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Infection Control: IV Drug Administration Learning outcomes • Explain the chain of infection and standard precautions. • To understand the application of the chain of infection and standard precautions in relation to IV therapy. • Discuss the actions required to prevent/minimise the risk of infection in a patient receiving IV drug/fluid therapy. • Describe how vascular access device related infections can be detected. Chain of Infection – Administration of IV Therapy Infectious Agent/Organism Susceptible Host Reservoir Means of Entry Means of Exit Route of Transmission Infectious Micro-organisms associated with IV therapy • • • • • • • • Staphylococcus epidermidis Staphylococcus aureus Enterococcus spp. Klebsiella Pseudomonas E. Coli Serratia Candida Reservoirs • Patients Skin – resident microflora • Environment • Equipment • IV Solutions & drugs • HCW Hands -Transient microflora Means of Exit • Secretions such as bodily fluids e.g. blood • Skin such as skin scales Route of Transmission • Direct contact - on healthcare workers hands • Indirect contact- contaminated equipment, fluids, parenteral drugs or infusates • Puncture of skin (inoculation / blood borne) Means of entry Operator’s microflora Patient’s skin microflora Local infection Migration down catheter inside and out Contaminated on insertion Haematogenous spread Contaminated fluid Susceptible Host • • • • • • • Extremes of age Surgery Extended length of stay in hospital Compromised immune system Chronic disease Antibiotics Vascular access device in-situ Standard Precautions The minimal level of infection control precautions that apply in all situations. PPE Hand Hygiene Clinical waste There are 9 elements to Standard Precautions Patient Care Equipment Linen Isolation Environment Occupational Exposure Spillages Preparation • Clean Work Surface • Hand Decontamination • Reconstitution • Patient Preparationexplanation/skin • Venous access preparation Remember if you are disturbed you need to decontaminate your hands again Administration Additive/solutions Always check: • • • • Packaging Intact Expiry date Particulate Matter Glass for cracks Bolus/flushes Always: • • Clean the port thoroughly Where possible use needle free connector Detection of Infection Infection can present in a number of ways: • Local Site Infection • Microbial Phlebitis • Systemic Infection Inspection At set Intervals, inspect for signs of local infection & phlebitis: 1. 2. 3. 4. 5. Tenderness Erythema Swelling Purulent Discharge Palpable Venous cord Suspected Cannula Infection/ Phlebitis Local• stop infusion, • swab site if discharge visible • if central or arterial line - send tip to microbiology for culture. • Inform medics Systemic• as above, • Vital Signs observations • inform medics. Treatment dependent on individual, presentation, and causative organisms isolated. Phlebitis Scale (Jackson 1998) IV site appears healthy 0 One of the following is evident: •Slight pain near IV site OR •Slight redness near IV site 1 TWO of the following signs are evident: •Pain at IV site •Erythema •Swelling 22 ALL of the following signs are evident: •Pain along path of cannula •Erythema •Induration ALL of the following signs are evident & extensive: •Pain along path of cannula •Erythema & Induration •Palpable Venous Cord ALL of the following signs are evident & extensive: •Pain along path of cannula •Erythema & Induration •Palpable venous cord & Pyrexia No Signs of Phlebitis OBSERVE CANNULA Possibly first signs of Phlebitis OBSERVE CANNULA Early Stage of Phlebitis RESITE CANNULA Medium stage of Phlebitis 3 RESITE CANNULA CONSIDER TREATMENT Advanced stage of phlebitis or the start of thrombophebitis 4 45 RESITE CANNULA CONSIDER TREATMENT Advanced stage of Thrombophebitis INITIATE TREATMENT RESITE CANNULA Giving sets • Change giving set after administration of blood or blood products either every 12 hours or when the transfusion is complete • After 24 hours of TPN administration • After 72 hours if clear fluids are used • All ward prepared infusions should be changed after 24 hours Infusate Sepsis 10 hours after infusion 3 commenced patient spiked a temp. Patient pulled out cannula. Cannula resited same infusion recommenced. Temp spiked again, blood cultures taken. Environmental Pseudomonas sp isolated from blood. Treatment • Stop the infusion - inform medical staff • Send the infusate to microbiology for culture. • Send blood cultures & swab from site. • Monitor vital signs. • Remove the line - send tip to microbiology for culture. Dressings Function of the dressing is: • To protect the site of venous access • To stabilise the catheter in place • Prevent mechanical damage • Keep site clean Documentation • Document all IV sites daily • Nursing Notes • Care Plans • Daily documentation is evidence that assessment has been carried out Key Points • Intravenous drug administration if not done properly can cause infection • Hand hygiene, aseptic technique, correct preparation and administration of iv.drugs/solutions and line changes will minimise the risk of infection • Patients should be closely monitored for signs of infection • Good documentation is essential