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BYM 501E FUNDAMENTALS OF BIOMEDICAL ENGINEERING (14030)
Inci ÇiLESiZ
Final Examination  7 January 2014  12.00-14.00
1.
What instruments (signal generator, multimeter, oscilloscope, etc.) would you use and how would you
design measurements to measure dynamic properties of a biomedical measurement system? Which
properties would you measure? Why and how? (15 points)
2.
Compare and contrast (you may think of blood tests, biopsy results, and alike) (a) sensitivity vs. specificity
and (b) accuracy vs. precision (2x3 points)
3.
Define, compare and contrast (advantages vs. disadvantages, etc.) the following terms in terms of
biomedical measurements and instrumentation and provide examples (e.g., name instruments, devices,
methods) for each set of terms (a) direct / indirect; (b) invasive / non-invasive; and (c) intra-corporeal / extracorporeal. (3x3 points)
4.
Show mathematically, that by using the augmented leads, detected bioelectric signal amplitude is increased
50% as compared to unipolar frontal plane leads without effecting the direction of the lead vector? (10
points)
5.
Correlate heart sounds with electrical and mechanical events of the cardiac cycle on a diagram showing time
evolution of (a) aortic and (b) left ventricular blood pressures, (c) EKG signal and (d) the heart sounds (at
least the major two!). (12 points)
6.
Compare and contrast within 5 sentences maximum macroshock vs. microshock in terms of electrical
hazards in a clinical environment. (4 points)
7.
Explain within 5 sentences maximum the function of driven-right-leg circuit. (5 points)
8.
Assume you are a staff biomedical engineer in a fully equipped hospital. One day, a patient with minor
injuries and acute severe headache is brought into the emergency room. You are informed that the patient
had collapsed (fainted) on an escalator going upwards (he or she was standing on the escalator). There are
no doctors around and you are called to take charge of the situation. What would you monitor, what
action(s) would you take, how and why? (10 points)
9.
Why are most bio-electrical signals monitored best using an instrumentation amplifier? (5 points)
From your PROJECTS: (2 points each, 24 points total)
10.
How is skin conductance measured and evaluated?
11.
What are advantages of biomagnetic diagnostics compared to EKG or EEG?
12.
How does a rehabilitation robot function?
13.
Why is EOG useful in assessment of sleep quality?
14.
What is the most critical part of a wearable artificial kidney?
15.
What is the diagnostic value of fetal heart monitoring?
16.
When and why is a heart pacemaker implanted in a cardiac patient?
17.
What is the clinical value of pulse oximetry?
18.
When is deep brain stimulation used clinically and how?
19.
What are major challenges in brain computer interface applications?
20.
Name the major differences between a regular bed side monitor and a smart healthcare chair.
21.
How does a glucose sensor function?
100 points total - GOOD LUCK!