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*The answers to the questions in this powerpoint should be in your notes. Think back to the PET scans viewed in activity 2 of lesson 1. Different areas showed up as red or yellow in response to a stimulus. What composes those regions of the brain? (Why did those areas show up as red or yellow?) Answer on the next page. The basic functional unit of the brain and the nervous system is the NEURON. Write down the different parts of the neuron and and their functions. The answer SHOULD be in your notes. Look at the top part of the handout. See that the axon terminals (the end points of the axon) end near the dendrites of another neuron. The connection between the two neurons is called the synapse. The space itself is called the synaptic space/cleft. Presynaptic- neuron whose axon forms a synapse with another neuron, sends out information Postsynaptic- neuron whose dendrites forms a synapse with the axon of the presynaptic neuron, receives information There is no physical structure connecting the two neurons. Look at the parts of the brain’s reward system. The neurons affected by drugs introduced to the body are in the ventral tegmental area (VTA). Those cells extend their axons to nerve cells in an area of the brain called the nucleus accumbens. Some nerve fibers extend to part of the frontal region of the cerebral cortex. How Do Neurons Communicate? Axon- large part of the neuron, and sends information through the axon terminals to the synapse This is where the presynapse is found. Dendrite- branches from the cell body, receives information from the synapse This is where the postsynapse is found. 1. 2. 3. What purpose do synapses serve? The brain regulates body functions, behaviors, and emotions. Neurons are the cells that fulfill these functions. How do neurons do this? Refer to handout, Master 2.3 How Do Neurons Communicate? Discuss with a partner about the diagrams, and then write a summary of how you think the neurons are interacting at each step. a. You may not know all of the terms that might be needed for the summary, but you can use any terms you think would work. 1. 2. 3. Synapses serve to connect neurons, enabling neurons to communicate by passing signals between them. Neurons control these functions by passing signals across the synapse from one neuron to the next. These signals dictate whether the receiving neuron is activated. The summaries of the diagrams should be descriptive of the images. https://science.education.nih.gov/supplements/nih2/Addiction/activities/lesson2_n eurotransmission.html Click on the youtube link. Neurotransmission At this point, please go back to your diagram summaries and revise them. You should be able to use correct terminology and have a better understanding of what is going on. 1. This diagram shows the component parts of the neurotransmission process between electrical impulses. 4. The neurotransmitter is in the synaptic cleft and binds to the receptor on the postsynaptic neuron’s membrane. 2. An electrical impulse travels down the axon toward the presynaptic nerve terminals. 5. Neurotransmitter molecules are still bound to the receptors, and an electrical signal passes along the postsynaptic neuron away from the synapse. 3. The vesicles containing neurotransmitter move toward the neuron cell membrane at the end of the axon. The vesicles fuse to the membrane and then release their contents (neurotransmitter molecules) into the synaptic cleft. 6. Neurotransmitter molecules are released from the receptors. Neurotransmitter molecules are taken back up into the presynaptic neuron through the transporter. Once inside the presynaptic terminal, the neurotransmitter molecules are repackaged into vesicles. Unit IV, Lesson II, Activities I and II End