Download FINAL EXAMINATION hormone

KING SAUD UNIVERSITY
COLLEGE OF SCIENCE
ZOOLOGY DEPARTMENT
Final Examination – Physiology of Hormones
Second Semester 1428
Time:
2 hours
Student’s name:
Points: 40
______________________________
Student’s number: ______________________________
Group number:
______________________________
Best wishes
Dr. Maha Daghestani
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Q.I
ACTH
Fill in the spaces of the sentences below with the most appropriate
words from the following list:
(5 points)
paracrine
Menstrual flow
Hypothalamus
Genetic code steroids
pituitary-adrenal axis
amines
Nucleotides polypeptide Somatomedins.
Oogenesis
autocrine
Follicular cells
sperm proteins
1. ………………is a gland that controls the pituitary gland.
2. ……………………. are DNA molecules.
3. ……………………… triggers the release of glucocorticoids.
4. ………………is the development of the ova in the ovary.
5…………………….a human cell containing 22 autosomes and a X, Y
chromosomes.
6. ……………………. shed of endometrium from the uterus.
7. ……………………….. is stimulated by stress as part of the general
adaptation syndrome.
8. ……………………… regulators are produced and act within the same
cells of an organ, whereas ………………….. regulators are produced
within one cell and regulate different cell of the same organ.
9. The anabolic effects of growth hormone are produced indirectly via
polypeptide called…………………………..
10. The chemical classes of hormones include………….,…………….,
……………….. and…………………………
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Q.II Place the sign (√) beside the correct answer and (X) beside the
false answer and correct the wrong statements:
(5 points)
1. (√)Calcitonin is an antagonistic hormone to parathyroid hormone.
2. (X) Follicle stimulating hormone (FSH) stimulates T3 and T4 secretions.
3. (X) Hormones are synthesized by exocrine glands.
4. (√) The receptors for protein hormones are present on the outside of the
cell membrane.
5. (√) The effector system monitors whether there is too much, too little, or
just the right content of sodium.
6. (√) Vitamin D is a hormone by classic criteria: made in one place, and
acting in other places.
7. (√) Stress hormones are important to help us meet the demands of stress
occasionally but if they are repeatedly triggered disease will occur.
8. (√) 2000 mg of calcium is the recommended daily intake.
9. (√) PTH production related to plasma calcium levels.
10. (X) LH surge begins 72 hours before ovulation.
11. (√) an immunoassay is a test that uses antibody and antigen complexes
as a means of generating a measurable result.
12. (√) Autocrine and paracrine regulators are local regulators they do not
travel in the blood.
13. (√) The lipophilic hormones bind to nuclear receptor proteins, which
function as liganed-dependant transcription factors.
14. (X) An antigen is the substance that produced as part of the body’s
immune response to protect itself.
15. (√) Absence of Y chromosome and TDF, female develop ovaries
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.
Q.III Circle the letter beside the most correct answer in the following
questions:
(3 points).
1. The hormone that stimulates breakdown of glycogen to glucose in the
liver is:
a. Calcitonin
c.
Thyroxin
b. Insulin
d.
Glucagon
2. The hypothalamus secretes via the posterior pituitary two hormones
these are:
a. Oxytocin and prolactin
b. Oxytocin and ADH.
c. prolactin and growth hormone
d. ADH and prolactin
3. Which of the following hormones uses cAMP as second messenger?
a.
b.
c.
d.
Testosterone
Cortisol
Insulin
Estradiol
4. Thyroid hormone in the blood is bound to:
a. Thyroxine-binding globulin
b. Albumin
c. Thyroxine-binding prealbumin
d. All the above
5. Which of the following is a normal human female?
a. X Y
b. X X Y
c. X X X
d. X X
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6. The flow of information in a cell proceeds
a. from protein to RNA to DNA.
b. from DNA to protein to RNA.
c. from RNA to protein to DNA.
d. from DNA to RNA to protein
7. Thyroid gland:
a.
b.
c.
d.
Secretes a hormone that increases metabolic rate.
Secretes a hormone that reduces blood glucose.
Is located above the kidney.
Secretes steroid hormones.
8. Endocrine system is:
a- a regulatory system, like the nervous system
b- Uses chemical messengers instead of nerve impulses
c- Secret hormones go into blood stream, travel to effector and cause an
effect
d- All the above
9. Which of the following correctly traces the path of sperm from their
site of production to the outside of a man's body?
a. seminiferous tubule–vas deferens–epididymis–urethra
b. epididymis–urethra–seminiferous tubule–vas deferens
c. seminiferous tubule–epididymis–vas deferens–urethra
d. epididymis–seminiferous tubule–vas deferens–urethra
10. A peak in ______ triggers ovulation on about the fourteenth day of
the monthlycycle.
a. progesterone
b. LH
c.
d.
FSH
GnRH
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11. All the following are directly involved in translation in protein
synthesis except:
12.
a. mRNA
c.
t-RNA
b. DNA
d.
Ribosomes
On its way to fertilize a human egg, a sperm cell does not have to
pass through which of the following:
a. Ovary
b. Oviduct
c. Vagina
d. vas deferens
13. An increase in blood volume will cause
a. a decrease in ADH secretion
b. an increase in Na+ excretion in the urine
c. a decrease in rennin secretion.
d. all of the above.
14. Stretch receptors in the aortic arch and carotid sinus
a. stimulate secretion of atrial natriuretic factor.
b. serve as baroreceptors that affect activity of vagus and sympathetic
nerve.
c. serve as osmoreceptors that stimulate the release of ADH.
d. stimulate rennin secretion , thus increase angiotensin II formation
15. which of the following describes the role of inositol triphosphate in
hormone action?
a. It activates adenylate cyclase.
b. It stimulates the release of Ca2+ from the endoplasmic reticulum>
c. It activates protein kinase.
d. It opens Ca2+ channels in the cell membrane.
16. Which of the following terms best describes the interactions of
insulin and glucagon?
a. synergistic
b. permissive
c. antagonistic
d. cooperative.
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17. The immunoassay methodologies are:
a. noncompetitive and competitive immunoassays
b. homogeneous and heterogeneous immunoassays
c. homogeneous and noncompetitive
d. a and b are true.
18. Homeostasis of reproduction depending on physiological levels of the
following hormones:
a. GnH-RH, Gonadotropin stimulating hormones and Sex hormones
b Prolactine, inhibin, activin, follastin and Cytokines
c. Insuline, melatonin Thyroid hormones and leptin.
d. All above.
19. Hormones affect glucose levels
a. Insulin and Glucagon
b. Epinephrine and Norepinephrine
c. Cortisol, Growth hormone and GIP
d. All above.
Q.IV Please answer a & b questions, using short sentence.
A- Mariah had both her left ovary and her right uterine tube removed
surgically at age 17 because of cyst and tumer of these organ. Now, at age
32, she remains healthy and is expecting her second child. How could
Mariah conceive a child with just one ovary and one uterine tube? (1 point)
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B- A young women visited her doctor for premarital gynaecological
examination and requested information on contraception. She plans to have a
large family but “not just yet” She reveals that her faith prevents her from
using any drugs or mechanical means of birth control. What are the only
options of this young woman? (1 point)
Q.V Describe the sequence of events by which hormones maintain the
calcium homeostasis in the body. (6 points)
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Q. VI Define the terms:
(18 points)
1. Permissive action
2. Total body fluids
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3. Homeostasis
4. Resistance Reaction
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5. Cellular Théories of aging.
6. Renin-angiotensin system
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7. Hyporesponsiveness
8. Prevention of osteoporosis
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9. Define the menopause. What does this mean to female?
Q.VII Using a diagram, describe the regulation of hormone secretion
(feedback control).
(2 points)
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Q.VIII As scientist trying to cure osteoporosis, you are elated to discover a
drug that prevent and cure osteoporosis. Describe the mechanism of
action of this drug. Would the drug have negative side effects?
(6 points)
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