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08 - 2012 Emerging Medical Technologies Spotlight: A Report of Investment &
Partnering Opportunities
Description:
This report includes details on 28 emerging medical technology companies that have been identified by LSI's
in-house research team in August 2012.
All companies include technology, market(s), key executive, and contact information.
Coverage includes innovations in a broad spectrum of medical technology areas including:
- Aesthetics/Dermatology Companies
- Biomaterials Companies
- Biotechnology/Cell Therapy Companies
- Cardiovascular Companies
- Dental Companies
- Diagnostics Companies
- Drug Delivery Companies
- Endocrine Companies
- Gastroenterology Companies
- Gynecology/Women's Health Companies
- Imaging Companies
- Neurology Companies
- Oncology Companies
- Ophthalmology Companies
- Orthopedics Companies
- Pain Management Companies
- Patient Management/Monitoring Companies
- Pharmaceutical Companies
- Respiratory Companies
- Spine Companies
- Surgery Companies
- Urology Companies
- Vascular Companies
- Wound Management Companies
Contents:
Brief Technology Descriptions For Companies Covered
- An approach to selectively block serine hydrolases, potentially expanding this class of commercially
validated enzymes as targets in a range of indications such as: central nervous system (CNS) disorders,
cancer, inflammation & metabolic diseases, viral & bacterial infections, and orphan diseases
- The first self-contained disposable blood test to measure the level of proteins (disease biomarkers) from a
single droplet of finger-pricked blood to diagnose, monitor, and manage a variety of medical conditions,
including: heart failure, cancer, osteoporosis, critical pregnancy, and infectious diseases
- 1-Closure device that utilizes a conformable, water-soluble polyethylene glycol (PEG) sealant, which
dissolves within 30 days, leaving nothing behind but a healed femoral artery and 2-A radial compression
band that achieves quick and effective hemostasis, while protecting the ulnar nerve and providing a
comfortable experience for the patient
- Breast cancer screening system with very high sensitivity (95% at 1 cm) that checks for abnormalities using
three proven methods: advanced thermal profiling (ATP), optical spectroscopy, and ultrasound
- Significantly improved accuracy, sensitivity, and convenience in trace and sub-trace analyses using mass
spectrometers and a patented technology platform, to aid in understanding some of the complex underlying
factors that trigger or accelerate many diseases
- Accurate, wearable body monitoring systems for: diabetes management, sleep disorder treatment, weight
loss, and elderly care assistance
- Small molecule caspase activators for the treatment of cancer and other proliferative diseases
- Compounds that leverage the therapeutic potential of Omega-3 fatty acids and other clinically validated
compounds to create new medicines for the treatment of: inflammatory bowel disease (IBD), severe
hypertriglyceridemia & dyslipidemia, multiple sclerosis (MS), chronic kidney disease (CKD), psoriasis, and an
ultra-orphan metabolic disease
- Regional cerebral thermal therapy (RCTT) device to treat insomnia and sleep disorders
- 1-Large and small molecules designed to amplify the body's innate ability to efficiently burn fuels like
glucose and 2-Next-generation highly selective insulin sensitizers
- A therapeutic vaccine with companion diagnostic and monitoring tool, to improve celiac disease
management
- Device for treating chronic obstructive pulmonary disease (COPD), without leaving any implant behind in
the patients' lung tissue
- Portable oxygen concentrator that makes its own oxygen from surrounding air, thus, never running out of
oxygen
- Robots that allow doctors to actually see and respond to patients in ICUs and emergency rooms remotely,
giving physicians the ability to perform routine duties, such as patient rounds, via a web interface
- Next-generation, hand-held, low-powered ultrasound brush that delivers proprietary anti-aging ingredients
to reduce wrinkles
- Small molecule drugs that will provide well-tolerated therapies for cancer, preneoplastic conditions, and
other diseases of pathologic proliferation, including inflammation and viral diseases
- 1-The first heart pacemaker that recruits stem cells to damaged heart tissue and converts them to muscle
and 2-Electrical stimulation device to treat wounds secondary to peripheral limb ischemia, foot ulcers, and
other slow healing wounds
- High-impact therapeutics that address critical unmet needs, primarily in the treatment of
neurodegenerative diseases such as: Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig's disease),
Parkinson's disease, Alzheimer's disease (AD), and multiple sclerosis (MS), as well as lysosomal storage
disorders such as Fabry's disease and Gaucher's disease
- Completely portable systems that provide high-quality computed tomography (CT) images wherever
needed, including: the clinic, Intensive Care Unit (ICU), Operating Room (OR), and Emergency Room
(ER)/Trauma Department
- Compounds to treat pain, epilepsy, and other nervous system disorders such as: anxiety, autism, migraine,
schizophrenia, and bipolar
- An improved and more predictable bioavailability, as compared to currently available Omega-3 products,
for the treatment of lipid disorders (dyslipidemia) and hypertriglyceridemia
- Entirely new class of naturally occurring human supercharged proteins that function inside of cells, to
address a broad spectrum of previously undruggable targets, with potential applications for inflammatory,
infectious, and ophthalmic diseases
- NSAID formulations, which have the potential to reduce the serious and common gastrointestinal (GI) sideeffects caused by virtually all existing NSAIDs
- Small-peptide therapeutics for metabolic diseases such as: obesity, diabetes, and gastrointestinal (GI)
functional disorders like diabetic gastroparesis (DG)
- Simple blood tests to predict the risks of preterm birth, preeclampsia, and other pregnancy complications
- Non-surgical office-based treatments that addresses common bladder disorders such as: stress urinary
incontinence (SUI), overactive bladder (OAB), male voiding dysfunction, and lower urinary tract symptoms
(LUTS)
- The first women's bra that recruits stem cells to breast tissue, for enlargement without surgery. Cells are
recruited via an electrical homing signal from the woman's own fat tissue and bone marrow
- Ready-to-use pharmaceuticals, delivered through patient-friendly injection devices, that will eliminate
reconstitution, simplify administration, and ease the pain of injections
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