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Transcript
Clp proteins in photosynthetic organisms: An essential family of molecular chaperones and proteases Handledare: Adrian Clarke Molecular chaperones and proteases are vital for regulating the function and structure of most proteins within a cell. They are found in all organisms and are separated into many different families. One such family is Clp, which in photosynthetic organisms plays an essential role for cell function and overall survival. My group has been studying the Clp family of molecular chaperones and proteases for many years in several different model photosynthetic organisms, ranging from the unicellular cyanobacterium Synechococcus to the higher plant Arabidopsis thaliana. Work has also begun on Clp proteins that reside in the unique plastid of the parasite Plasmodium falciparum, the causal agent of human malaria. Exam projects include a wide range of techniques, including PCR-based gene cloning, DNA sequencing, protein expression, protein purification, and biochemical determinations of protein structure and function. Many projects are available and can be tailored to the student's particular interests. Interested students should contact me by email at [email protected]