Download 2010 (TeAMS)

TeAMS Embryo Exam 2010
1. The choroid plexus develops in all locations except:
a) LATERAL VENTRICLES
b) 3RD VENTRICLE
c) Aqueduct of Sylvius
d) 4TH VENTRICLE
2-4 Match the following:
a. Growth factor
b. Transcription Factor
c. Cell membrane protein
2. FGF 8- a
3. Brachyoryl T - b
4. E- Candherin – c
5. Which of the following is a myogenic transcription factor?
)aSHH
)bMyf5
)cMyt5
)dOtx3
6. Sensory epithelium of the skin is derived from?
a) Surface ectoderm
b) Neuroectoderm
c) Neural crest cells
7. Which factor determines if the development of the brain will turn into midbrain or
forebrain?
)aSHH
)bBMP4
)cHox
)dFoxG1 – Otx2
8. All of the following are examples of genomic imprinting except?
)aAngelman Syndrome
)bPrader Willi Syndrome
)cHydatidiform Mole
)dPlacenta Previa
9. Which of the following structures closes first?
a) Ductus venosus
b) Ductus arteriosus
c) Foramen ovale
d) IVC
10. Which of the following structures come in contact with maternal blood?
a. synctiotrophoblast
b. cytotrophoblast
c. endothelium
d. chorion
11. What's the source of the cilliary body?
.apars ceca (retina
.bpars optica retinae
.cintraretinal space
ahal ohs td a .21woman two to three months before she gets pregnant in order to
avoid birth defects?
A. Folic acid
13. What happens in pulmonary valve atresia?
A, Left atrium is smaller
b. ductus arteriosus remains patent
c. Very narrow aorta
d. Closed ductus areriosus
14. Which Congenital Disease is another name for "Caudal Dysgenesis:?
A. Amelia
B. Meromelia
C. Phocomelia
D. Micromelia
E. none of the above
15. Which one is formed last?
a. Primitive Streak
b. Trophoblast
d. Epiblast
e. Hypoblast
16. The allantois forms from a fold in the:
a. Endoderm
b. Mesoderm
c. Ectoderm
d. Exoderm
17. Which of the following is derived from the primitive node?
a. Notocord
18. Where are the 4 colliculi both superior and inferior developed from?
a. dorsal mesencephalon
19. How many Cotydelins in mature placenta at birth?
a. 5-10
b. 15-20
c. 60-80
d. 100-150
20. Connexins are found in:
a. SAMS
b. CJMs (cell junction molecules)
c. CAMS
d. TAM or JAM
21. Which of the following can cause incomplete closure between the 2 ventricles?
a. incomplete closure of muscular septum
b. incomplete closure of membranous septum
c. both - possible
d. neither
22. Which of the following is/are true about aqueous humor?
a. circulates from posterior to anterior chamber of the eye
b. It supplies avascular tissue of eye
c. It enters the blood circulation
d. flows through sinus sclera
e. all of the above
23. Loss of the SRY gene changes the response all of the following except?
a. sertoli cells
b. leydig cells
c. mullerian ducts and its derivatives
d. descent of the testicles
e. external sexual organs
24. All of the following can result from a defect in shh except?
a. cyclops,
b. abnormal finger development - ?
c. abnormal finger development - ?
d. Increase in motor neurons
25. All of following are part of the urinary collecting system except?
a. renal pelvis
b. minor and major calyces
c. ureter
d. ureteric bud
e. distal convoluted tubule
26. Picture of the embryo with a,b,c,d and asked which structure ends up most lateral
upon formation of body wall (don't remember the actual choices)
a. notocord
b. lateral mesoderm
c. somite c
27. Forelimbs usually form at somite 16 where HOX C6 works there and posterior. What
happens if HOX C6 starts acting only at somite 18 and posterior?
a. limb will stop developing
b. limb will develop at someite 18
c. Limb will develop normally
28. On the primitive streak, a green drop is placed anterior (closer to node) than a red
drop… later?
a. the green drop will be found more medial
29. Where is the location of the spiral ligament?
Ligament which connects to the lateral wall of cochlear duct
30. What is the embryological origin of the secondary palate?
a. first brachial arch
b. second brachial arch
c. premaxilla
d. first pharyngeal pouch
e. first pharyngeal cleft
31-36 Match the following (timing of events) In that same part they asked about
400
2
36
74
28
22
31. Time in days need for a whole cycle of spermiogenesis? 74
32. How many days is a womens menstrual cycle? 28
33. How many millions of primary oocytes that exist at birth? 2
34. How many hundreds of thousands of primary oocytes at puberty? 400
35. Time in days which primary spermatocytes exist in prophase of the first meiotic
division? 22
36. Time in hours from peak of LH surge until the start of ovulation? 36
37. The process of sprouting occurs during...
a. Spermatogenesis
b. Vasculogenesis
c. Angiogenesis
d. Oogenesis
38. Thyroglossal cysts are most likely to be found where? (really dont remember the
options)
a. behind hyoid bone
b. parathyroid?
c. thyroid??
d. something in the region of the mandible or maxillary bone?
39. Which doesn't form from the diencephalon?
a. cerebellum
b. optic vesicles
c. thalamus
d. hypothalamus
40. The embryological origin of bony skeleton of the face is
a. Paraxial mesoderm
b. Intermediate mesoderm
c. Endoderm
d. Lateral plate mesoderm
e. Neural crest (Neuroectoderm)
41. Which of the following tubes develop last?
a. gut tube
b. single heart tube
c. neural tube
d. Notocord
42. If a bead containing nodal protein is placed on right side of an embryo after the beginning of
gastrulation, what do you expect to see?
b. left isomerism
43. The defect in which layers of the brain AND ventricles fall out of the skull is called?
a. meningocele
b. meningoencephalocele
c. meningohydroencephalocele
44) Normal target motor neuron is the biceps muscle in the arm. If biceps muscle precursor cells are
removed before the axon of the motor neuron has begun to extend from neural tube, what most likely
happens to the motor neuron?
a. motor neuron will die
b. It will extend toward the bicep but stops growing,
c. It will continue growing without direction
d. the axon of the motor neuron will enter forelimb and reach place where biceps was supposed to be
and will then make connection with the closest muscle
45. CSF drainage occurs in which?
a. second ventricle
b. third ventricle
c. fourth ventricle
d. first ventricle
46. All influence the development of muscles in the ventral lateral lip (VLL) except
a. Shh
b. FGF's
c. MyoD
d. Wnt
47. Ureteric bud penetrates into:
a. Metanephric blastoma
48. Inner ridge of spiral limbus
a. Epithelial cells derived from collecting duct bind to tectorial membrane
49. Epaxial muscles are Innervated by dorsal primary rami
50. Question about isomerism
a. Right isomerism
b. Left isomerism
c. Situs inversus
d. Situs solitus
51. what/where is the inner ridge located
52. Another name for the anchoring villi of placenta?
a. secondary villi
b. stem villi
c. terminal villi
53. Question about where are the suspensory ligaments in the ear
54. Ventricular septal defects are usually result of problems in development of
a) membranous portion of Interventrcular septum
b) muscular portion of Interventrivular septum
c) both A and B
d) neither A or B are correct
55. something about a forelimb vs a hindlimb and dont remember if it was Shh or AER or
Tbx usually induces hindlimbs posteriorly, but if placed where forelimb is, what
happens? --> a leg at the arm position, an arm more posterior, an arm more anterior,
no limb grows,...
56. All of the following are derived from mesoderm except
a. Hepatocytes of the liver
57. Which statement is true about straited muscle
a. Myoblasts fuse to form multinucleated muscle
58. All of the following are true regarding AD PKD – Autosomal Dominant Polycystic Kidney Disease
except:
a. There is more frequent involvement of the left kidney than the right kidney
b. There can be elevated blood pressure
c. There can be aneurisms in blood vessels
d. There can be cysts in the liver, pancreas, prostate
e. Approximately 50% of patients develop end stage renal failure by the age of 60
59. Which is NOT a consequence of Mullerian duct anomaly
a. Uterus myomatosus
b. Uterus bicornis
c. Uterus didelphis
d. Uterus spetatum
60. In the defect Pulmonary Valvular Atresia, one finds
the foramen ovale remains open
61. Lining of external auditory meatus is derived from
Ectoderm
62. The origin of the Internal Brachial Fistula is
Cervical sinus
63. The 2nd, 3rd, and 4th pharyngeal arches
Fuse with epicardial ridge to form smooth neck
Leave behind an epithelial lined space, the cervical sinus
Fuse with remains of the first brachial arch
All of the above
64. Primary lens fibers
Are derived of surface ectoderm
65. Which statement is incorrect
Enchondral ossification occurs in sutures and fontanelles after birth
66. The discrepancy between size of newborn face and size of neurocranium attribute to
Small jaw size
Absence of paranasal
…
All of the above
67. Scaphoucephaly anomaly includes
Early closure of sagittal suture, skull shape: long and narrow
68. Which statement is true
Upper limbs rotate 90 degrees laterally, lower limbs rotate 90 degrees medially
69. in a strong loss-of-function mutant of Lmx1, you might see all the following problems in the
development of the hand except:
d. loss of fingerprints
70. the cardiac defect double outlet right ventricle occurs because:
c. the aortic outflow tract does not move sufficiently leftwards to make proper contact with left
ventricle
71. which tissues does not contain a component derived from the neural crest?
b. the occipital bone of the skull
72. which of the following is not correct?
d. the proximal-distal axis of limb is regulated by a Hox gene gradient
73. the first neurons to differentiate in the cerebral cortex are found in:
b. inner cortical plate
74. a woman is taking acutane for acne. the active ingredient in it is retinoic acid. if she becomes pregnant
while taking the drug, which can happen to the heart of her fetus?
a. loss of ventricle tissue
7. if remove AER from forelimb bud and replaced it with AER from a hindlimb bud, what do you expect
to happen?
b. forelimb continues to grow and develop normally