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Transcript
EMBO conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
Co-Sponsors
Organisers
Chair : Gisou van der Goot
(EPFL, Switzerland))
Vice-Chair : Ivan Dikic
(Goethe University School of Medicine)
Scientific Committee
Harald Stenmark
(Norwegian Radium Hospital)
Guy Cornelis
(Biozentrum, Basel, Switzerland)
Pascale Cossart
(Institut Pasteur, Paris, France)
Jean Gruenberg
(University of Geneva, Switzerland)
David Holden
(Imperial College, London, UK)
Philippe Sansonetti
(Institut Pasteur, Paris, France)
Michael Way
(Cancer Research UK, London, UK)
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
1
Programme
Programme Schedule
Saturday 20 September
17:00
Arrival and registration
19:30
Supper
21:00
Get-together-drinks
Sunday 21 September
Session 1: Temporal control of trafficking events
Morning
Chair : Harald Stenmark (Norwegian Radium Hospital, Oslo, Norway)
08:50
Opening remarks
09:00
Catherine Rabouille (University Medical Center Utrecht)
How integrins trigger their unconventional secretion during epithelium
remodeling in Drosophila
09:35
Simona Polo (Istituto FIRC di Oncologia Molecolare, Italy)
The role of endocytosis in organizing and complexifying intracellular
signalling
10:10
Coen Kuijl (The Netherlands Cancer Institute Tumor Biology, Amsterdam)
The molecular mechanism of cholesterol control of late endosomal
transport by dynein motors
10:35-11:05
Coffee break
11:05-11:40
Jaime Mota (Imperial College London)
Interaction between intracellular Salmonella and post-Golgi trafficking
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
2
11:40-12:15
Jean Pieters (Biozentrum, Univ. Basel)
'Preventing lysosomal trafficking of pathogenic mycobacteria through
modulation of host signal transduction'
12:30
Lunch
(speakers available to sit with young investigators)
Session 2: Systems biology of cell biology and host-pathogen interactions
Afternoon
Chair : Jean Gruenberg (University of Geneva)
16:00
Lucas Pelkmans (ETHZ, Switzerland)
Towards systems analysis of endocytosis and virus entry in mammalian
cells
16:35
Linda Stuart (Harvard, Boston)
Systems approaches to phagocytosis
17:10
Barbara Burleigh (Harvard School of Public Health)
Global approaches to studying cellular invasion by Trypanosoma cruzi
17:45-18:15
Coffee break
18:15
Keynote lecture : Sponsored by the Journal of Cell Science
Pascale Cossart (Institut Pasteur, Paris)
Listeria monocytogenesis, a paradigm to study host-pathogen interaction
of an intracytoplasmic bacterium
19:30
Dinner (speakers available to sit with young investigators)
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
3
20:45
Poster session 1
Sponsored by :
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
4
Monday 22 September
Session 3: Unconventional membrane mediated processes
Morning
Chair : David Holden (Imperial College, London, UK)
09.00
Ludger Johannes (Curie Institute, Paris)
Mechanisms of membrane invagination and scission in clathrinindependent endocytosis
09:35
Jean Celli (Rock Mountain Laboratories, NIH, Montana)
Intracellular trafficking of Brucella determines temporal expression of
virulence genes
10.10
Marc Fivaz (University of Singapore)
A model for neuronal polarization based on local positive feedback and
membrane transport
10:35-11:05
Coffee break
11:05
Anne Ridley (King’s College London)
How cells move through other cells
11:40
Emmanuel Lemichez (University of Nice)
Bacterial induced transient macroapertures in endothelial cells
12:30
Lunch
(speakers available to sit with young investigators)
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
5
Session 4: . Pathogens: the ultimate cell biologists
Afternoon
Chair : Anne Ridley (University College London)
16.00
Vojo Deretic (University of New Mexico School of Medicine, USA)
The role of autohagy in mycobacterial infection
16:35
Raffi Aroian (UCSD)
Pore worms-- uncovering intrinsic cellular defenses against pore-forming
toxins using C. elegans
17:10
Bernd Helms (Dept. Biochem. & Cell Biology, Utrecht University)
Lipidome analysis of latex bead phagosome maturation
17:35-18:05
Coffee break
18:05
Volker Heussler (Bernhard Nocht Inst. Tropical Medicine, Hamburg)
Manipulation of host hepatocytes by the malaria parasite
18:40
Janet Deane (Sir William Dunn School of Pathology, University of Oxford)
Regulating type III secretion: components and complexes
19:30
Dinner (speakers available to sit with young investigators)
20:30
Poster session 2, sponsored by:
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
6
Tuesday 23 September
Session 5: Signalling and anti-signalling
Morning
Chair: Antonella de Matteis (Consorzio Mario Negri, Italy)
09:00
Kim Orth (University of Texas Southwestern Medical Center, Dallas)
Interference with cellular signalling cascades by YOP proteins
09:35
Ivan Dikic (Goethe University School of Medicine, Frankfurt, Germany)
Targeting ubiquitin networks
10:10
Lucile Espert (University of Montpellier, France)
Cell-to-cell membrane fusion induced by HIV-1 envelope glycoproteins
triggers autophagy and cell death in the uninfected CD4 T cells
10:35-11:05
Coffee break
11:05
Valeria Cavalli (Washington University, Saint Louis)
The role of axonal transport in mediating long-range biochemical signals
11:40-12:15
Marta Miaczynska (Int. Instit. Mol. and Cell Biology, Warsaw, Poland)
Signalling complexes on endosomes
12:30
Lunch (speakers available to sit with young investigators)
14:00
Excursion
19:30
Dinner
20:45
Poster session 3, sponsored by:
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
7
Wednesday 24 September
Session 6: Immune cells and their interaction with pathogens
Morning
Chair: Pascale Cossart (Pasteur Institute, Paris, France)
9:00
Frances Brodsky (Hooper Foundation, San Franscisco)
Endocytosis in the natural killer cell
9:35
Paul Lehner (University of Cambridge, UK)
Ubiquitination mediated down regulation of the immune response during
viral infection
10:10
Emily Eden (UCL Inst. Ophthalmology Cell Biology)
The role of PTP1B-mediated dephosphorylation in regulating EGFR
trafficking.
10:45-11:15
Coffee break
11:15
Natalie Strynadka (University of British Columbia, Vancouver)
Structural characterization of bacterial type III secretion apparatuses
11:50-12:25
Vincent Piguet (University of Geneva)
How HIV hides in dendritic cells
12:30
Lunch (speakers available to sit with young investigators)
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
8
Session 7: On the generation of tubules and vesicles
Afternoon
Chair: David Holden (Imperial College London)
16:00
Patricia Bassereau (Institut Curie, Paris)
Dynamics and thermodynamics of membrane deformation
16:35
Jean Gruenberg (University of Geneva)
Biogenesis and dynamics on intraluminal endosomal membranes
17:10
Guillaume Dumenil (Faculte de medecine Rene Descartes, Paris)
Neisseria meningitidis-induced host cell surface reorganization confers
mechanical resistance to bacterial microcolonies in the bloodstream
17:35-18:05
Coffee Break
18:05
Harald Stenmark (Norwegian Radium Hospital, Oslo)
sorting into multivesicular endosomes
18.40-19:15
Antonella de Matteis (Consorzio Mario Negri, Italy)
Role of phosphoinositides in the secretory pathway
19:30
Congress Dinner and Farewell party
Poster award ceremony
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
9
Thursday 25 September
Breakfast and Departure
Embo conference series:
At the joint edge of cellular microbiology & cell biology
Villars-sur-Ollon, Switzerland 20 – 25 September 2008
10