Download Pharmacology II - 4-12

Pharmacology Tutoring for
Drugs of Abuse
By Alaina Darby
[email protected]
Which of the following defines addiction?
a. Tolerance to the substance
b.Withdrawal syndrome
c. Compulsive drug use
d.Withdrawal symptoms relieved with
readministration
Which of the following functions as the “brake” for
other pathways in the brain and becomes weakened
with continued exposure to drugs?
a. VTA
b.Frontal cortex
c. Striatum
d.Nucleus accumbens
Which of the following is involved in motivated
behavior?
a. VTA
b.Frontal cortex
c. Striatum
d.Nucleus accumbens
Which of the following people are more likely to
experience addiction?
a. Prior experience with drugs
b.Slower drug metabolism
c. Underdeveloped frontal cortex
d.Innate tolerance
Which of the following is an environmental factor that
could discourage addiction?
a. Drug paraphanalia
b.Peer pressure
c. Employment
d.Psychiatric symptoms
Which of the following categories would you classify
the following scenario into: someone who learns to
walk a straight line while drunk?
a. Behavioral learned tolerance
b.Conditioned learned tolerance
c. Innate tolerance
d.Acute tolerance
Which of the following is the primary psychoactive
ingredient in marijuana?
a. Cannabidiol
b.Cannabinol
c. Tetrahydrocannabinol
d.Cannabigerol
Which of the following is associated with early stages
of a marijuana high?
a. Relaxation
b.Introspective
c. Depersonalization
d.Difficulty thinking
Which of the following is most indicative of acute
marijuana use as opposed to chronic use?
a. Decreased concentration
b.Apathy
c. Increased hunger
d.Decreased judgement
Which of the following is a hallmark sign of THC use?
a. Increased heart rate
b.Immunosuppression
c. CNS depression
d.Endocrine effects
Which of the following is a hormone that is not
decreased by marijuana use?
a. Luteinizing hormone
b.Follicle-stimulating hormone
c. Growth hormone
d.Adrenocorticotropin hormone
For which of the following conditions would smoking
marijuana help with initially but not if used
chronically?
a. Asthma
b.Diabetes
c. Heart disease
d.Obesity
Which of the following is not a function of 2aracidonylglycerol?
a. Neuroprotection
b.Suppress aversive memories
c. Depress food intake
d.Inhibit muscle contraction
In which of the following brain regions are
cannabinoid receptors least concentrated?
a. Central gray
b.Hippocampus
c. Cerebellum
d.Basal ganglia
Which of the following is the most potent and active?
a. Δ9-THC
b.11-Hydroxy-Δ9-THC
c. 8-Hydroxy-Δ9-THC
d.11-nor-Δ9-THC-9-carboxylic acid
Which of the following is the main metabolite that is
excreted?
a. Δ9-THC
b.11-Hydroxy-Δ9-THC
c. 8-Hydroxy-Δ9-THC
d.11-nor-Δ9-THC-9-carboxylic acid
Which of the following is not true of marijuana
tolerance?
a. Caused by inhibition of adenylyl cyclase
b.Caused by decreased receptors
c. Cross tolerance with alcohol
d.Cross tolerance with opioids
Which of the following is not a hazard of marijuana
use?
a. Development of schizophrenia
b.Development of squamous cell hyperplasia
c. Low birth weight and head circumference in
offspring
d.Development of insomnia
For which of the following is medical marijuana
approved?
a. Multiple sclerosis
b.Tourette’s syndrome
c. AIDS wasting syndrome
d.L-dopa-induced dyskinesias
Which of the following would be a use for CB1
selective antagonists?
a. Immune suppression
b.Neuroinflammation
c. Chronic pain
d.Obesity
Which of the following inhalants are used primarily as
sexual enhancers?
a. Volatile solvents
b.Nitrites
c. Gases
d.Aerosols
Which of the following results from heavy use of
inhalants?
a. Euphoria
b.Dizziness
c. Drowsiness
d.Delusions
Which of the following is not an effect of inhalant use
on the brain?
a. Demyelination
b.Slowed conduction
c. Spasticity
d.Increased sensory input
Which of the following is the typical cause of death
from inhalants?
a. Liver failure
b.Kidney failure
c. Cardiac arrhythmia
d.Stroke
Which of the following categories of drugs has a
stimulatory effect on the brain and may be used in
those with mental disorders to encourage
introspection?
a. Inhalants
b.Hallucinogens
c. Cannabinoids
d.Opioids
What is the mechanism of action for LSD?
a. Partial 5-HT2 receptor agonist
b.Full 5-HT2 receptor agonist
c. Partial dopamine receptor agonist
d.Full dopamine receptor agonist
Which of the following can be used to treat acute
adverse effects from LSD?
a. Benzodiazapines
b.Tricyclic antidepressants
c. Opiates
d.Antipsychotics
Which of the following interacts with a receptor that
usually causes dysphoria?
a. Psilocybin
b.Mescaline
c. Salvia divinorum
d.Phencyclidine
Which of the following is a dopamine and
norepinephrine reuptake inhibitor and also
antagonizes the NMDA receptor?
a. Psilocybin
b.Mescaline
c. Salvia divinorum
d.Phencyclidine
Which of the following hallucinogens can be
overdosed?
a. Psilocybin
b.Mescaline
c. Salvia divinorum
d.Phencyclidine
Which of the following is an action for MDMA?
a. Increased neurotransmitter release
b.NMDA receptor antagonism
c. Serotonin receptor agonist
d.Opioid receptor agonist
Which of the following is an action for LSD?
a. Increased neurotransmitter release
b.NMDA receptor antagonism
c. Serotonin receptor agonist
d.Opioid receptor agonist
Which of the following is an action for mescaline?
a. Increased neurotransmitter release
b.NMDA receptor antagonism
c. Serotonin receptor agonist
d.Opioid receptor agonist
Which of the following is an action for PCP?
a. Increased neurotransmitter release
b.NMDA receptor antagonism
c. Serotonin receptor agonist
d.Opioid receptor agonist
Which of the following is an action for salvia
divinorum?
a. Increased neurotransmitter release
b.NMDA receptor antagonism
c. Serotonin receptor agonist
d.Opioid receptor agonist
Which of the following describes the studied effect of
MDMA on serotonin in the brain?
a. Increases the number of serotonin transporters
b.Decreases the number of serotonin transporters
c. Increases the number of serotonin receptors
d.Decreases the number of serotonin receptors
Which of the following is associated specifically with
the abuse of cough syrup in large doses?
a. Delirium
b.Dissociative anesthesia
c. Memory loss
d.Disorientation