Download Medical Biochemistry. Human Metabolism in Health and Disease Brochure

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Medical Biochemistry. Human Metabolism in Health and Disease
Description:
Helps Readers Understand The Link Between Metabolic Pathways And Human Health And Disease
Medical Biochemistry enables readers to master the essentials of human metabolism by explaining how
metabolic pathways and reactions are connected to human health and disease. Rather than cover all the
reactions that human cells and tissues are capable of executing, this text better enables readers to learn
core concepts by emphasizing select examples that illustrate the physiologic and pathophysiologic
significance of the major metabolic pathways. Designed for medical, dental, and allied health students and
professionals, the text emphasizes clinically relevant information, helping readers understand the
interrelationships between metabolic pathways and the links between metabolism and the causes,
preventions, and cures for human diseases.
A separate chapter is dedicated to each of the key metabolic pathways that constitute human metabolism.
Each chapter features a six–part structure that facilitates a clear understanding of the metabolic processes:
Major function(s) of the pathway
Tissues in which the pathway is active
Physiological conditions under which the pathway is most active
Reactions that comprise the pathway
Regulation of the pathway
Examples of human diseases related to the pathway
Throughout the text, simple figures help readers understand how metabolic pathways and reactions work.
This text's concise, easy–to–follow approach helps readers understand and appreciate the functions,
constituent reactions, and regulatory aspects of the core pathways that constitute human metabolism and
are responsible for maintaining homeostasis and well–being in humans.
Contents:
PREFACE vii
ACKNOWLEDGMENTS ix
THE AUTHORS xi
1 INTRODUCTION TO METABOLISM 1
2 ENZYMES 11
3 DIGESTION AND ABSORPTION 38
4 GLYCOLYSIS 58
5 PYRUVATE DEHYDROGENASE AND THE TRICARBOXYLIC ACID CYCLE 77
6 ELECTRON TRANSPORT AND OXIDATIVE PHOSPHORYLATION 89
7 THE PENTOSE PHOSPHATE PATHWAY 102
8 GLYCOGEN 112
9 GLUCONEOGENESIS 126
10 FATTY ACID OXIDATION AND KETONES 141
11 FATTY ACID SYNTHESIS 162
12 TRIACYLGLYCEROL TRANSPORT AND METABOLISM 177
13 ETHANOL 191
14 PHOSPHOLIPIDS AND SPHINGOLIPIDS 199
15 EICOSANOIDS 218
16 GLYCOLIPIDS AND GLYCOPROTEINS 231
17 CHOLESTEROL SYNTHESIS AND TRANSPORT 246
18 STEROIDS AND BILE ACIDS 271
19 NITROGEN HOMEOSTASIS 290
20 AMINO ACIDS 305
21 SULFUR AMINO ACID METABOLISM 325
22 FOLATE AND VITAMIN B12 IN ONE–CARBON METABOLISM 335
23 PURINES AND PYRIMIDINES 351
24 HEME AND IRON 372
25 INTEGRATION OF METABOLISM 393
INDEX 411
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