Download Abbreviation Protein Name Function AKT3 AKT serine/threonine

Abbreviation
Protein Name
Function
AKT3
AKT serine/threonine protein
cell signaling in response to insulin and growth factors, involved in cell
kinase family
proliferation, differentiation, apoptosis, tumorigenesis, as well as
glycogen synthesis and glucose uptake.
ARFIP2
BRSK2
ADP-ribosylation factor
GTP binding protein of Ras superfamily involved in vesicular
interacting protein 2
intracellular traffic
BR serine/threonine kinase 2
related to AMP activated protein kinase involved in energy
homeostasis
BTG1
B-cell translocation gene 1,
Immediate early gene, interacts with general transcription complex,
anti-proliferative gene
transcription factors and modulates intracellular signal transduction
cascades
CHD9
COPS7B
Chromodomain-helicase-DNA-
ATP dependent chromatin remodeling, interacting partner determines
binding protein 9
whether repressor/activator
COP9 signalosome complex
related to 26S ribosome regulatory complex
subunit 7b,
EPC1
Enhancer of polycomb
transcriptional repressor
homolog 1
ERBB3
FBXW7
Receptor tyrosine-protein
member of the epidermal growth factor receptor (EGFR) family of
kinase erbB-3
receptor tyrosine kinases, heterodimerization leads to cell proliferation
F-box/WD repeat-containing
F-box proteins constitute one of the four subunits of ubiquitin protein
protein 7
ligase complex called SCFs (SKP1-cullin-F-box), which function in
phosphorylation-dependent ubiquitination
IPO7
Importin-7
prevents the activation of Ran's GTPase by RanGAP1 and inhibits
nucleotide exchange on RanGTP, and also binds directly to nuclear pore
complexes
JARID2
Jumonji, AT rich interactive
regulator of cell proliferation
domain 2
MECP2
Methyl CpG binding protein 2
repressing/silencing other genes
NDEL1
Nuclear distribution protein
binds strongly to centrosomes in interphase and localized to mitotic
nudE-like 1
spindles in early M phase.
Decaprenyl-diphosphate
an enzyme that elongates the prenyl side-chain of coenzyme Q, or
synthase subunit 1
ubiquinone, one of the key elements in the respiratory chain
Tyrosine-protein phosphatase
signaling molecule involved in cell growth, differentiation, mitotic cycle
PDSS1
PTPN9
non-receptor type 9
RBM15
Putative RNA-binding protein
suppressor function
15
RGS2
Regulator of G-protein
family member of G protein coupled receptor
signaling 2
SIRT1
sirtuin (silent mating type
deacetylates proteins that contribute to cellular regulation (reaction to
information regulation 2
stressors, longevity)
homolog) 1
SLC2A1
Solute carrier family 2
facilitated glucose transporter, member 1 or GLUT1
STK39
STE20/SPS1-related proline-
function in the cellular stress response pathway
alanine-rich protein kinase
Serine/threonine-protein
nuclear serine/threonine kinases involved in the regulation of
kinase tousled-like 2
chromatin assembly
TRIB2
Tribbles homolog 2
regulates MAPK (mitogen activated protein kinases) signaling pathways
TYRO3
Tyrosine-protein kinase
interacts with the PI3 kinases (phosphatidylinositide-3-kinase) signaling
receptor
pathway and GAS6 (growth arrest specific 6) involved in cell
TLK2
proliferation
WDTC1
WD and tetratricopeptide
highly conserved, regulate cellular functions, such as cell division, cell
ZFYVE9
repeats 1
fate, transcription, transmembrane signalling
Zinc finger FYVE domain-
anchoring protein involved in TGF beta signaling, phosphorylating
containing protein 9
transcription factors