Download RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR I

GenWay Biotech, Inc.
6777 Nancy Ridge Drive
San Diego, CA 92121
Tel: (858)458-0866
Fax: (858)458-0833
[email protected]
RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR I recombinant
protein
Catalog Number: 10-783-79727
Related Product Names:
- IGF1 protein; IGF1; IBP1; RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR I
- IGF-IA; Somatomedin-C; Mechano growth factor; MGF; Insulin-like growth factor IA
- Gene Information Information in yellow represents specific gene information and does not necessarily represent specific product
details. For more information please contact [email protected].
Gene Name: IGF1
Gene Name Synonym: IBP1
Gi #: N/A
NCBI Acc #: NP_000609.1
Swiss Prot Acc #: P01343
Length (aa): N/A
Mol. Weight (Da): 17026
Chrom Location: N/A
Specificity: IGF-I
Activity: =>1x10(e)6 U/mg
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is <= 1.0
ng/ml.
Concentration: 1mg/ml
Peptide Sequence: The sequence of the first 5 N-terminal amino acids was found to be GPETL. N-terminal
methionine has been completely removed enzymatically.
Endotoxin Level:
Preparation: Purified recombinant human IGF-1 produced by E.coli.
Purity/Purification: SDS PAGE: >98%
Crossreactivity: Human
Format: Purified recombinant protein - liquid
Storage: Store at -70C. For long term storage. the addition of a carrier protein is recommended.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Stability: 18 months from date of despatch.
Shipping: Products may be shipped on ice pack or dry ice.
APPLICATIONS for IGF1 PROTEIN:
FuncS: Tested
TESTING: (secondary reagents and protocols)
Not Available
IGF1 PROTEIN TARGET DESCRIPTION:
Synonym Names for IGF1 protein: IGF1; IBP1; IGF-IA; Somatomedin-C; Mechano growth factor; MGF;
Insulin-like growth factor IA
Function: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin
but have a much higher growth-promoting activity.
Subcellular Location: Secreted.
Disease: Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747].
IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness
and mental retardation.
Similarity: Belongs to the insulin family.
RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR I reacts with human.
OMIM: 147440; gene. [NCBI / EBI]
608747; phenotype. [NCBI / EBI]
Pathways:
KEGG pathway: Focal adhesion 04510
KEGG pathway: Glioma 05214
KEGG pathway: Long-term depression 04730
KEGG pathway: Melanoma 05218
KEGG pathway: Prostate cancer 05215
KEGG pathway: mTOR signaling pathway 04150
Reactome Event:Hemostasis 109582
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact
GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: IGF1 protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of IGF1 protein vial. For products with volumes of 200 µL or
less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop
centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed
on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from SwissProt/TrEMBL and NCBI. To better serve our clients with everything we know about IGF1 protein, all related
information, articles, resources about IGF1 protein are being stored on our online database. Let us know if you
have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any
legal liability or responsibility for the accuracy, completeness or utility of any information, product or process
disclosed.
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Tel: (858)458-0866 Fax: (858)458-0833 Email: [email protected]
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