* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Genetics Unit Study Guide – Teacher Version
No-SCAR (Scarless Cas9 Assisted Recombineering) Genome Editing wikipedia , lookup
Cancer epigenetics wikipedia , lookup
Mitochondrial DNA wikipedia , lookup
Nucleic acid analogue wikipedia , lookup
Genomic library wikipedia , lookup
Public health genomics wikipedia , lookup
SNP genotyping wikipedia , lookup
Heritability of IQ wikipedia , lookup
United Kingdom National DNA Database wikipedia , lookup
Neuronal ceroid lipofuscinosis wikipedia , lookup
Nucleic acid double helix wikipedia , lookup
Genealogical DNA test wikipedia , lookup
DNA paternity testing wikipedia , lookup
Transgenerational epigenetic inheritance wikipedia , lookup
Epigenomics wikipedia , lookup
DNA vaccination wikipedia , lookup
Genome (book) wikipedia , lookup
Cre-Lox recombination wikipedia , lookup
DNA supercoil wikipedia , lookup
Site-specific recombinase technology wikipedia , lookup
Deoxyribozyme wikipedia , lookup
Point mutation wikipedia , lookup
Extrachromosomal DNA wikipedia , lookup
Non-coding DNA wikipedia , lookup
Epigenetics of diabetes Type 2 wikipedia , lookup
Molecular cloning wikipedia , lookup
Vectors in gene therapy wikipedia , lookup
Genome editing wikipedia , lookup
Therapeutic gene modulation wikipedia , lookup
Cell-free fetal DNA wikipedia , lookup
Nutriepigenomics wikipedia , lookup
Helitron (biology) wikipedia , lookup
Hardy–Weinberg principle wikipedia , lookup
Artificial gene synthesis wikipedia , lookup
Genetic engineering wikipedia , lookup
Quantitative trait locus wikipedia , lookup
Designer baby wikipedia , lookup
Dominance (genetics) wikipedia , lookup
Genetics Unit Study Guide Vocabulary: 1. The principle that describes that genes segregate without influence on each others inheritance: Law of Independent Assortment 2. During the formation of gametes, independent assortment occurs during Meiosis 3. Mendel’s hypothesis that two factors for each trait are segregated during the formation of gametes is explained by the law of 4. Segregation If a corn plant has a genotype of Ttyy, what are the possible genetic combinations that could be present in a gamete (single grain of pollen) from this plant? Ty and ty 5. The law of independent assortment states that the two alleles for each trait will separate during meiosis 6. The law of segregation states that genes will separate during meiosis 7. BR Br bR Br BR BBRR BBRr BbRR BbRr Br BBRr BBrr BbRr Y bR BbRR BbRr X Br BbRr Bbrr A male guinea pig with black, rough hair (BbRr) was crossed with a female guinea pig with black, rough hair (BbRr). The Punnett square contains the partial results from this mating. (B=black, b=white, R=rough, r=smooth) According to the figure above, what is the genotype for X? bbRR 8. Using the diagram above, explain the pattern of inheritance for hemophilia (a blood disease) trait. 9. Sex-linked inheritance Above is a pedigree for the recessive trait, attached ears (aa). The dominant trait is unattached ears (A). the black circles indicate people who have the recessive trait. Using the chart, what would be the genotype of person I,2? XH Xh Xh X HX h XhXh Y X HY 4 Aa h = hemophiliac H = normal 10. Using the chart above, how many offspring will be hemophiliacs? 2 11. The phenotype of box 4 is 12. In fruit flies, the gene for red eyes (R) is dominant and the gene for sepia eyes (r) is male hemophiliac recessive. What are the possible combinations of genes in the offspring of two red-eyed heterozygous flies (Rr)? RR, Rr, rr 13. The appearance of an organism is its phenotype 14. In a two-factor cross between an individual with the genotype RRYY and an individual with the genotype rryy, all of the offspring will have the genotype RrYy 15. A segment of DNA that controls a particular hereditary trait is called a gene 16. The genetic makeup of an organism is called its genotype 17. Having two similar alleles for a trait is called homozygous 18. A cross between two plants that have pink flowers produced plants that have red, pink, or white flowers. What is the most likely explanation for these results? Incomplete dominance 19. An organism in which two alleles for a trait are different is 20. Tallness (T) is dominant to shortness (t) in pea plants. What is the genotype of a pea plant that is heterozygous for tallness? 21. heterozygous Tt An individual heterozygous for a trait and an individual homozygous recessive for the trait are crossed and produce offspring that are of how many different phenotypes? _2_ 22. A family has eight children. Six children have second toes that are longer than the big toe. Two children have second toes that are shorter than the big toe. What are the most likely genotypes of the parents? Heterozygous 23. A homozygous individual would have what possible genotype? 24. If two parents with dominant phenotypes produce an offspring with a recessive phenotype, what can you say about the parents? 25. Homozygous dominant, homozygous recessive, or heterozygous Which diagram above correctly illustrates the fusion of normal gametes that will most likely produce a human male? 27. They are heterozygous In a monohybrid cross between two heterozygous parents, one would expect the offspring to be 26. Two dominant or two recessive 3 or 4 What is genetic engineering? _____manipulating dna using technology_______ 28. List the steps to genetically modify an organism (to make recombinant DNA). A gene is cut from one organism’s DNA. Then, the second organism’s DNA is cut open so the gene can be spliced into the DNA. Once the gene is in place, the DNA can be spliced back together. 29. What is a clone? ____An identical copy with the exact DNA________ 30. What is recombinant DNA? _____artificially modified DNA___ 31. What is the ethical issue with genetically modifying organisms?_______People are against the idea of humans “playing God” by manipulating natural DNA______ Problems: Show all your work on a separate sheet of paper. 32. Crosses between red and white shorthorn cattle result in roan offspring and is a result of incomplete dominance. Is it possible to produce a true breed in strain of roan cattle? Why or why not? No. Roan is a heterozygous condition, so it is not possible to be “purebred” or a “true breed”. 33. Polydactyly (presence of an extra finger) is due to a dominant factor. When one parent is polydactylous, but heterozygous, and the other parent is normal, what would be the probability of their having a child without polydactylous? 50% or 2:2 Pp pp Pp pp 34. Short hair is dominant over long hair in guinea pigs. A short-haired guinea pig, one of whose parents was long-haired, was mated with a long-haired animal. What types of offspring could be produced? In what ratio? It would not be possible to have two long-haired parents (hh) to have a short-haired offspring. 35. Diabetes is thought to be inherited as a recessive (d) trait. Two people without diabetes have a diabetic child. What are the genotypes of the parents and of the offspring? Dd and Dd 36. Albinism occurs commonly in animals, and it is always recessive to the normal. Six brown and five albino mice were born to parents who were likewise brown and albino. What is the genotype of the brown parent? Heterozygous (Bb) Aa aa Aa aa 37. Supposing brown eyes in people (B) is dominant to blue (b), could a marriage between two blue-eyed people produce a brown-eyed child? No. (bb x bb) Could a marriage between a homozygous brown-eyed person and a blue-eyed person result in blue-eyed children? No. (BB x bb) Could two brown-eyed people have a blue-eyed child? Yes. (Bb x Bb) Explain all of your answers by supplying the proper genotype. 38. A woman with heterozygous type A blood and a man with type O blood want to know the probability of having a child with type O blood. 50% Ao oo Ao oo 39. A man really wants to have a baby with type AB blood so he can brag to his friends that his kid is rare. Is it possible for a baby to get type AB blood if the mom has type O blood? Prove your answer showing all work. No. Ao Bo Ao Bo 40. Tay-Sachs disease is a fatal genetic disorder caused by a recessive allele. The pedigree chart below shows the appearance of the disease in three generations of a family. Tell the genotype or possible genotypes of each member of the family. Be sure to define your variables. Tt Tt Key: TT or Tt = Normal male Tt Tt = Tay-Sachs male tt = Normal female 6 tt = Tay-Sachs female 41. On a certain day in a local hospital, two male babies were born. Shortly after the mothers returned home with their infants, Mrs. Robinson discovered a tag marked “K” on her baby. The other mother, Mrs. Koffer, insisted she had her own baby and refused to exchange. The matter came to court where all concerned agreed to submit to blood test. Here are the results: Mrs. Robinson – Type O Mrs. Koffer – Type O Mr. Robinson – Type O Mr. Koffer – Type AB Baby taken home by the Robinsons – Type A Baby taken home by the Koffers – Type O Did a switch occur? Explain using Punnett Squares to support your answer. Yes. oo oo Ao Bo oo oo Ao Bo