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1. Match the underlying pathophysiological mechanism to the disease. ___ 1. destruction of extrapyramidal dopamine neurons a. Amyotrophic Lateral Sclerosis ___ 2. destruction of acetylcholine neurons b. Multiple Sclerosis ___ 3. interruption of blood flow to a portion of the brain c. Stroke ___ 4. meaningless brain activity d. encephalitis ___ 5. central destruction of myelin sheath e. Alzheimer’s Disease ___ 6. progressive paralysis f. Parkinson’s Disease ___ 7. peripheral destruction of myelin sheath g. Guillain Barre Syndrome ___ 8. infection of lining of the brain h. meningitis ___ 9. inflammation of the brain parenchyma i. Epilepsy ___ 10. autosomal dominant induced cognitive loss j. Huntington’s disease 2. Match the medication to its drug class: ___ 1. Tricyclic antibiotic a. Phenobarbital ___ 2. MAO Inhibitor b. amitryptiline (Elavil) ___ 3. SSRI c. Diazepam (Valium) ___ 4. SNRI d. Venlafaxine (Effexor) ___ 5. Atypical Antidepressant e. Zaleplon (Sonata) ___ 6. Typical Antipsychotic f. Risperidone (Risperdal) ___ 7. Atypical Antipsychotic g. Chlorpromazine (Thorazine) ___ 8. Barbiturate h. Nardil ___ 9. Benzodiazepine i. Bupoprion (Wellbutrin) ___ 10. Sedative (Hypnotic) j. Sertraline (Zoloft) 3. What is the most important factor in preventing long term complications of a stroke? a. The location of the stroke b. Time to treatment c. Dose of the thrombolytic d. Type of medication used. 4. What is the most effective drug for parkinson’s disease? a. Levodopa plus carbidopa (Cinemet) b. Cogentin c. Ergot dopamine agonists d. Levodopa 5. Which drug is approved for severe Alzheimer’s disease. a. Aricept (Donazepril) b. Memantine (Namenda) c. Cogentin d. Abilify 6. Which epilepsy drugs work by inhibiting calcium channels? (choose all that apply) a. Phenytoin (Dilantin) b. Ethosuximide (Zarontin) c. Diazepam (Valium) d. Valproic acid (Depakote) 7. What does C in SIGECAPS stand for? a. Have you ever thought you should (C)ut down on alcohol? b. Are you having trouble (C)oncentrating? c. Have you experienced any (C)achexia? d. Are you afraid of getting (C)ancer? 8. Which of the following drugs are used for generalized anxiety disorder? Check all that apply a. Lorazepam (Ativan) b. Buspirone (Bupar) c. Bupoprion (Wellbutrin) d. Paroxetine (Paxil) e. Zolpidem (Ambien) 9. What is Trazadone most commonly used for? a. Depression b. Anxiety c. Insomnia d. Erectile dysfunction 10. When should Zolpidem (Ambien) be administered? a. In the morning b. No later than 4:00 pm c. Two hours before bed time d. As the patient is going to bed. 11. What is a potentially permanent adverse effect of Thorazine, Metoclopramid (Reglan), and Promethazine (Phenergan)? a. Drowsiness b. Tardive Dyskinesia c. Constipation d. Dry mouth and eyes 12. In Schizophrenia, what is a negative symptom? a. A symptom the patient does not want. b. A symptom that is disapproved by society. c. A missing normal behavior d. A symptom that is caused by medications 13. A patient with depression is prescribed Citalopram (Celexa). Three days later, the patient calls back claiming the drug is a miracle and that the depression has been cured. What is the appropriate response by the nurse? a. Advise the patient to continue taking the drug to avoid a relapse. b. Advise the patient to discontinue the drug as it is no longer needed. c. Advise the patient to see their healthcare provider to be evaluated for bipolar disorder. d. Thank God for the miracle and pray with the patient. 14. True or false: Bacterial meningitis is usually not that severe and resolves on its own. a. True b. False 15. Which drug is used for conscious sedation? a. Midzolam (Versed) b. Venlafaxine (Effexor) c. Nortryptiline (Pamelor) d. Phenobarbital 16. What is the immediate purpose of DNA? a. Determine what form life a cell will take. b. Control cellular functions c. Make proteins d. Torture nursing students. 17. Using the format 12345, put the steps of protein synthesis in proper order: 1. synthesis of mRNA 2. binding of amino acids together. 3. matching of mRNA with tRNA 4. binding of mRNA with ribosome 5. unwinding of the chromosome Answer: ________________________ 18. True or false: Many of the genes that we inherit are turned off. a. True b. False 19. A young couple would like to have children, but Huntington’s disease runs in the man’s family. The man tests positive for the gene, what is the best advice for the couple: a. If you have children, all your children will get Huntington’s disease, so you should adopt. b. If you have children, on average, 50% of your children will be carriers. c. If you have children, on average, 25% of your children will have Huntington’s disease. d. If you have children, on average, 50% of your children will have Huntington’s disease. e. Huntington’s disease is Dominant, so the wife should take assertiveness training. 20. What is the defining characteristic of an autosomal recessive disease? a. A gene with a weak allele b. An allele that does not produce a needed protein c. An allele that is overpowered by a dominant allele d. A disease that occurs in timid people. 21. Match the disease/condition to the type of inheritance: ___ 1. Autosomal recessive a. Hemophilia ___ 2. Autosomal dominant b. CAD ___ 3. X linked (Sex linked) c. Huntington’s disease ___ 4. polygenic inheritance d. PKU ___ 5. multifactorial inheritance e. Height 22. AIDS in Africa (Check all that apply) a. Is caused not caused by HIV b. Seems to cause death sooner c. Is transmitted mainly by heterosexual contact d. Has been spread by both war and economic development in cities. 23. The diagnosis of AIDS in the United States requires diagnosis of an AIDS infection and a. CD4 count of <200 b. CD4 count of <400 c. Viral load of >50,000 d. Viral load of >1 million 24. HIV is called a retrovirus. This means that: a. It dresses in clogs and paisely b. It simply takes over a cell to manufacture its DNA c. It simply takes over a cell to manufacture its RNA d. It incorporates its genetic material into the host cell's genome 25. Cells that can be infected by HIV virus include: (check all that apply) a. Cardiac myocytes b. Dendritic cells c. Microglial cells d. Liver cells 26. In addition to treating active HIV infection, AZT can also be used to prevent:(Check all that apply) a. HIV infection after a needle stick b. Herpes outbreaks c. HIV transmission from the mother to the baby during labor d. HIV patients from transmitting it to their sexual partners 27. The main mode of HIV transmission throughout the world is: a. Injecting drug users b. Homosexual sex c. Heterosexual sex d. Blood transfusions