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Apoptosis
Apoptosis
Programmed cell death
(apoptosis) is triggered by cell
death signals that activate
inactive forms of DNAase and
proteinases (caspases) that
destroy the cell.
Apoptosis
Cell death signals may originate
outwith the cell (for example
from lymphocytes) and bind to a
surface receptor protein to
activate a protein cascade that
produces active caspases.
Apoptosis
• Death signals may also
originate within the cell, for
example as a result of DNA
damage the presence of p53
protein can activate a caspase
cascade.