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Chapter Objectives: Chapter 44-45 Maintaining Homeostatsis 1. Distinguish between osmoregulators and osmoconformers 2. Discuss the problems that marine organisms, freshwater organisms, and terrestrial organisms face in maintaining homeostasis and explain what osmoregulatory adaptations serve as solutions to these problems 3. Explain the role of transport epithelia in osmoregulation 4. Describe how a flame-bulb (protonephridia) excretory system functions 5. Explain how the metanephridial excretory tubule of annelids functions and describe any structural advances over a protonephridial system 6. Explain how the Malpighian tubule excretory system contributed to the success of insects in the terrestrial environment 7. Using a diagram, identify and give the function of each structure in the mammalian excretory system 8. Using a diagram, identify and give the function of each part of the nephron 9. Describe and show the relationship among the processes of filtration, secretion, and reabsorption 10. Explain the significance of the fact that juxtamedullary nephrons are only found in birds and mammals 11. Explain how the loop of Henle enhances water conservation by the kidney 12. Describe the mechanisms involved in the hormonal regulation of the kidney 13. Describe structural and physiological adaptations in the kidneys of nonmammalian species that allow them to osmoregulate in different environments 14. Explain the correlation between type of nitrogenous waste produced (ammonia, urea, or uric acid) by an organism and its habitat 15. Describe the adaptive advantages of endothermy 16. Discuss 4 general categories of physiological and behavioral adjustments used by land mammals to maintain relatively constant body temperatures 17. Distinguish between the 2 thermoregulatory centers of the hypothalamus 18. Describe the thermoregulatory adaptations found in non-terrestrial animals 19. Describe several mechanisms of physiological acclimatization to new temperature ranges 20. Distinguish between hibernation and aestivation *********************** 21. Compare the response times of the 2 major systems of internal communication (nervous and endocrine systems) 22. Distinguish among types of chemical messengers (structural and functional differences) 23. Distinguish between endocrine and exocrine glands 24. Describe the relationships among endocrine system components: a. hormones 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. b. endocrine glands c. target cells d. target cell receptors List the general chemical classes of hormones and give examples of each Explain how pheromone function differs from hormone function Provide indirect evidence that humans may communicate with pheromones State which of the 2 classes of hormones is lipid soluble and explain how this property affects hormone function Describe the mechanism of steroid hormone action and explain the location and role of steroid hormone receptors Explain how to account for specificity in target cell response to hormonal signals Compare and contrast the 2 general modes of hormone action Describe hormonal regulation of insect development including the roles of ecdysone, brain hormone, and juvenile hormone Describe the location of the hypothalamus and explain how its hormonereleasing cells differ from both endocrine gland secretory cells and other neurons Describe the location of the pituitary and explain the functions of the posterior and anterior lobes List the posterior pituitary hormones and describe their effects on target organs Using antidiuretic hormone as an example explain how a hormone contributes to homeostasis and how negative feedback can control hormone levels Define tropic hormone and describe the functions of tropic hormones produced by the anterior pituitary Explain how the anterior pituitary is controlled List hormones of the thyroid gland and explain their role in development and metabolism Diagram the negative feedback loop which regulates the secretion of thyroid hormones State the location of the parathyroid glands and describe hormonal control of calcium homeostasis Distinguish between alpha and beta cells in the pancreas and explain how their antagonistic hormones (insulin and glucagon) regulate carbohydrate metabolism List hormones of the adrenal medulla, describe their function, and explain how their secretion is controlled List hormones of the adrenal cortex, describe their function, and explain how their secretion is controlled Describe short-term and long-term endocrine responses to stress Identify male and female gonads and list the 3 categories of gonadal steroids Define gonadotropin and explain how estrogen and androgen synthesis is controlled 48. Describe the location of the pineal and thymus glands, list their hormone products, and describe their functions 49. Explain how the endocrine and nervous systems are structurally, chemically, and functionally related Chapter Terms: Chapter 44 Terms thermoregulation transport epithelium nephron osmoregulation ammonia glomerulus excretion uric acid Bowman's capsule conduction osmolarity podocytes convection osmoconformer proximal tubule radiation osmoregulator loop of Henle evaporation stenohaline distal tubule ectotherm euryhaline collecting duct endotherm anhydrobiosis cortical nephrons vasodilatation filtration juxtamedullary nephrons vasoconstriction secretion afferent arteriole countercurrent exchange reabsorption efferent artriole exchanger protonephridium peritubular capillaries nonshivering metanephridium vasa reta thermogenesis Malpighian tubules antidiuretic hormone brown fat renal artery juxtaglomerular apparatus acclimatization renal vein angiotensin II stress-induced proteins ureter aldosterone heat-shock proteins urinary bladder renin torpor urethra renin-angiotensinaldosterone system hibernation renal cortex aestivation renal medulla atrial natriuretic factor Chapter 45 Terms hormone growth hormone (GH) islets of Langerhans target cells insulin-like growth factors alpha cells endocrine system prolactin (PRL) glucagon endocrine glands brain hormone (BH) follicle stimulating hormone beta cells (FSH) insulin luteinizing hormone (LH) type I diabetes mellitus thyroid stimulating hormone (TSH) type II diabetes mellitus juvenile hormone (JH) gonadotropins nitric oxide adrenoorticotropic hormone adrenal cortex (ACTH) adrenal medulla melanocyte stimulating hormone (MSH) epinephrine neurosecretory cells ecdysone growth factors prostaglandins signal-transduction pathways adrenal glands endorphins norepinephrine pineal gland catecholamines melatonin corticosteroids thyroid gland glucocorticoids triiodothyronine (T3 ) mineralocorticoids thyroxine (T4) androgen calcitonin testosterone tropic hormones hypothalamus pituitary gland anterior pituitary releasing hormones inhibiting hormones parathyroid glands estrogen posterior pituitary parathyroid hormone (PTH) progestins pancreas Chapter Outline Framework A. Regulation of Body Temperature 1. 4 physical processes account for heat loss or gain 2. Ectotherms derive body heat mainly from surroundings and endotherms derive body heat mainly from metabolism 3. Thermoregulation involves physiological and behavioral adjustments 4. Most animals are ectothermic but endothermy is widespread 5. Torpor conserves energy during environmental extremes B. Water Balance and Waste Disposal Water balance and waste disposal depend on transport epithelia Animal nitrogenous wastes are correlated with phylogeny and habitat Cells require balance between osmotic gain and loss of water Osmoregulators expend energy to control their internal osmolarity; osmoconformers are isoosmotic with their surroundings Excretory Systems 1. Most excretory systems produce urine by refining a filtrate derived from body fluids 2. Diverse excretory systems are variations on a tubular theme 3. Nephrons and associated blood vessels are the functional units of the mammalian kidney 4. From blood filtrate to urine 5. Mammalian kidney's ability to conserve water is a key terrestrial adaptation 6. Nervous and hormonal feedback circuits regulate kidney function 7. Diverse adaptations of the vertebrate kidney have evolved 8. Interacting regulatory systems maintain homeostasis Introduction to Regulatory Systems 1. Endocrine system and nervous system are structurally, chemically, and functionally related 2. Invertebrate regulatory systems clearly illustrate endocrine and nervous system interactions Chemical Signals and their Modes of Action 1. Variety of local regulators affect neighboring target cells 2. Chemical signals bind to specific receptor proteins within target cells or on their surface 3. Most chemical signals bind to plasma membrane proteins initiating signal-transduction pathways 4. Steroid hormones, thyroid hormones, and some local regulators enter target cells and bind with intracellular receptors Vertebrate Endocrine System 1. Hypothalamus and pituitary integrate many functions of the vertebrate endocrine system 2. Pineal gland is involved in biorhythms 3. Thyroid hormones function in development, bioenergetics, and homeostasis 4. Parathyroid hormone and calcitonin balance blood calcium 5. Endocrine tissues of the pancreas secrete insulin and glucagon, antagonistic hormones that regulate blood glucose 6. Adrenal medulla and adrenal cortex help the boy manage stress 7. Gonadal steroids regulate growth, development, reproductive cycles, and sexual behavior 1. 2. 3. 4. C. D. E. F.