Download Mitosis Internet Lab

Name_____________________________________ Date________ Points __________
Cellular Reproduction Internet Labs (Cell Cycle, Mitosis, Cancer and Meiosis)
Directions: You will complete this web quest in 2 different visits to the computer lab. Anything not completed
in class is due for homework.
Part One: Controlling the Cell Cycle Game
This first game is to introduce and familiarize you with the stages of the cell cycle. You must go through all of
the steps of this game. If your cell is destroyed you must try again. Pay close attention to the cell cycle clock
and it will help you control the cell cycle. You do not have to answer any questions.
http://www.nobelprize.org/educational/medicine/2001/cellcycle.html
Part Two: Cell Cycle & Mitosis
Introducing the Cell cycle: Go to the following URL: http://www.cellsalive.com
On the left hand side of the screen, Click on the Cell Cycle link and watch the animation then answer the
questions.
1. How is the cell cycle defined? _____________________________________________________
2. What is the longest period of the cell cycle? ______________________________________________
3. How long does Interphase last in mammal tissue cells? ____________________
4. What is being synthesized and produced during Interphase?
5. What are the 3 stages of Interphase? ____________, ____________, ______________
6. What happens in G1? _____________________________________________________
7. What happens in S? _____________________________________________________
8. What Happens in G2? _____________________________________________________
9. If a cell stays in G0 what does that mean? _______________________________________
** On the animation Turn on the Check points.
10. What happens in the G1 check point? __________________________________________
11. What occurs in the G2 checkpoint? ____________________________________________
12. Define Cyclin _____________________________________________________________
Now locate the green link “Mitosis” under the “Interactive…” heading. Click on the “Mitosis” link. Play the
animation and go through all of the stages of Mitosis in an animal cell.
Answer the following questions from this page:
1. The first stage of Mitosis is Prophase, what is happening to the nucleolus during this stage?
_______________________________________________
2. Define chromatin: _________________________________________________________
3. When a chromosome replicates, it is composed of two sister ____________
4. Describe Prometaphase? ___________________________________________________
5. Where do the spindle fibers attach to the chromosome? ________________________
6. Describe Metaphase? ___________________________________________________
7. Spindle fibers _________________________ and pull chromatids to opposite sides of the cell during
what phase? ______________________________
8. The last stage of mitosis is ______________________, and is when the daughter
____________________________ have arrived at opposite poles of the cell.
9. When does Cytokinesis occur? _____________________________________________
10. What happens in animal cells during Cytokinesis? _______________________________
Part Three Mitosis
Use the following URL below to complete the stages of mitosis worksheet.
http://www.biology.arizona.edu/cell_bio/activities/cell_cycle/activity_description.html
INTERPHASE
1. What happens to the DNA during this phase? _____________________________
2. Distinct chromosomes are not visible. What are uncoiled chromosomes referred to as in this phase?
_____________________________________________________
3. How many stages are in the cell cycle? (BE CAREFUL!) ______________________
4. Is Interphase part of Mitosis? __________________
5. What other structure is visible in the nucleus of the cell during interphase? _______
PROPHASE
1. Prophase is the ____ (a #)phase of mitosis and the _____ (a #) stage of the cell cycle.
2. ______________ condenses and becomes distinct chromosomes.
3. The nuclear membrane _______________.
4. Centrioles begin to move to _________ sides and spindle fibers form between them.
METAPHASE
1. Where do the chromosomes align themselves during this phase? _________________
2. The aligning of the _________________ helps to ensure that in the next phase, when the chromosomes
are separated, each new _____________ will receive one copy of each chromosome.
ANAPHASE
1. The chromosomes are pulled apart at their centromeres as the spindle gets ________.
TELOPHASE
1. The nuclear membrane _____________ and the chromosomes uncoil to form ___________________.
CYTOKENESIS
1. The division of the __________________ occurs at the end of the cell cycle.
2. _________ (a #) new identical daughter cells form.
Click Next to begin the Onion Root Tip Lab. You are to place each drawing into one of the 5 phases. Keep
tally marks in the table below of the number of cells you find in each stage. Then list what percentage of cells
there is in each stage.
Interphase
Prophase
Metaphase
Anaphase
Telophase
Total
# of cells
36
% of cells
100%
% of Cells Calculation:
II.
# of cells counted in each phase X 100 = _______
36
Use the following URL to complete the next part of the lab.
http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/cells3.html
1. Read the tutorial then click NEXT. You will be on the Cell Cycle and Mitosis Tutorial. Each
number has a problem/question for you to answer. Only answer the numbers I have listed.
2. Click on cell cycle stages and answer the following questions below.
#1 _____ #3 _____#4 _____#6 _____#7 _____#8 _____#10 _____
Part Four: CANCER WEBQUEST
1. Click on this link from Nova and watch how Cancer Grows.
http://www.pbs.org/wgbh/nova/cancer/grow_flash.html
Go to http://www.insidecancer.org
Click on Hallmarks of Cancer, then click on each of the tabs to the left to answer the questions below.
CANCER OVERVIEW:
1. Where can cancer, or tumors, occur in the body? ___________________________________________
2. Solid tumors form _______________, while liquid tumors ____________________________________.
3. How do cancers start? ___________________________________________________
4. What percent of cancers are genetically inherited? _____________
5. As we age, we accumulate more and more mutations. What does this explain?
________________________________________________________________________________________
GROWING UNCONTROLLABLY:
6. How or why do cancer cells grow?
7. What do cancer cells have to learn how to grow without?
____________________________________________
8. What do cancer cells have to learn how to grow in the presence of?
__________________________________
EVADING DEATH:
9. How do cancer cells avoid death?
10. What is apoptosis?
PROCESSING NUTRIENTS:
11. How do cancer cells survive? What must they take in and attract?
BECOMING IMMORTAL:
12. The age of a cell and its ability to divide is related to what? Explain.
13. What do telomeres do and how does this relate to cancer?
14. Explain how telomerase enables cancer cells.
INVADING TISSUES:
15. What are 90% of human cancers due to?
AVOIDING DETECTION:
16. What are the two parts to adaptive immune responses?
PROMOTING MUTATIONS:
17. What affects the development of cancer cells?
18. What is genomic instability?
19. Name 2 ways in which we accumulate changes in our genes that can cause cancer?
Click on the CAUSES & PREVENTION section and answer the following questions.
20. What percent of cancer does pollution, food additives, and industrial wastes have an effect on?
21. Choose 2 of the tabs to the left to research forms of cancer. Read the information and describe the
types of cancer caused by each. SMOKING, INHERITANCE, DIET, MOLD, VIRUSES, SUNLIGHT
Part Five: MEIOSIS
Go to the following URL: http://www.cellsalive.com
Click on the green “Meiosis” link on the left hand side of the page.
Answer the following questions or complete the statements from the Meiosis page.
1. Chromosomes duplicate to form ___________________
2. What forms from the beginning process of cytokinesis at the end of Meiosis I? ___________________
3. How do spindle fibers move the chromosomes to the equator of the cell?
____________________________________________________________________________
4. Which phase results in chromatids splitting and moving towards opposite ends of the cell? __________
5. How many chromosomes are present in a gamete? ___________________
6. How many chromosomes are present if two gametes fuse? ___________________
7. What is a zygote? _________________________________________________________
Meiosis Internet Lab
Go to the following URL: http://biology.arizona.edu/default.html Click on Biology Project. Click on the blue
Cell Biology. Once on the next page, find the blue Meiosis and click on it. Click on Reproduction to complete
the table.
Compare and contrast asexual and sexual reproduction.
Questions
Asexual reproduction
Sexual reproduction
What type of cell division?
Mitosis or Meiosis
(circle one)
Mitosis or Meiosis
(circle one)
How many parents?
One or Two
(circle one)
One or Two
(circle one)
Type of offspring.
A clone of the original cell is
produced.
A zygote with two sets of
chromosomes is produced.
1. What is meiosis?
_______________________________________________________________
_______________________________________________________________
_______________________________________________________________
Go to the bottom and click PREVIOUS. Once at the main page click Chromosomes in a diploid cell.
1.
What symbol means diploid? ______________
2.
What is the diploid number of chromosomes for humans? ________________
3.
What is the symbol for haploid? _____________
4.
What is the haploid number of chromosomes for humans? ________________
5.
How many sets of autosomes or body cells do humans have? ______________
6.
How many sets of sex chromosomes do humans have? ___________________
7.
What are the female sex chromosomes? ______________________________
8.
What are the male sex chromosomes? _______________________________
Go to the bottom and click PREVIOUS. Now go to Meiosis I. Click it.
The Phases of Meiosis I and II. List what is occurring during each phase. You can use your notes to help
complete this section.
Prophase I
Prometaphase is a combination of late prophase and early metaphase.
Metaphase I
Anaphase I
Telophase I and
Cytokenesis
Now click the Meiosis I Animation and view what exactly is happening. After viewing Meiosis I, view Meiosis II.
Use your notes if you cannot remember the answer.
1.
At the end of Meiosis I, how many cells have formed? __________________
2.
At the end of Meiosis II, how many cells have formed? __________________
3. How is Meiosis II different from Mitosis?
______________________________________________________________
______________________________________________________________
______________________________________________________________
Scroll down to the bottom of the page and click Main page of the tutorial. Click Meiosis II.
**NOTE** Bivalent means tetrad.
4. Compare and Contrast Mitosis and Meiosis.
Meiosis
Chromosome behavior
1.
Mitosis
Chromosome behavior
1.
Chromosome number
2.
Chromosome number
2.
Genetic identity
3.
Genetic identity
3.
Scroll down to the bottom of the page and click Main page of Tutorial. Click Test Yourself.
Meiosis – Test Yourself
Under Test Yourself answer the questions for better understanding. Click on the blue topic and the questions
will appear. Answer the question by clicking on the correct letter. You will get immediate feedback on your
answer. Also answer the questions in the blanks provided below. When you have answered all questions put
this completed web quest in your folder.
1. ______
6. ______
2. ______
7. ______
3. ______
8. ______
4. ______
9. ______
5. ______
10. ______
Part Six: EXTRA Challenge
When you Finish this web quest Here are some extra reviews and games to make sure that you understand
the Cell Cycle, Mitosis, Meiosis and Cancer.
1. Meiosis Animation: On this site click on of the links for Meiosis for a great review on all of the steps.
http://highered.mcgraw-hill.com/sites/9834092339/student_view0/chapter11/how_meiosis_works.html
2. Crossing Over in Meiosis: this is why we have genetic variation. Check out the animations to get a
could explanation. http://www.zerobio.com/crossing_over.htm
3. More Crossing over and genetic recombination. This is also when chromosome mutations occur.
http://www.csuchico.edu/~jbell/Biol207/animations/recombination.html
4. Complete the online interactive Biology Lab for Mitosis. Go all the way through to the Meiosis lab. I use
this in AP Biology but you can handle it quite well.
http://www.phschool.com/science/biology_place/labbench/lab3/intro.html
5. how Cells Divide http://www.pbs.org/wgbh/nova/body/how-cells-divide.html
6. How is Sex Determined http://www.pbs.org/wgbh/nova/body/how-sex-determined.html
7. Vocab Flashcards for Mitosis
http://highered.mcgraw-hill.com/sites/9834092339/student_view0/chapter10/flashcards.html
8. Vocab Flashcards for Meiosis
http://highered.mcgraw-hill.com/sites/9834092339/student_view0/chapter11/flashcards.html
9. Check out all of my games on www.quia.com/pages/cowanhonors.html