Download Discussion Guide Chapter 11

Discussion Guide Chapter 9
Mader 10th edition
1. Below is a list of the phases of the cell cycle. Write a brief description of what occurs in
each phase.
(a) G1 _______________________________________________________________
(b) S________________________________________________________________
(c) G2_________________________________________________________________
(d) M__________________________________________________________________
(e) C __________________________________________________________________
2. How does interphase fit into this cell cycle organization listed above?
3. Biologists used to believe that interphase was a “resting period” during the life cycle of
the cell. Why did this appear to be so? What do we now consider interphase to be?
Go to http://www.nobel.se/medicine/educational/2001/cellcycle.html
4. What is the G1/S checkpoint and where does it fit into the cell cycle?
5. What cell conditions are being monitored at the G1/S checkpoint?
6. What is the G2/M checkpoint and where does it fit into the cell cycle?
7. What cell conditions are being monitored at the G2/M checkpoint?
8. What is the spindle checkpoint and where does it fit into the cell cycle?
9. What cell conditions are being monitored at the spindle checkpoint?
10. Why is the regulation of the cell cycle critical to normal function in the multicellular
organism?
11. For each of the following, takes notes about what type of molecule they are and their role
in the cell cycle.
a. Cdk’s
b. cyclins
c.
growth factors
d. p53
12. Define the following terms.
a. haploid
b. diplid
c.
histones
d. chromatin
e. centromere
f.
chromatid
13. Label the following diagram with chromatid, centromere, kinetochore, sister chromatids
14. Complete the chart on mitosis.
Phase
Prophase
Prometaphase
Metaphase
Anaphase
Telophase
Diagram
Description
12. Colchicine is a poison that binds to tubulin and prevents its assembly into microtubules;
cytochalasins are compounds that bind to the ends of actin filaments and prevent their
elongation. What effects do you think these two substances would have on cell division
in animal cells?
13. How is cytokinesis in animal cells different from that in plant cells?
14. Compare and contrast reproductive cloning with therapeutic cloning.
15. What are 6 characteristics of cancer?
16. How do proto-oncogenes differ from tumor-suppressor genes in the mechanisms by
which they lead to excessive cell proliferation and cancer?
17. How does a prokaryotic chromosome differ from a eukaryotic chromosome?
18. How does binary fission differ from mitosis?