Download Basic Immunology Course Code: Credit Units: 3

FORMAT FOR COURSE CURRICULUM
Course Title: Basic Immunology
Credit Units: 3
L
T
P/S
SW/F
W
2
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2
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Course Code:
Course Objectives: To establish foundations of immunology by gaining thorough
understanding of basic concepts of Immunology
Pre-requisites: Basic knowledge of biological sciences
Student Learning Outcomes: At the end of this course, the students will be able to:
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•
•
•
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Define and remember the key features of immune response.
Gain knowledge on the methods used to determine antigen antibody
interactions.
Illustrate the structure of primary and secondary lymphoid organs.
Remember the contributions of well- known immunologists to biomedical
science.
Safely perform basic lab techniques.
Course Contents/Syllabus:
Weightage
(%)
Module I
Descriptors/Topics
History & basic theories of immunology
Historical perspective; Important milestones and contributions of
scientists in Immunology, Edward Jenner, Karl Landsteiner, Paul
Ehrlich, Elie Metchinkoff, Peter Medawar, M Burnet, Niels K Jerne,
Rodney Porter, Susumu Tonegawa, Zinkernagel etc. Nobel laureates
in Immunology and their contributions to biomedical science, Theories
in Immunology : Clonal selection theory, Antigen instruction theory
Module II
Descriptors/Topics
Components of the immune system
Organs and cells of immune system, haematopoeisis, Concept of
renewal, enrichment, Importance of haemopoeitic stem cells (HSCs)
Concept of histocompatibility
Lymphoid cells and organs: evolutionary comparisons
Module III
10
30
30
TOTAL
CREDIT
UNITS
3
Descriptors/Topics
Exploring Innate & Adaptive Immunity
Innate immune system; Complement system, Innate immune
receptors, Innate response to infection, NK cells
Adaptive immune system; Components of adaptive immune system,
Primary & Secondary response, Concept of memory
Module IV
Descriptors/Topics
Antigen (basic concepts of hapten, carrier and super antigen,
antigenicity, immunogenicity, tolerogens, allergens), Antibody
isotypes, idiotypes, allotypes, Epitopes Antibody diversity, Class
switching, Fc structure and function, Monoclonal antibodies, Antigenantibody interactions
30
Pedagogy for Course Delivery: interactive classroom teaching from text books,
published reviews and articles
Lab/ Practicals details, if applicable:
List of Experiments:
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
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Blood smear Preparation
Identification of different immune cells in the blood
Serum isolation
Agglutination – blood typing.
Immunodiffusion
Assessment/ Examination Scheme:
Theory L/T (%)
Lab/Practical/Studio (%)
Total
75
25
100
Theory Assessment (L&T):
Continuous Assessment/Internal Assessment
End Term
Examination
Components
(Drop down)
CT
Attendance
Assignmemnts/Projects/Seminar/Quiz
Weightage
(%)
15
5
10
70
Lab/ Practical/ Studio Assessment:
Components
Weightage (%)
Continuous Assessment/Internal
Assessment
Class Test
Practical
Viva
(Practical
records
based)
15
5
10
End Term Examination
Practical
performance
Practical
record
Viva
40
10
20
Text
 Immunology, J. Kuby, 7th Edition, Fence Creek Publishing (Blackwell) (2012)
References:
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Immunology, D Male, J. Brostoff, DB Roth, Ivan Roitt, 7th edition, Mosby-Elsevier. (2006)
Janeway's Immunobiology, K. Murphy, 8th edition, Garland Science. (2012)
Cellular and Molecular Immunology, AK Abbas, AH Lichtman, S. Pillai, 6th edition, Elsevier
(2012)