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Honors Bio: Nucleic Acids and Protein Synthesis Study Guide Stuff to Know: o Who discovered the structure of DNA? __________________________________________ o DNA is made of two nucleotide chains, containing: ___________________________________ ____________________________________________________________________ o Be able to label a nucleotide!! o In DNA, the 4 nitrogenous bases are? __________________________________________ o In DNA, the sugar is called: ______________________________ It is a pentose sugar, meaning the molecular formula is: __________________________________ o Purines have a ________________________-ring structure and include the bases ________________________ and _________________________. o Pyrimidines have a ________________________-ring structure and include the bases ________________________ and _________________________. o DNA takes on the shape of a __________________________________ (looks like a twisted ladder”, where the rungs are the ___________________________ and the poles are the ____________________________________________________________________ o The process of copying DNA? ___________________________________________ o When does this copying take place? _______________________________________ o Any change to DNA is called a(n)? _________________________________________ o Mutations can lead to what situations? __________________________________________ o RNA stands for _________________________________________________________ o Complimentary base pairing for RNA: A pairs with ________ and C pairs with _________ o The sugar in RNA? ____________________________________ o What do RNA and DNA have in common? ________________________________________ o What are the differences between RNA and DNA? __________________________________ ___________________________________________________________________ o 3 types of RNA: ______________________(mRNA), _________________ (tRNA) and ______________________ (rRNA). What is the purpose of each? o mRNA: _______________________________________________________________ o tRNA: _______________________________________________________________ o rRNA: _______________________________________________________________ o The “building blocks” of RNA and DNA? _____________________________________ o The “building blocks” of proteins? ______________________________________ o Codon = ___________________________________________ (each codon codes for an amino acid… example: AUG codes for __________________/methionine o Know how to use the codon wheel/chart!! Know the processes of: *Replication: original DNA strand to complimentary DNA strand Example: original DNA: AAA TTG CCG replicated DNA: TTT AAC GGC (write the replicated strand below): TAC TTA CCG TCA ATC ____________________________________________________ *Transcription: process of transcribing DNA to mRNA original DNA: AAA TTG CCG mRNA: UUU AAC GGC (phenylalanine asparganine glycine) Practice (transcribe this original DNA strand): TAC TTA CCG TCA ATC ____________________________________________________ Corresponding AA sequence? ____________ ____________ ____________ ____________ ____________ *Translation: mRNA translates a message to tRNA original DNA: AAA TTG CCG mRNA: UUU AAC GGC, tRNA: AAA UUG CCG Practice (translate this original DNA strand): TAC TTA CCG TCA ATC ____________________________________________________ o Be able to: o replicate, transcribe, look up A.A. sequence and translate from an original DNA strand!!! o label a nucleotide o answer critical thinking questions o describe the terminology/process/function of: o Replication: ____________________________________________________________ o Transcription: __________________________________________________________ o Translation: ____________________________________________________________ o Pentose sugar: __________________________________________________________ o Genetic code: ___________________________________________________________ o Mutation: _____________________________________________________________ o mRNA: _______________________________________________________________ o tRNA: _______________________________________________________________ o rRNA: _______________________________________________________________ o Human Genome: _________________________________________________________ STUDY!!! PRACTICE!! STUDY SOME MORE111