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p. 337 #1, 2, 3, 4, & 10 p. 339 #1 p. 363 # 1, 2, 3, 4, 5, 6, 8, & 10 p. 365 #1, 2, 3, 5, 6, & 7 p. 337 #11 & 12 p. 363 #11, 12,13, & 14 p. 364 #29 1. A cross between dissimilar individuals to bring together their best characteristics is called A.Genetic engineering B.Inbreeding C.Hybridization D.Sequencing Answer: C 2. Crossing individuals with similar characteristics so that those characteristics will appear in the offspring is called A. Inbreeding B. Electrophoresis C. Hybridization D. Genetic engineering Answer: A 3. Varieties of purebred dogs are maintained by A. Selective breeding B. Hybridization C. Inbreeding D. Genetic engineering Answer: C 4. Changing the DNA of an organism is called A.Genetic engineering B.Hybridization C.Selective breeding D.Inbreeding Answer: A 10.A member of a population of genetically identical cells produced from a single cell is a A. Clone B. Plasmid C. Mutant D. Sequence Answer: A 1. Which of the following can be used to produce organisms with desirable traits? I. Inbreeding II. Genetic engineering III. Inducing mutations A. I only B. II only C. I and III only D. II and III only E. I, II, and III Answer: E 1. A normal human diploid zygote contains a full set of A. 23 chromosomes B. 46 chromosomes C. 44 chromosomes D. XXY chromosomes Answer: B 2. A chart that traces the inheritance of a trait in a family is called a(n) A. Pedigree B. Karyotype C. Genome D. Autosome Answer: A 3. Traits that are caused by the interaction of many genes are said to be A. Polyploid B. Linked C. Polygenic D. Autosomal Answer: C 4. An example of a trait that is determined by multiple alleles is A. Huntington’s disease B. ABO blood groups C. Down syndrome D. Hemophilia Answer: B 5. Most sex-linked genes are found on the A. Y chromosome B. O chromosome C. YY chromosome D. X chromosome Answer: D 6. Hemophilia is a genetic disorder that is A. Sex-linked B. Sex-influenced C. Fairly common D. More common in women than men Answer: A 8. A common genetic disorder characterized by bent and twisted red blood cells is A. Cystic fibrosis B. Hemophilia C. Sickle cell disease D. Muscular dystrophy Answer: C 10.The process of attempting to cure genetic disorders by placing copies of healthy genes into cells that lack them is known as A. Gene therapy B. DNA fingerprinting C. Rapid sequencing D. The Human Genome Project Answer: A 1. Which of the following can be observed in a person’s karyotype? I. Colorblindness II. Trisomy 21 III. Turner’s syndrome A. I only B. III only C. I and II only D. II and III only E. I, II, and III Answer: D 2. Which of the following conditions is caused by a sex-linked gene? I. Klinefelter’s syndrome II. Down syndrome III. Muscular dystrophy A. I only B. III only C. I and II only D. II and III only E. I, II, and III Answer: B 3. A. B. C. D. E. A child has colorblindness. Which genotype-phenotype combination is NOT possible in the child’s parents? The father does not carry the allele and does not have colorblindness. The mother carries one allele but does not have colorblindness. The father carries one allele but does not have colorblindness. The father carries one allele but has colorblindness. The mother carries two alleles and has colorblindness. Answer: C 5. Which pattern(s) of inheritance are consistent with the pedigree? I. Sex-linked II. Complete dominance III. Codominance A. I only B. II only C. I and II only D. II and III only E. I, II, and III Answer: B 6. What are the probable genotypes of the student’s parents? A. Mother – Ww; Father – ww B. Mother – ww; Father – ww C. Mother – WW; Father – Ww D. Mother – WW; Father – WW E. Mother – Ww; Father - Ww Answer: E 7. The student does not have a widow’s peak hairline, but her sister does. What are the girls’ probable genotypes? A. Student – Ww; sister – ww B. Student – WW; sister – Ww C. Student – ww; sister – Ww D. Student – ww; sister – ww E. Student – Ww; sister - Ww Answer: C 11. Compare hybridization and inbreeding. Why are they considered forms of selective breeding? Answer: Hybridization- cross dissimilar organisms; inbreeding – cross similar organisms; both involve selecting to breed organisms with the desired characterisitcs. 12. How do breeders produce new genetic variations not found in nature? Answer: By including mutations with chemicals or radiation 11. Describe how a karyotype is prepared and analyzed. Answer: Photographing cells in mitosis, cut out the chromosomes from the photographs, and group them together in pairs. They then check whether any chromosomes are missing or if there are extra copies. 12. What is the difference between autosomes and sex chromosomes? Answer: sex chromosomes – X and Y determine an individual’s sex; the remaining chromosomes are autosomal. 13. How can a family pedigree be helpful in determining the probability of having a child with a genetic disorder? Answer: A pedigree shows how a genetic trait has been passed from 1 generation to the next. This information can be used to infer the genotypes of family members and predict the likelihood that a child will have the disorder. 14. In the pedigree below, the shaded symbols indicate people who have hemophilia. Which mothers certainly are carriers? Why did the sons of person 3 not inherit the trait? Answer: Mothers 1 & 6 are carriers. Person 3 can pass the affected X chromosome only to his daughters; his sons inherit his Y chromosome and an X chromosome from their mother. 29. Analyze the human karyotype below. Identify the chromosomal disorder it shows. Answer: Turner’s syndrome; only 1X chromosome is present and there is no Y chromosome. Extra Questions to help you for the test… When a person decides what traits they desire in the offspring….. Answer: selective breeding Crossing a horse and a donkey to produce a mule is known as Answer: hybridization Breeding to maintain the desired traits of an organism…. Answer: inbreeding Making many copies of a gene is done through Answer: polymerase chain reaction (PCR) – see page 325 in book What is genetic engineering and how is it done? Answer: Manipulating DNA; reading and editing a DNA sequence and then inserting it into another living organism. What is a clone? Answer: genetically identical organisms (identical twins, Dolly the sheep) What kind of cells were used to make Dolly? Answer: an egg cell and a body cell What is a karyotype? Answer: a photograph of all the chromosomes in an organism What is the probability that a human child will be male? Answer: 50% What is the probability that a human sperm cell will carry an X chromosome? Answer: 50% What is a pedigree and how is it used? Answer: A chart of inheritance (like a family tree); used to determine whether a trait is inherited and how that trait is passed from one generation to the next; it can also determine whether an allele is dominant or recessive. Is it possible for a human child to be born with: 3 X chromosomes? 1 X chromosome? 0 X chromosomes? Answer: Yes: XXX – female with extra X chromosome Yes: XY – a male OR X – female with a missing X chromosome No: X chromosome contains genes vital for normal development; baby would not survive If a Y chromosome is present in a human karyotype then the person in question is a Answer: male Test is Tomorrow It is VERY short – only about 20 questions (multiple choice - 4 points each short answers – varies between 4 & 8 points; multiple parts are graded separately)