Download Clp proteins in photosynthetic organisms: An essential family of

Clp proteins in photosynthetic organisms: An essential
family of molecular chaperones and proteases
Handledare: Adrian Clarke
Molecular chaperones and proteases are vital for regulating the function and
structure of most proteins within a cell. They are found in all organisms and
are separated into many different families. One such family is Clp, which in
photosynthetic organisms plays an essential role for cell function and overall
survival. My group has been studying the Clp family of molecular chaperones
and proteases for many years in several different model photosynthetic
organisms, ranging from the unicellular cyanobacterium Synechococcus to the
higher plant Arabidopsis thaliana. Work has also begun on Clp proteins that
reside in the unique plastid of the parasite Plasmodium falciparum, the causal
agent of human malaria. Exam projects include a wide range of techniques,
including PCR-based gene cloning, DNA sequencing, protein expression,
protein purification, and biochemical determinations of protein structure and
function. Many projects are available and can be tailored to the student's
particular interests. Interested students should contact me by email at
[email protected]