Download Morphogenetic Model for Radial Streaking in the Fundus of the

From: Morphogenetic Model for Radial Streaking in the Fundus of the Carrier State of X-Linked Albinism
JAMA Ophthalmol. 2013;131(5):691-693. doi:10.1001/jamaophthalmol.2013.39
Figure Legend:
Figure 1. Fundus autofluorescence image of the posterior pole of the right eye of the X-linked ocular albinism obligate carrier,
demonstrating the typical mud-splattered appearance of the retinal pigment epithelium. Hypoautofluorescent areas correspond to
hyperpigmented areas of retinal pigment epithelium. Similarly, hyperautofluorescent areas correspond to hypopigmented areas on
the color fundus photograph.
Date of download: 5/6/2017
Copyright © 2013 American Medical
Association. All rights reserved.
From: Morphogenetic Model for Radial Streaking in the Fundus of the Carrier State of X-Linked Albinism
JAMA Ophthalmol. 2013;131(5):691-693. doi:10.1001/jamaophthalmol.2013.39
Figure Legend:
Figure 2. Color fundus photograph and late-phase fluorescein angiogram. A, Color fundus photograph on a wide-angle instrument of
the right eye of the X-linked ocular albinism obligate carrier, demonstrating the typical mud-splattered appearance of the posterior
pole and the characteristic alternating hyperpigmented and hypopigmented peripheral streaks at the level of the retinal pigment
epithelium. B, Late-phase fluorescein angiogram of the same eye showing normal retinal vasculature, blocking in hyperpigmented
areas, and window defects in hypopigmented areas.
Hypofluorescent
areas
correspond to hyperpigmented areas of retinal pigment
Copyright
© 2013 American
Medical
Date
of download:
5/6/2017
epithelium.
Similarly,
hyperfluorescent areas correspond
to
hypopigmented
areas
Association. All rights reserved. on the color fundus photograph.
From: Morphogenetic Model for Radial Streaking in the Fundus of the Carrier State of X-Linked Albinism
JAMA Ophthalmol. 2013;131(5):691-693. doi:10.1001/jamaophthalmol.2013.39
Figure Legend:
Figure 3. Schematic model of clonal populations of retinal pigment epithelial precursor cells proliferating and migrating in the
peripheral fundus to produce the typical pattern of alternating hyperpigmented and hypopigmented streaks at the level of the retinal
pigment epithelium. Artist: David Rini, MFA, Department of Art as Applied to Medicine, The Johns Hopkins University School of
Medicine, 2012.
Date of download: 5/6/2017
Copyright © 2013 American Medical
Association. All rights reserved.