Doc - World Noni Research Foundation
... in the extracts of Noni fruits. Looking to all parameters that were envisaged to study the herbal plant, Morinda citrifolia (Noni), it can be concluded that both aqueous and alcoholic extracts of Noni fruit contain several phytochemicals viz., alkaloid, amino acid, reducing sugar, glycosides, tannin ...
... in the extracts of Noni fruits. Looking to all parameters that were envisaged to study the herbal plant, Morinda citrifolia (Noni), it can be concluded that both aqueous and alcoholic extracts of Noni fruit contain several phytochemicals viz., alkaloid, amino acid, reducing sugar, glycosides, tannin ...
Reviews Essential Tremor - Tremor and Other Hyperkinetic
... the same drug, making the correlation between MOA and tremor reduction difficult (Table 1). For example, topiramate, which improves tremor, has at least five possible MOA that could theoretically affect tremor. Furthermore, only a minority of AED drugs have been studied specifically for tremor in we ...
... the same drug, making the correlation between MOA and tremor reduction difficult (Table 1). For example, topiramate, which improves tremor, has at least five possible MOA that could theoretically affect tremor. Furthermore, only a minority of AED drugs have been studied specifically for tremor in we ...
Ouabain - the insulin of the heart - Herzinfarkt
... symptoms and slow the progression of contractile dysfunction. Despite these therapeutic advances, heart failure is still associated with an annual morta]jty rate of 10% (1). The search for better treatments and optimisation of existing ones remain major challenges in cardiology. Modulation of myocar ...
... symptoms and slow the progression of contractile dysfunction. Despite these therapeutic advances, heart failure is still associated with an annual morta]jty rate of 10% (1). The search for better treatments and optimisation of existing ones remain major challenges in cardiology. Modulation of myocar ...
Oxytocin (Oxt) /ˌɒksɨˈtoʊsɪn/ is a mammalian neurohypophysial
... Recent studies have begun to investigate oxytocin's role in various behaviors, including orgasm, social recognition, pair bonding, anxiety, and maternal behaviors. For this reason, it is sometimes referred to as the "love hormone". There is some evidence that oxytocin promotes ethnocentric behavior, ...
... Recent studies have begun to investigate oxytocin's role in various behaviors, including orgasm, social recognition, pair bonding, anxiety, and maternal behaviors. For this reason, it is sometimes referred to as the "love hormone". There is some evidence that oxytocin promotes ethnocentric behavior, ...
Biobehavioral effects of baclofen in anxious alcohol
... The study visits/procedures were performed in consecutive phases as outlined in Figure 1. In-person screen. Baseline characteristics as well as the data needed to assess the eligibility criteria were collected. Baseline/randomization visit. After having a verified breath alcohol concentration (BrAC) ...
... The study visits/procedures were performed in consecutive phases as outlined in Figure 1. In-person screen. Baseline characteristics as well as the data needed to assess the eligibility criteria were collected. Baseline/randomization visit. After having a verified breath alcohol concentration (BrAC) ...
SDZ HTF 919 Stimulates Canine Colonic Motility and Transit In Vivo
... with the 0.03 and 0.3 mg/kg doses, but the large variability in the 0.1 mg/kg group reduced the significance of the overall drug effects. The similarity of gastric emptying with 0.03 and 0.3 mg/kg suggested that there was no dose-related effect of the agent. Effects of SDZ HTF 919 on colonic transit ...
... with the 0.03 and 0.3 mg/kg doses, but the large variability in the 0.1 mg/kg group reduced the significance of the overall drug effects. The similarity of gastric emptying with 0.03 and 0.3 mg/kg suggested that there was no dose-related effect of the agent. Effects of SDZ HTF 919 on colonic transit ...
Angina pectoris and Calcium Channel Blockers
... short acting (emphasis added) Ca channel blockers, especially in high doses, and particularly when combined with diuretics, was associated with an increased risk of myocardial infarction. (None of the therapies monitored decreased MI risk significantly) Cochrane, different result with long acting CE ...
... short acting (emphasis added) Ca channel blockers, especially in high doses, and particularly when combined with diuretics, was associated with an increased risk of myocardial infarction. (None of the therapies monitored decreased MI risk significantly) Cochrane, different result with long acting CE ...
Chapter 18 - The RedZone
... Used to support the heart during cardiac failure or shock; various alpha and beta ...
... Used to support the heart during cardiac failure or shock; various alpha and beta ...
A New Look at the 5α-Reductase Inhibitor Finasteride
... these fluctuations can contribute to diverse disorders such as premenstrual and postpartum dysphoric disorder (37), catamenial epilepsy (68), depression (148), and alcohol withdrawal (118). The inverse relationship between endogenous 3á,5á-THP levels and anxiety, depression and seizure susceptibilit ...
... these fluctuations can contribute to diverse disorders such as premenstrual and postpartum dysphoric disorder (37), catamenial epilepsy (68), depression (148), and alcohol withdrawal (118). The inverse relationship between endogenous 3á,5á-THP levels and anxiety, depression and seizure susceptibilit ...
Oleo-gum-resin of Ferula asafoetida: A traditional culinary spice with
... (GWM) contents of the stomach also supported these results, as these factors showed protection of various indices and replenishing the depleted (GWM) level by the suspension treatment, respectively. Authors discussed it is not well know that which chemical constituents of asafoetida are accountable ...
... (GWM) contents of the stomach also supported these results, as these factors showed protection of various indices and replenishing the depleted (GWM) level by the suspension treatment, respectively. Authors discussed it is not well know that which chemical constituents of asafoetida are accountable ...
Role for epithelial Na channels and putative Na /H
... µM concentrations of amiloride and benzamil are strong and unselective in their site of antagonism (see below). Furthermore, the mechanism of how amiloride is able to suppress NH4Cl responses also remains unknown. Prior studies in kidney medulla microsomes (16), chick skeletal muscle cells (30), and ...
... µM concentrations of amiloride and benzamil are strong and unselective in their site of antagonism (see below). Furthermore, the mechanism of how amiloride is able to suppress NH4Cl responses also remains unknown. Prior studies in kidney medulla microsomes (16), chick skeletal muscle cells (30), and ...
neuroregulatory effects of nicotine
... Nicotine acts on a select group of receptors centrally, and receptor interactions appear to be quite specific, resembling those of few other compounds. The exceptions are alkaloidal analogs such as cytisine and anabasine and the chemical stereo-isomers, 3-methyl-pyrridyl-pyrolidine and (+)nicotine ( ...
... Nicotine acts on a select group of receptors centrally, and receptor interactions appear to be quite specific, resembling those of few other compounds. The exceptions are alkaloidal analogs such as cytisine and anabasine and the chemical stereo-isomers, 3-methyl-pyrridyl-pyrolidine and (+)nicotine ( ...
Evaluation of Diuretic activities of hydro
... The kidneys receive about a quarter of the cardiac output. From the several hundred litres of plasma that flow through them each day, they filter (in a 70-kg human) approximately 120 litres per day, 11 times the total extracellular fluid volume. This filtrate is similar to plasma apart from the abs ...
... The kidneys receive about a quarter of the cardiac output. From the several hundred litres of plasma that flow through them each day, they filter (in a 70-kg human) approximately 120 litres per day, 11 times the total extracellular fluid volume. This filtrate is similar to plasma apart from the abs ...
Arrhythmia/Electrophysiology
... disease, including arrhythmia, coronary heart disease, and chronic heart failure. Activation of presynaptic ␣2adrenoceptors is the most widely accepted mechanism of action of the antisympathetic drug clonidine; however, other target proteins have been postulated to contribute to the in vivo actions ...
... disease, including arrhythmia, coronary heart disease, and chronic heart failure. Activation of presynaptic ␣2adrenoceptors is the most widely accepted mechanism of action of the antisympathetic drug clonidine; however, other target proteins have been postulated to contribute to the in vivo actions ...
University of Groningen The a-typical effects of olanzapine on body
... predominantly adipose tissue, may be related to a decreased level of physical activity (the sedative effect of Olanzapine), or by an increase in food intake, although again contradictory results have been found [21-23]. Furthermore, Olanzapine has also been shown to induce hypothermia [24] and to bl ...
... predominantly adipose tissue, may be related to a decreased level of physical activity (the sedative effect of Olanzapine), or by an increase in food intake, although again contradictory results have been found [21-23]. Furthermore, Olanzapine has also been shown to induce hypothermia [24] and to bl ...
PHARM4515-16 (NSAIDs)
... contains two aromatic ring systems that are perpendicular and not coplanar ...
... contains two aromatic ring systems that are perpendicular and not coplanar ...
Cocaine Is Self-Administered into the Shell but Not the Core of the
... Downloaded from jpet.aspetjournals.org at ASPET Journals on May 4, 2017 ...
... Downloaded from jpet.aspetjournals.org at ASPET Journals on May 4, 2017 ...
Actions of bufalin and cinobufotalin, two bufadienolides respectively
... As a result of this brief study it was decided to carry out all experimental studies on ouabain binding with incubation for 2 h. The results of the ouabain-sensitive binding assays with the addition of non-labelled ouabain, bufalin and cinobufotalin are shown in Fig. 1.All nine blood samples were te ...
... As a result of this brief study it was decided to carry out all experimental studies on ouabain binding with incubation for 2 h. The results of the ouabain-sensitive binding assays with the addition of non-labelled ouabain, bufalin and cinobufotalin are shown in Fig. 1.All nine blood samples were te ...
Chapter 07: Anticholinergic (Parasympatholytic) Bronchodilators
... Quaternary ammonium compounds are effective when inhaled (e.g., Atrovent®). Generally, quaternary ammonium compounds do not cross lipid membranes easily and do not distribute throughout the body when inhaled. Atrovent® is used frequently in respiratory care. REF: p. 127 8. Ipratropium bromide is ind ...
... Quaternary ammonium compounds are effective when inhaled (e.g., Atrovent®). Generally, quaternary ammonium compounds do not cross lipid membranes easily and do not distribute throughout the body when inhaled. Atrovent® is used frequently in respiratory care. REF: p. 127 8. Ipratropium bromide is ind ...
Comparison of Inhaled Corticosteroids: An Update
... these studies also provide results that vary between laboratories.15,16 The relative binding affinities correlate with relative potencies in carefully controlled clinical trials.17 It is clear from the relative potencies that some drugs (beclomethasone dipropionate, ciclesonide) act as prodrugs and ...
... these studies also provide results that vary between laboratories.15,16 The relative binding affinities correlate with relative potencies in carefully controlled clinical trials.17 It is clear from the relative potencies that some drugs (beclomethasone dipropionate, ciclesonide) act as prodrugs and ...
PDF
... researchers, anhedonia has a putative neural substrate, the dopaminergic mesolimbic and mesocortical reward circuit, which involves the ventral tegmental area (VTA), the ventral striatum, and part of the prefrontal cortex (Markou and Koob, 1991; Heinz et al., 1994; Isella et al., 2003; Willner et al ...
... researchers, anhedonia has a putative neural substrate, the dopaminergic mesolimbic and mesocortical reward circuit, which involves the ventral tegmental area (VTA), the ventral striatum, and part of the prefrontal cortex (Markou and Koob, 1991; Heinz et al., 1994; Isella et al., 2003; Willner et al ...
The Role of Corticotropin-Releasing Factor in Drug Addiction
... that are heterogenously distributed in both brain and peripheral tissues across species. In mammals, the two known native peptide agonists are CRF itself (also abbreviated CRH for corticotropin-releasing hormone) and urocortin. Presently, there are five distinct targets for CRF and urocortin with un ...
... that are heterogenously distributed in both brain and peripheral tissues across species. In mammals, the two known native peptide agonists are CRF itself (also abbreviated CRH for corticotropin-releasing hormone) and urocortin. Presently, there are five distinct targets for CRF and urocortin with un ...
Pain Therapeutics - Drugs, Markets and Companies Brochure
... Most of the currently used analgesic drugs fall into the categories of opioids and nonsteroidal antiinflammatory drugs such as COX-2 inhibitors. Non-opioid analgesics include ketamine, a N-methyl-Daspartate receptor antagonist. Adjuvant analgesics include antidepressants and antiepileptic drugs used ...
... Most of the currently used analgesic drugs fall into the categories of opioids and nonsteroidal antiinflammatory drugs such as COX-2 inhibitors. Non-opioid analgesics include ketamine, a N-methyl-Daspartate receptor antagonist. Adjuvant analgesics include antidepressants and antiepileptic drugs used ...