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Transcript
Abstract
Introduction:
Apoptosis – programmed cell death significantly participates in
maintaining of tissue homeostasis. Its alteration is leading to cancer disease.
Inositolhexaphosphate (IP6) is naturally occurring substance that is
present in most legumes, cereals and seems. IP6 and its lower phosphorylated
forms are also found in most mammalian cells, where they assist in regulatory
a variety of important cellular function (including regulation of cell cycle).
Methods:
This work has been engaged in the study of influence IP6 on apoptosis in
cells isolated out of colorectal cancer by in vitro quantification enzymatic
activity of caspase 3 in cell extract.
Results:
It has proved by the Student´s t-test that IP6 statistically significant
influence apoptosis in cells isolated out of colorectal cancer.