Download Spring 2015-Chapter 6

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Obligate aerobes and
facultative organisms have
both catalase and SOD; some
facultative have SOD but lack
catalase. Most obligate
anaerobes lack both enzymes
Superoxide is a
highly toxic
product- as is
peroxideHence, if they
are not
removed the
cell dies.
Obligate anaerobes are killed by a toxic form of oxygen termed superoxide (O22--). Superoxide is
converted to O2 and toxic hydrogen peroxide (H2O2) by an enzyme called superoxide dismutase.
H202 is converted to water and molecular oxygen by an enzyme termed catalase.
Role of catalase, peroxidase and superoxide dismutase in anaerobiosis