Download CHAPTER 3-Protein-In Class Activity

CHAPTER 3- MACROMOLECULES-Protein
Name the four important Macromolecules group.
Which ones polymer structure is different from the other three group?
Define Macromolecule/Polymer
A dehydration reaction occurs when two monomers bond together through the
loss of a water molecule
Draw and explain what is a dehydration reaction.
Polymers are disassembled to monomers by hydrolysis reaction, a reaction that is
essentially the reverse of the dehydration reaction
Polymer’s name= Protein (Polypeptide)………….Monomer’s name=??????
Polymer’s name= Nucleic Acid (Polynucleotide)…………….Monomer’s name=?????
Polymer’s name=Polysacharide………………………Monomer’s name=?????
PROTEIN:
Draw the structure of amino acid (aa) and label each part’s name.
Draw and show how two aa bind together and go through dehydration reaction.
Condensation reactions bond the carboxyl group of one amino acid to the amino
group of another to form a peptide bond
There are _______different amino acids exist that they are different in their
_________from each other.
How functional group (R-group) affects reactivity?
Define the N-terminus and C-terminus of a polypeptide. Draw a schematic
polypeptide showing the C and N terminals.
Name some of the protein functions in the body with their examples.
Define Primary structure of a protein with example
Define Secondary structure of a protein with example
Define Tertiary structure of a protein with example
Define Quaternary structure of a protein with example
Secondary structure, found in most proteins, consists of coils and folds in the
polypeptide chain (back bone)
Tertiary structure is determined by interactions among various side chains (R
groups)
Typical secondary structures are: ________________ and ___________________.
We only see Hydrogen bonds in the _______________level of organization
The interactions between the R-groups at the tertiary level of organization could be
any of: hydrogen bonds, ionic bonds, hydrophobic interactions, and van der Waals
interactions, disulfide bridges.
Define what this sentence means: “Note that protein structure is hierarchical”.
Please explain by giving example
The sickle cell hemoglobin disease is being initiated by the disorder in __________level
of organization. However this mutation eventually alters __________________ level of
organization.
The STRUCTURE and FUNCTION of a protein is tightly related therefore a
denatured protein is biologically inactive
What is the mechanism of protein Folding in the cell? Please name the involved
molecule.
X-Ray Crystallography is a method to determine___________________.
Based on Miller’s experiment what was the first living entity on earth?
Explain Miller’s Experiment.
Here is how you show the structure of ONE Aminoacid:
Here is how you show THREE Aminoacids bind together through covalent bonds
(peptide bonds):