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Marina Alamanou BSc, PhD
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Cellular and Molecular biologist with over 12 years of experience in academia, start-up companies and multinationals
Professional experience spans a wide range of areas: Cancer research. Preclinical drug development. Biomarker
discovery research. In vitro diagnostics industry experience. Clinical project management
Biomedical areas of expertise include oncology, bone biology, oxidative stress mechanisms, RNA metabolism and
angiogenesis inhibitor-related toxicities
Strong experience in start up environments. Business development: creation of white papers, brochures, technical data
sheets, and commercialization plans during new business development
Writing technical documentation: scientific publications, review manuscripts, abstracts, grant proposals, detailed and
summarized project progress reports. Authoring posters and power point presentations. Presented results at in-house
and extramural scientific meetings
Skilled at initiating, administrating and executing across a portfolio of projects harmonizing technical needs with
business realities: conceptualization, budgeting, estimation, planning, mentoring, development and testing
Qualifications
 PhD in Cellular and Molecular Biology (area: biomarker discovery)
 Bachelor of Biological Sciences
Related Experience
 Project Management (managing complex multifunctional projects)
 Budget Management (for start ups)
 People Management. Training Management. Technology and Knowledge Transfer (articulate communicator fluently
speaking the language of both people and technology)
 Cross functional coordination
Professional experience
Life Science Consultant
12/2015 – today
Solutions throughout product development
Freelancer
 Facilitating activities of the research teams, study design, writing project proposals and developing and implementing
budgets. Preclinical and Clinical Development Programs & Study Design
Achievements
 Planed, directed, and coordinated activities of designated preclinical and clinical studies to ensure that goals or
objectives of project are accomplished within prescribed time frame and funding parameters by performing the duties
personally or through project team members
Product development Scientist
01/2015 – 09/2015
Development of molecular diagnostic assays
DiaSorin Ltd, Dublin, Ireland
 Member of the technology transfer team: process scale-up, process validation and manufacturing for successful
process validation and commercialization of LAMP technology
 Review documentation for new product introduction (NPI). Support R&D in preparation of DHFs and Technical Files to
ensure products meet regulatory requirements
Achievements:
 Ability to set-up appropriate communication channels between functional units at donor and receiving sites to facilitate
right first time technology and knowledge transfer
Sabbatical break from career
12/2013 – 12/2014
Travelling (Canada, Europe) and taking online courses (www.coursera.org) related to management; drug discoverydevelopment and commercialization; innovation and commercialization; brand management: aligning business, brand and
behaviour, start up funding for entrepreneurs, investment, business analysis
Experienced Scientist (Marie Curie)
11/2011 – 11/2013
In a EU-supported project (AngioTox) between SMEs, Academia, Bayer and Roche
OncoMark Ltd, Nova UCD Dublin, Ireland
 Managed the histology facility of the start-up company and preparing preclinical reports (Pathology Experts GmbH)
 Assisted the CEO with marketing strategies and plans: preparing white papers, technical data sheets and brochures.
Preparing business plans during engagement with the venture capital community
 Assisted the CEO in intellectual property (IP) negotiations. Applied staged-gate principals to research and validation of
patent claims during technical development of the Intellectual Property portfolio of the Company
 Ability to set-up appropriate communication channels between: scientific advisors/consultants and potential corporate
partners
Achievements:
 Initiated a collaborative relationship between OncoMark Ltd and clinicians regarding angiogenesis inhibitors currently in
clinical trials for the identification/ verification of novel biomarkers of toxicity for the development of new cancer
diagnostic tests
Senior Scientist/ Lab manager
Genomic Screening Laboratory
04/2008 – 04/2011
CIBIO, Trento, Italy
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Overall planning and developing of new research projects, timetable management and coordination of scientific work,
budget management: from start through to completion
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Responsible for costing, estimating and planning projects. Tracking activities against the detailed project plans
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Updated project plans to include agreed changes. Producing accurate financial reports
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Managerial duties included: scheduling staff, reordering supplies, and maintaining security standards, responsibility for
all equipment, software, and documentation. Preparation and submission of grant proposals.
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Designed and supervised high-throughput screening studies for the identification of novel drug targets (breast cancer)
Achievements:
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Setting up a laboratory and common spaces (facilities) in a start-up environment: organizing workspace and
instrument selection, install, assemble, operate, manage and maintain instrumental apparatus and equipment.
Involvement in the purchase of consumables and liaising with approved suppliers
Post Doc
03/2005 – 03/2008
Bone Homeostasis Laboratory
University of L’Aquila, Italy
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Designed, conducted and supervised studies evaluating the effect of small peptides on bone homeostasis including:
preparation, sampling, data collection and analysis and preparation of results and reports
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Planned and development of preclinical in vitro and in vivo studies with drugs of Novartis Pharma
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Presented results at in-house and extramural scientific meetings
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Prepared abstracts, posters and slide presentations for congress symposia and posters
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Achievements:
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Discovery of the molecular mechanism of action of PRELP peptide
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Designed, conducted and supervised studies during preclinical product development (small molecules, and peptides)
Facilities Management roles
 OncoMark Ltd, Dublin, Ireland: headed the histology facility of the start-up company and as such coordinated its
activities as a service provided to outside users (2011-2013)
 Cibio/ University of Trento, Italy: headed the set up of a new laboratory (for conducting Genomic Screening) and
common spaces (proteomics, genomics and microscopy facilities) in a start-up environment (2008-2011)
 Cibio/ University of Trento, Italy: headed the microscopy facility of the start up institute (2008-2011) and as such
coordinated its activities as a service provided to scientists in other departments
 Department of Experimental Medicine, University of L’Aquila, Italy: headed the microscopy facility of the institute and
the histology unit of my laboratory, managed junior staff members and trained students and staff in microscopy
laboratory procedures (2006-2008)
 Department of Applied Biology, University of L’Aquila Italy: Serving as Biosafety Officer. I was part of a team
responsible for the coordination of health and safety instructions and university policies and procedures (2000-2004)
Other competencies
Languages
 Greek - Native
 English - Fluent in speaking, writing, reading (First Certificate in English-FCE from University of Cambridge in England)
 Italian - Fluent in speaking, writing, reading
Business Software, Hardware
 Systat Sigmaplot, Adobe Photoshop, ImageJ, IBM SPSS, DesignExpert, Data analysis tools for life sciences
 MS Office
Process Know-how
 Project Management. Budget Management
 Design (preclinical and clinical studies, biomarker discovery, companion diagnostics assays)
 Types of products (Small molecules, Peptides, Molecular diagnostics, Immunoassays, Microarrays, Imaging)
 Training Management (mentoring and training regarding technology use)
 Technology and Knowledge Transfer and Validation
 Design dossier (testing reports, clinical evaluations, risk management assessments)
Equipment Know-how
 Laboratory
 Manufacture site (batch, production)
 Packaging
Education and training
University
 University of L’Aquila, PhD. Cellular and Molecular Biology (Italy) (2000-2004)
 University of L’Aquila BSc of Biological Sciences (Italy) (1994-2000, five yrs course)
Personal details
Contact Details: Email: [email protected], Phone: 00353 (0) 87 935 7851, Skype ID: biomarinium76
Nationality: Greek, Date of Birth: 31/05/1976