitive to the aversive properties of ethanol and its modulating effects on cocaine reward. A role for the NAcc NMDA receptors was observed in contributing to the modulating effect ...
... of cocaine. What differed between the age groups were the aversive properties of ethanol, with adolescents being less sensitive to the aversive properties of ethanol and its modulating effects on cocaine reward. A role for the NAcc NMDA receptors was observed in contributing to the modulating effect ...
Herbal remedies and anticoagulant therapy Review Article Noah Samuels
... to hundreds of herbs which, with increasing likelihood, they will eventually purchase and use. Much research is still required to understand both the in vitro and, more importantly, in vivo effects of herbs on the pharmacodynamics of medications such as warfarin. For example, Ginkgo biloba extract w ...
... to hundreds of herbs which, with increasing likelihood, they will eventually purchase and use. Much research is still required to understand both the in vitro and, more importantly, in vivo effects of herbs on the pharmacodynamics of medications such as warfarin. For example, Ginkgo biloba extract w ...
Lipid-regulators (Agents Used in Hyperlipidemia)
... • Indications: High LDL • Uses: be used to relieve pruritis(瘙痒症) in patients who have cholestasis and bile salt accumulation; and/or to relieve diarrhea in post-cholecystectomy(胆囊切除术后) patients ...
... • Indications: High LDL • Uses: be used to relieve pruritis(瘙痒症) in patients who have cholestasis and bile salt accumulation; and/or to relieve diarrhea in post-cholecystectomy(胆囊切除术后) patients ...
Research and Development at Sun Pharma
... Key Features of technology developed Can produce controlled particle size for facile injection through conventional needle to reduce patient trauma and pain No local anaesthetic required while delivering the drug Closed semi-automatic process to give kilogram scale, reproducible, consistent and ...
... Key Features of technology developed Can produce controlled particle size for facile injection through conventional needle to reduce patient trauma and pain No local anaesthetic required while delivering the drug Closed semi-automatic process to give kilogram scale, reproducible, consistent and ...
Glucocorticoids
... Kansas State University Manhattan, KS Glucocorticoids Prednisone is a commonly used glucocorticoid. Prednisone is a pro-drug, therefore it must be metabolized to prednisolone to elicit its pharmacologic effect. Cats are variable metabolizers of prednisone to prednisolone, so the effect will also be ...
... Kansas State University Manhattan, KS Glucocorticoids Prednisone is a commonly used glucocorticoid. Prednisone is a pro-drug, therefore it must be metabolized to prednisolone to elicit its pharmacologic effect. Cats are variable metabolizers of prednisone to prednisolone, so the effect will also be ...
ACUTE PAIN MANAGEMENT
... Acetaminophen has fewer GI and renal adverse effects than NSAIDs. The maximum recommended daily dose for adults is 4 g. ✓ Hepatic toxicity has been associated with acute acetaminophen overdose as well as with usual doses in certain highrisk conditions or situations (eg, alcohol ingestion, cachexia o ...
... Acetaminophen has fewer GI and renal adverse effects than NSAIDs. The maximum recommended daily dose for adults is 4 g. ✓ Hepatic toxicity has been associated with acute acetaminophen overdose as well as with usual doses in certain highrisk conditions or situations (eg, alcohol ingestion, cachexia o ...
JAP Mar. 86/3 - Journal of Applied Physiology
... ANTITUSSIVE DRUGS, such as codeine and dextromethorphan, are among the most commonly used prescription and over-the-counter drugs in the world (12). These drugs are broadly classified into two groups based on their site of action: peripheral or central. Peripheral antitussive drugs act outside the c ...
... ANTITUSSIVE DRUGS, such as codeine and dextromethorphan, are among the most commonly used prescription and over-the-counter drugs in the world (12). These drugs are broadly classified into two groups based on their site of action: peripheral or central. Peripheral antitussive drugs act outside the c ...
Antithyroid Drugs
... Many retrospective studies clearly show that patients with more severe degrees of hyperthyroidism, large goiters, or a high triiodothyronine-tothyroxine ratio in the serum (when unitless, more than 20) are less likely to enter remission after a course of drug treatment than are those with milder dis ...
... Many retrospective studies clearly show that patients with more severe degrees of hyperthyroidism, large goiters, or a high triiodothyronine-tothyroxine ratio in the serum (when unitless, more than 20) are less likely to enter remission after a course of drug treatment than are those with milder dis ...
Research and Development at Sun Pharma
... Key Features of technology developed Can produce controlled particle size for facile injection through conventional needle to reduce patient trauma and pain No local anaesthetic required while delivering the drug Closed semi-automatic process to give kilogram scale, reproducible, consistent and ...
... Key Features of technology developed Can produce controlled particle size for facile injection through conventional needle to reduce patient trauma and pain No local anaesthetic required while delivering the drug Closed semi-automatic process to give kilogram scale, reproducible, consistent and ...
simultaneous estimation of salbutamol and ketotifen in tablet dosage
... Salbutamol (SAL) is chemically RS-[4-[2-(tert-butylamino)-1hydroxyethyl]-2-(hydroxymethyl) phenol] is a shortacting β2-adrenergic receptor agonist used for the relief of Bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease[1-3]. Salbutamol is still commonly delivered a ...
... Salbutamol (SAL) is chemically RS-[4-[2-(tert-butylamino)-1hydroxyethyl]-2-(hydroxymethyl) phenol] is a shortacting β2-adrenergic receptor agonist used for the relief of Bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease[1-3]. Salbutamol is still commonly delivered a ...
Basics Pharmacology Review - Dr. Roland Halil
... • List the four steps of rational prescribing • Understand the pharmacological classes, generic examples and mechanisms of action of important tools in the practice of medicine. • Understand how the pharmaco-kinetics and dynamics of these agents can affect their use • Highlight clinical pearls in th ...
... • List the four steps of rational prescribing • Understand the pharmacological classes, generic examples and mechanisms of action of important tools in the practice of medicine. • Understand how the pharmaco-kinetics and dynamics of these agents can affect their use • Highlight clinical pearls in th ...
CYNODON DACTYLON CATALEPSY Research Article
... The present study was done to evaluate the role of Cynodon dactylon, a plant traditionally used for parkinson’s disease, for its effect against reserpine induced catalepsy. Reserpine-induced catalepsy is a widely accepted animal model of Parkinson's disease40. Some authors have demonstrated that res ...
... The present study was done to evaluate the role of Cynodon dactylon, a plant traditionally used for parkinson’s disease, for its effect against reserpine induced catalepsy. Reserpine-induced catalepsy is a widely accepted animal model of Parkinson's disease40. Some authors have demonstrated that res ...
An evaluation of the histological effects of intra
... Discussion Canines, aged 1.5 to 4 years, weighing 20 to 23 kg were used for this study because they mimic the age at which anterior cruciate ligament reconstruction is generally done in humans and because the knee joint space can accommodate a 5-mL injectate. Additionally, the canines’ immune mechan ...
... Discussion Canines, aged 1.5 to 4 years, weighing 20 to 23 kg were used for this study because they mimic the age at which anterior cruciate ligament reconstruction is generally done in humans and because the knee joint space can accommodate a 5-mL injectate. Additionally, the canines’ immune mechan ...
PDF Format - Indian Pediatrics
... side effects and toxicity(DIG trial)(5). In a post hoc analysis of DIG trial, higher serum digoxin levels were associated with increased mortality in men with heart failure(6). Scant data exist for digoxin therapy in children with heart failure. Utility of digoxin in heart failure secondary to volum ...
... side effects and toxicity(DIG trial)(5). In a post hoc analysis of DIG trial, higher serum digoxin levels were associated with increased mortality in men with heart failure(6). Scant data exist for digoxin therapy in children with heart failure. Utility of digoxin in heart failure secondary to volum ...
Immediate time course of drug effect
... it illustrates a very simple principle -- “If the dose of a drug is doubled then the duration of response will increase by one half-life.” The duration of response means the time that the drug effect is above a predefined critical value e.g. the time above 50% of Emax. With a low dose (blue lines) t ...
... it illustrates a very simple principle -- “If the dose of a drug is doubled then the duration of response will increase by one half-life.” The duration of response means the time that the drug effect is above a predefined critical value e.g. the time above 50% of Emax. With a low dose (blue lines) t ...
Shared care available
... Hypersalivation which may be treated with Botulinum toxin Drug induced hallucinations become more common Patients can also develop cognitive impairment, drug induced confusion and increasing falls Mechanisms causing deterioration are unclear but may include nigral cell death, cortical involvem ...
... Hypersalivation which may be treated with Botulinum toxin Drug induced hallucinations become more common Patients can also develop cognitive impairment, drug induced confusion and increasing falls Mechanisms causing deterioration are unclear but may include nigral cell death, cortical involvem ...
Field Guide to Herbal Dietary Supplements
... of each ingredient or proprietary blend. Claims that are made on a product’s label or labeling are strictly controlled, must be substantiated, and must not claim to diagnose, treat, cure, or prevent any disease (even if there is evidence to support such a “drug claim”). Facilities in which herbal an ...
... of each ingredient or proprietary blend. Claims that are made on a product’s label or labeling are strictly controlled, must be substantiated, and must not claim to diagnose, treat, cure, or prevent any disease (even if there is evidence to support such a “drug claim”). Facilities in which herbal an ...
Central nervous system effects of caffeine and adenosine on fatigue
... protocol. By allowing this small variation in treadmill speed, overall run time to fatigue was much more consistent at ⬃90 min. 284 • FEBRUARY 2003 • ...
... protocol. By allowing this small variation in treadmill speed, overall run time to fatigue was much more consistent at ⬃90 min. 284 • FEBRUARY 2003 • ...
Biomarkers: An indispensible addition to the
... eventually inactivated in the body by the UGT1A1 enzyme. In 2005, the US Food and Drug Administration added a warning to the label of the drug, stating that patients homozygous for a particular a version of the UGT1A1 gene — the UGT1A1*28 allele, associated with decreased UGT1A1 enzyme activity — sh ...
... eventually inactivated in the body by the UGT1A1 enzyme. In 2005, the US Food and Drug Administration added a warning to the label of the drug, stating that patients homozygous for a particular a version of the UGT1A1 gene — the UGT1A1*28 allele, associated with decreased UGT1A1 enzyme activity — sh ...
Prolonged Attenuation of the Reinforcing Strength of
... evening PR sessions until responding stabilized (3 consecutive days on which the number of injections was within 2 of the 3-day mean, with no upward or downward trend). Subsequently, other doses of cocaine were substituted for the maintenance dose for at least 4 days and until the number of injectio ...
... evening PR sessions until responding stabilized (3 consecutive days on which the number of injections was within 2 of the 3-day mean, with no upward or downward trend). Subsequently, other doses of cocaine were substituted for the maintenance dose for at least 4 days and until the number of injectio ...
Grapefruit Seed Extract
... our seed extract falls below the range associated with bergamottin-mediated events, but is within the range of DHBassociated drug interactions. The negligible bergamottin suggests this extract does not recapitulate completely the negative effects of grapefruit juice and should be regarded as a disti ...
... our seed extract falls below the range associated with bergamottin-mediated events, but is within the range of DHBassociated drug interactions. The negligible bergamottin suggests this extract does not recapitulate completely the negative effects of grapefruit juice and should be regarded as a disti ...
Document
... Baseline mean ± SD (range): 29.2 ± 10.2 (14–57) Week 5 mean ± SD (range): 29.5 ± 9.0 (15–47) Mean difference: −0.3; 95% CI, −3.4 to 2.8 ...
... Baseline mean ± SD (range): 29.2 ± 10.2 (14–57) Week 5 mean ± SD (range): 29.5 ± 9.0 (15–47) Mean difference: −0.3; 95% CI, −3.4 to 2.8 ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.