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Case Study: Autism Spectrum Disorders – Public Awareness and Physician
Detailing will Drive Market Growth
Description:
This report examines the opportunities and threats within the autism spectrum disorders (ASDs) market.
The analysis is intended to support company strategy and decision-making by providing actionable
recommendations in the current treatment pathway.
To date, only two products have gained approval for the treatment of ASDs; Risperdal (risperidone; Johnson
& Johnson) and Abilify (aripiprazole; Bristol-Myers Squibb/Otsuka Pharmaceuticals) are both approved in the
US for the treatment of irritability associated with autistic disorder.
Scope
- Examination of key recommendations contained in published treatment guidelines for the management of
ASDs.
- Overview of the treatment pathway and identification of three key points of influence that may be targeted
by pharmaceutical companies.
- Discussion of key opportunities and threats facing existing and prospective players in the autism spectrum
disorders market.
Highlights
- ASDs are a complex spectrum of disorders, largely heterogeneous in etiology and symptomatology.
Increasing public awareness of the milder symptoms of the disorders would serve to aid earlier recognition
and presentation. In addition, increasing physician education in relation to the use of validated screening
tools would aid earlier diagnosis.
- Given that only two products are approved in the US for one of the behavioural symptoms of ASDs,
physicians largely rely on off-label prescribing for the majority of symptoms. With few marketing strategies
currently employed, primary care physician detailing has the potential to boost product uptake in the ASDs
market.
- Targeting the core symptoms of ASDs represents a "high-risk, high-reward" strategy given the
heterogeneity of patient presentation and unknown etiologies, yet high population base. Meanwhile, the
traditional route into the ASDs market – targeting of individual symptoms – represents a "low-risk, lowreward" strategy.
Reasons to Purchase
- What do current treatment guidelines recommend in relation to pharmacological treatment of ASDs?
- What is the current typical treatment pathway for patients with ASDs? Where are the key points of
influence for market players?
- Which segment of the ASDs population offers the greatest commercial potential to developers?
- What actions can pharmaceutical companies take in order to maximize the uptake of products indicated
for the treatment of ASDs?
- Which factors pose the greatest threat to the commercial potential of products indicated for the treatment
of ASDs?
Contents:
OVERVIEW
- Catalyst
- Summary
EXECUTIVE SUMMARY
- Update details: April 2012
- Strategic scoping and focus
- Datamonitor key findings
- Related reports
CASE STUDY IN AUTISM SPECTRUM DISORDERS
- Introduction
- Treatment guidelines for autism spectrum disorders
- - Treatment should be individualized and systematically monitored
- - Pharmacological treatment is considered an adjunct to behavioral and psychological intervention
- - Published treatment guidelines are based on mixed clinical trial data and focus on pediatric patients
- Treatment pathway
- - First point of influence: increase public awareness in order to drive up patient presentation
- - Second point of influence: improved primary care physician education will aid earlier diagnosis and
intervention
- - Third point of influence: physician detailing will boost product potential
- Opportunities and threats
- - Despite increasing competition, growing industry interest will be beneficial for new market entrants
- - Key opportunities
- - Key threats
BIBLIOGRAPHY
- Journal papers
- Websites
- Datamonitor reports
APPENDIX
- Contributing experts
- Conferences attended
- Report methodology
TABLES
Table: Treatment recommendations for behavioral symptoms of autism spectrum disorders from a selection
of guidelines, 2012
Table: Summary of key opportunities and threats within the autism spectrum disorders market, 2011
FIGURES
Figure: Autism spectrum disorder patient care pathway in the seven major markets, 2012
Figure: Comparison of incentives conferred by orphan product policies across the US, EU, and Japan, 2012
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