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Shier, Butler, and Lewis: Hole’s Human Anatomy and Physiology, 11th ed. Chapter 18: Nutrition and Metabolism Chapter 18: Nutrition and Metabolism I. Why We Eat A. Nutrients are __________________________________________________________ B. Macronutrients are______________________________________________________ C. Micronutrients are ______________________________________________________ D. Besides nutrients, the body also requires ____________________________________ E. Digestion breaks down __________________________________________________ F. Metabolism refers to ____________________________________________________ G. Anabolism is __________________________________________________________ H. Catabolism is __________________________________________________________ I. Essential nutrients are ____________________________________________________ J. Leptin regulates ________________________________________________________ K. Cholecystokinin signals _______________________________________ after eating while ___________________________________________________ stimulates appetite. II. Carbohydrates A. Introduction 1. Carbohydrates are ________________________________________________ 2. The body uses carbohydrates for _____________________________________ B. Carbohydrate Sources 1. Sources of polysaccharides are ______________________________________ 2. Sources of disaccharides are ________________________________________ 3. Sources of monosaccharides are _____________________________________ 4. Digestion breaks carbohydrates into __________________________________ 5. Cellulose provides ________________________________________________ 6. Other sources of fiber are ___________________________________________ C. Carbohydrate Utilization 1. Monosaccharides that are absorbed from the digestive tract include _________ __________________________________________________________________ 18-1 2. The liver enzymes ________________________________________________ that ______________________________________________________________ 3. Glycogenesis is _______________________________________________ and occurs in __________________________________________________________ 4. Glycogenolysis is ______________________________________________ and occurs in __________________________________________________________ 5. Excess glucose that cannot be stored as glycogen is converted to ___________ 6. Cells use some carbohydrates to produce ______________________________ 7. Gluconeogenesis is_____________________________________________ and occurs in __________________________________________________________ D. Carbohydrate Requirements 1. A recommended daily carbohydrate intake is ___________________________ 2. The average diet contains________________________ of carbohydrates daily. III. Lipids A. Introduction 1. Lipids are ____________________ that include _________________________ __________________________________________________________________ 2. The functions of lipids are __________________________________________ __________________________________________________________________ B. Lipid Sources 1. Triglycerides are found in __________________________________________ 2. Saturated fats are found in __________________________________________ 3. Unsaturated fats are found in ________________________________________ 4. Cholesterol is found in _____________________________________________ C. Lipid Utilization 1. Fats mainly supply ________________________________________________ 2. Gram for gram, fats contain _________________________________________ as carbohydrates or proteins. 3. Before a triglyceride molecule can release energy, it must undergo __________ __________________________________________________________________ 4. Digestion breaks triglycerides down into ______________________________ 18-2 5. Glycerol and fatty acids are transported in the ________________________ to the _______________________________________________________________ 6. Beta-oxidation is _________________________________________________ 7. Fatty acid oxidases function to ______________________________________ 8. Excess acetyl CoA is converted to ____________________________________ 9. Glycerol is used to ________________________________________________ 10. Glycerol and fatty acids can react together to form ___________________ and can be stored in _____________________________________________________ 11. The liver can convert fatty acids to __________________________________ 12. Essential fatty acids are ___________________________________________ 13. The liver uses free fatty acids to synthesize____________________________ __________________________________________________________________ 14. The liver regulates the amount of cholesterol in the body by ______________ __________________________________________________________________ 15. Cholesterol is not an energy source but it used to _______________________ __________________________________________________________________ D. Lipid Requirements 1. The American Heart Associate recommends that the diet not exceed_________ ___________________________________________________________from fat. 2. Dietary fats must supply the required amounts of ________________ vitamins. IV. Proteins A. Introduction 1. Proteins are polymers of ___________________________________________ 2. Functions of proteins are ___________________________________________ __________________________________________________________________ 3. Deamination is ________________________________________________ and occurs in the _______________________________________________________ 4. Urea is _________________________________________________________ 5. Using structural proteins to generate energy causes ______________________ __________________________________________________________________ B. Protein Sources 18-3 1. Foods rich in proteins are ___________________________________________ __________________________________________________________________ 2. Essential amino acids are ___________________________________________ 3. All twenty amino acids must be present in the body for ___________________ __________________________________________________________________ 4. Complete proteins contain __________________________________________ 5. Incomplete proteins has too little _____________________________________ __________________________________________________________________ 6. Sources of complete proteins are _____________________________________ 7. Sources of incomplete proteins are ___________________________________ C. Nitrogen Balance 1. Nitrogen balance is _______________________________________________ 2. A person who is starving has a negative nitrogen balance because ___________ __________________________________________________________________ 3. Examples of persons with positive nitrogen balances are` _________________ __________________________________________________________________ D. Protein Requirements 1. The amount of protein requires varies according to ______________________ __________________________________________________________________ 2. The recommended intake of protein per day is __________________________ __________________________________________________________________ 3. A pregnant woman requires _____________________ extra grams per day and a nursing mother requires ____________________________ extra grams per day. 4. Nutritional edema results from ______________________________________ __________________________________________________________________ V. Energy Expenditures A. Introduction 1. ___________________________________________________ supply energy. 2. If the diet is deficient of energy-supplying nutrients, _____________________ __________________________________________________________________ 3. Excess intake of energy supplying nutrients may lead to __________________ 18-4 B. Energy Values of Foods 1. The amount of potential energy a food contains can be expressed as _________ __________________________________________________________________ 2. A calorie is defined as _____________________________________________ 3. A large calorie is _________________________________________________ 4. A kilocalorie is ___________________________________________________ 5. A___________________________ is used to measure caloric contents of food. 6. Caloric values determined in a bomb calorimeter are somewhat higher than ___ ___________________________________________________________ because __________________________________________________________________ 7. Cellular oxidation yields on average about _____________________________ from 1 gram of carbohydrate, ___________________________ from one gram of protein, and ______________________________________ from one gram of fat. C. Energy Requirements 1. The factors that influence energy needs are _____________________________ __________________________________________________________________ 2. Basal metabolic rate is _____________________________________________ __________________________________________________________________ 3. ___________________________________________can be used to estimate a person’s BMR. 4. The BMR indicates _______________________________________________ __________________________________________________________________ 5. The BMR for an average adult indicates _______________________________ __________________________________________________________________ 6. BMR varies with _________________________________________________ __________________________________________________________________ 7. ________________________________________ requires the body’s greatest expenditure of energy. 8. Growing children and pregnant women require more calories because _______ __________________________________________________________________ 18-5 D. Energy Balance 1. A state of energy balance exists when _________________________________ __________________________________________________________________ 2. A positive energy balance is _____________________________________ and body weight ________________________________________________________ 3. A negative energy balance is _____________________________________ and body weight ________________________________________________________ E. Desirable Weight 1. The most common nutritional disorders reflect __________________________ 2. Overweight is defined as ___________________________________________ 3. Obesity is _______________________________________________________ 4. When a person needs to gain weight, diet can be altered to include __________ __________________________________________________________________ VII. Vitamins A. Introduction 1. Vitamins are _____________________________________________________ __________________________________________________________________ 2. Provitamins are __________________________________________________ 3. Vitamins can be classified based on __________________________________ 4. Fat-soluble vitamins are ____________________________________________ 5. Water-soluble vitamins are _________________________________________ B. Fat-Soluble Vitamins 1. The factors that affect fat-soluble vitamin absorption are __________________ __________________________________________________________________ 2. Fat-soluble vitamins are stored ___________________________________ and cooking/food processing ______________________________________________ 3. Vitamin A is synthesized from ___________________________________ and is stored in _________________________________________________________ 4. Vitamin A is stable in __________________________________________ and unstable in _________________________________________________________ 18-6 5. Functions of vitamin A are _________________________________________ __________________________________________________________________ 6. Sources of vitamin A are ___________________________________________ __________________________________________________________________ 7. Excess vitamin A produces _________________________________________ ____________________ and a deficiency produces _______________________ __________________________________________________________________ 8. Vitamin D is a group of _________________________________________ and is stored ___________________________________________________________ 9. Vitamin D is resistant to ___________________________________________ 10. The functions of vitamin D are _____________________________________ __________________________________________________________________ 11. Sources of vitamin D are __________________________________________ __________________________________________________________________ 12. An excess of vitamin D produces ___________________________________ _____________________ and a deficiency produces ______________________ __________________________________________________________________ 13. Vitamin E is stored in ____________________________________________ 14. Vitamin E is resistant to ________________________________________ and __________________________________________________________________ 15. Functions of vitamin E are _________________________________________ __________________________________________________________________ 16. Sources of vitamin E are __________________________________________ __________________________________________________________________ 17. An excess of vitamin E produces _________________________________ and a deficiency produces ________________________________________________ 18. Vitamin K is resistant to _______________________________________ and Destroyed by _______________________________________________________ 19. Vitamin K is stored _______________________________________________ 20. Functions of vitamin K are ________________________________________ __________________________________________________________________ 18-7 21. A deficiency of vitamin K produce __________________________________ __________________________________________________________________ 22. Sources of vitamin K are __________________________________________ __________________________________________________________________ C. Water-Soluble Vitamins 1. Thiamine is vitamin _______ and is destroyed by _______________________ 2. The functions of thiamine are _______________________________________ __________________________________________________________________ 3. Sources of thiamine are ____________________________________________ __________________________________________________________________ 4. Deficiencies of thiamine produce ____________________________________ __________________________________________________________________ 5. Riboflavin is vitamin ________, is stable to _________________________ and unstable in _________________________________________________________ 6. The functions of riboflavin are ______________________________________ __________________________________________________________________ 7. Sources of riboflavin are ___________________________________________ __________________________________________________________________ 8. Deficiencies of riboflavin produce ____________________________________ 9. Niacin is stable in ______________________________________________ and is synthesized from __________________________________________________ 10. The functions of niacin are ________________________________________ __________________________________________________________________ 11. Sources of niacin are _____________________________________________ __________________________________________________________________ 12. An excess of niacin produces _______________________________________ __________________________________________________________________ And a deficiency produces ____________________________________________ 13. Pantothenic acid is destroyed by ____________________________________ 14. The functions of pantothenic acid are ________________________________ __________________________________________________________________ 18-8 15. Sources of pantothenic acid are _____________________________________ __________________________________________________________________ 16. Vitamin B6 is stable in _________________________________________ and unstable in _________________________________________________________ 17. The functions of vitamin B6 are _____________________________________ __________________________________________________________________ 18. Sources of vitamin B6 are _________________________________________ __________________________________________________________________ 19. An excess of vitamin B6 produces ___________________________________ __________________________________________________________________ 20. Cyanocobalamin is vitamin _________ and is stable in __________________ __________________________________________________________________ 21. The absorption of cyanocobalamin is regulated by ______________________ 22. The functions of cyanocobalamin are ________________________________ __________________________________________________________________ 23. Sources of cyanocobalamin are _____________________________________ __________________________________________________________________ 24. A deficiency of cyanocobalamin produces ____________________________ __________________________________________________________________ 25. Folacin is unstable in __________________________________________ and is stored __________________________________________________________ 26. The functions of folacin are ________________________________________ __________________________________________________________________ 27. Sources of folacin are_____________________________________________ __________________________________________________________________ 28. A deficiency of folacin produces ____________________________________ __________________________________________________________________ 29. Biotin is stable in _____________________________________________ and unstable in _________________________________________________________ 30. The functions of biotin are _________________________________________ __________________________________________________________________ 18-9 31. Sources of biotin are _____________________________________________ __________________________________________________________________ 32. Ascorbic acid is vitamin _________ and is stable in _____________________ _________________ but unstable in ___________________________________ 33. Functions of ascorbic acid are ______________________________________ __________________________________________________________________ 34. Sources of ascorbic acid are ________________________________________ __________________________________________________________________ 36. A deficiency of ascorbic acid produces _______________________________ __________________________________________________________________ VIII. Minerals A. Introduction 1. Minerals are _____________________________________________________ 2. Minerals are usually extracted from ______________________________ , and humans obtain them by _______________________________________________ B. Characteristics of Minerals 1. Minerals are responsible for_________________________ of body weight and are most concentrated in ______________________________________________ 2. The minerals______________________________________ are very abundant in bones and teeth. 3. Minerals are usually incorporated into ________________________________ 4. Minerals compose parts of __________________________________________ 5. Other functions of minerals are ______________________________________ __________________________________________________________________ 6. The physiologically active form of minerals is __________________________ 18-10 C. Major Minerals 1. ___________________________________ are the most abundant of the major minerals accounting for_______________________________________________ 2. Other major minerals are ___________________________________________ __________________________________________________________________ 3. Calcium is primarily distributed _____________________________________ __________________________________________________________________ 4. Functions of calcium are ___________________________________________ __________________________________________________________________ 5. Sources of calcium are _____________________________________________ __________________________________________________________________ 6. A calcium deficiency in children causes _______________________________ ______________________________________________ and in adults may cause __________________________________________________________________ 7. Phosphorus is primarily distributed ___________________________________ __________________________________________________________________ 8. Functions of phosphorus are ________________________________________ __________________________________________________________________ 9. Sources of phosphorus are __________________________________________ __________________________________________________________________ 10. Potassium is distributed ___________________________________________ __________________________________________________________________ 11. Functions of potassium are ________________________________________ __________________________________________________________________ 12. A deficiency of potassium produces _________________________________ __________________________________________________________________ 13. Sources of potassium are __________________________________________ __________________________________________________________________ 14. Sulfur is distributed ______________________________________________ __________________________________________________________________ 15. Functions of sulfur are ____________________________________________ 18-11 __________________________________________________________________ 16. Sources of sulfur are _____________________________________________ 17. Sodium is distributed _____________________________________________ __________________________________________________________________ 18. Functions of sodium are ___________________________________________ __________________________________________________________________ 19. An excess of sodium produces _________________________________ and a Deficiency produces _________________________________________________ 20. Sources of sodium are ____________________________________________ __________________________________________________________________ 21. Chlorine is distributed ____________________________________________ __________________________________________________________________ 22. Functions of chlorine are __________________________________________ __________________________________________________________________ 23. Sources of chlorine are____________________________________________ __________________________________________________________________ 24. Magnesium is distributed __________________________________________ __________________________________________________________________ 25. Functions of magnesium are _______________________________________ __________________________________________________________________ 26. An excess of magnesium produces _____________________________ and a deficiency produces _________________________________________________ 27. Sources of magnesium are _________________________________________ __________________________________________________________________ D. Trace Elements 1. Trace elements are ________________________________________________ 18-12 2. Examples of trace elements include ___________________________________ __________________________________________________________________ 3. Iron is distributed in _______________________________________________ __________________________________________________________________ 4. Functions of iron are ______________________________________________ __________________________________________________________________ 5. Sources of iron are ________________________________________________ __________________________________________________________________ 6. An excess of iron produces ____________________________________ and a deficiency produces _________________________________________________ 7. Manganese is distributed ___________________________________________ __________________________________________________________________ 8. Functions of manganese are _________________________________________ __________________________________________________________________ 9. Sources of manganese are __________________________________________ __________________________________________________________________ 10. Copper is distributed _____________________________________________ __________________________________________________________________ 11. Functions of copper are ___________________________________________ __________________________________________________________________ 12. Sources of copper are _____________________________________________ __________________________________________________________________ 13. Iodine is concentrated in __________________________________________ 14. Functions of iodine are____________________________________________ 15. Sources of iodine are _____________________________________________ __________________________________________________________________ 16. An excess of iodine produces _________________________________ and a deficiency produces _________________________________________________ 17. Cobalt is _____________________________________________ distributed. 18. Functions of cobalt are ____________________________________________ __________________________________________________________________ 18-13 19. Sources of cobalt are _____________________________________________ __________________________________________________________________ 20. An excess of cobalt produces __________________________________ and a deficiency produces _________________________________________________ 21. Zinc is distributed _______________________________________________ 22. Functions of zinc are _____________________________________________ __________________________________________________________________ 23. Sources of zinc are _______________________________________________ __________________________________________________________________ 24. An excess of zinc produces ___________________________________ and a deficiency produces _________________________________________________ 25. Fluorine is distributed _____________________________________________ 26. Functions of fluorine are __________________________________________ 27. Sources of fluorine are ____________________________________________ 28. An excess of fluorine produces _____________________________________ 29. Selenium is distributed ____________________________________________ 30. Functions of selenium are _________________________________________ 31. Sources of selenium are ___________________________________________ 32. An excess of selenium produces ____________________________________ 33. Chromium is distributed __________________________________________ 34. Functions of chromium are ________________________________________ 35. Sources of chromium are __________________________________________ IX. Healthy Eating – The Food Pyramid and Reading Labels A. Introduction 1. An adequate diet provides __________________________________________ __________________________________________________________________ 2. It is not possible to design one diet for everyone because __________________ __________________________________________________________________ 3. RDA stands for __________________________________________________ 4. RDA values are set _______________ because _________________________ __________________________________________________________________ 18-14 B. Malnutrition 1. Malnutrition is _______________________ that results from ______________ __________________________________________________________________ 2. Undernutrition is ___________________________________ and overnutrition is ________________________________________________________________ 3. Primary malnutrition is ____________________________________________ 4. Secondary malnutrition is __________________________________________ __________________________________________________________________ C. Starvation 1. Introduction a. A healthy person can stay alive for __________________ without food. b. Starvation is seen in _________________________________________ ____________________________________________________________ c. After one day without eating, the body ___________________________ ____________________________________________________________ d. By the third day of starvation, _________________________________ ____________________________________________________________ e. Gradually during starvation, metabolism ___________________ , blood pressure, __________________, the pulse ______________________ , and _______________________________________________________ set in. f. Eventually skin becomes dry and hair falls out because _____________ ____________________________________________________________ 18-15 g. Near the end of starvation, the human is _________________________ ____________________________________________________________ 2. Marasmus and Kwashiorkor 1. Marasmus is _______________________________________________ 2. Children under the age of two with marasmus often die of ___________ ____________________________ because ________________________ 3. Kwashiorkor is characterized by ____________________________ and develops when ________________________________________________ ____________________________________________________________ 4. Ascites is _________________________________________________ ____________________________________________________________ 3. Anorexia Nervosa a. Anorexia nervosa is _________________________________________ b. Anorexia nervosa is most common in ___________________________ ____________________________________________________________ c. Treatments of anorexia nervosa are _____________________________ ____________________________________________________________ 4. Bulimia a. Bulimia is a condition in which ________________________________ ____________________________________________________________ b. A dentist is sometimes the first to spot a person with bulimia because ____________________________________________________________ X. Life-Span Changes A. Throughout life, dietary requirements ___________________________________ but the ability to _____________________________________________________________ B. Changing nutrition with age often reflects ___________________________________ ________________________________________________________________________ C. Medical conditions that affect the ability to obtain adequate nutrition are ___________ ________________________________________________________________________ D. The BMR rises ____________________ and declines _________________________ 18-16