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Chapter 11 Diet and Health Chapter 11 Diet and Health Heart Disease Atherosclerosis Hypertension Hypercholesterolemia Health Risk Factors Associated with Heart Disease Primary Controllable Risk Factors Cigarette smoking affects 25% of adults Hypertension affects 25% of adults Hypercholesterolemia affects 20% of adults Physical inactivity affects 75% of adults Obesity affects 33% of adults Diabetes affects 10% of adults Non-controllable risk factors Genetics Male Age Contributing risk factor stress Atherosclerosis “scleros = “hard; “osis” = too much 1 type of hardening of arteries caused by build up of plaque o plaque consists of cholesterol (oxidized LDL), calcium, white blood cells, etc. 85% of all heart disease has atherosclerosis as underlying cause Hypertension Blood pressure is pressure exerted by blood against walls of blood vessels concern is in arteries high blood pressure known as “Silent killer” 120/80 normal systolic vs diastolic 140/90 high B.P. B.P. tends to rise with age don’t except this 1 in 4 U.S. Americans 1/3 not aware of it contributes to 700,000 deaths each yr. Hypercholesterolemia Functions of cholesterol hypercholesterolemia - elevated blood cholesterol oxidized LDL’s main concern Values (total cholesterol) *desirable < 200mg/dl 1 in 5 people; with age Primary risk factor for CHD So What do I do Nutritionally to Risk of These Diseases? Prevent & Treatment of HBP Weight loss (if overweight, most important factor) or maintain appropriate weight o apply diet for weight loss Reduce Na+ intake <2400 mg/day (some sensitive to Na+) read food labels (watch canned & processed foods) salt during cooking (use herbs & spices) limit foods with visible salt (chips, pretzels, nuts, etc) avoid putting salt on food Choose fresh fruits & vegetables (low Na+ & good K+) Adequate magnesium o most people are sub clinically def. whole grains & legumes Limit alcohol consumption Non-diet related factors o Stop smoking o Stress management o Aerobic exercise attacks problem, medications attack symptoms What Can I Do to Total Cholesterol & LDL? Maintain ideal body wt. or body weight if overweight saturated fat & “trans-fatty acids” o <10% of total calories substitute monounsaturated fats (olive oil) for saturated dietary cholesterol? o <300mg/day complex carbs & fibers anti-oxidants oxidized LDL’s seem to be problem vit. E, C, Beta-carotene, selenium (phytochemicals) To HDL’s Weight reduction & leanness most important factor IF overweight Moderate alcohol consumption? Aerobic exercise, >90 minutes/wk Smoking cessation Additional Nutritional Information to Reduce Risk of Heart Disease Follow guidelines -55% carb (2/3 complex) -<30% fat (**sat. fat) -15% protein -20-30 g of fiber -*minimize eating away from home -decrease sugar intake Antioxidants: plant foods; insufficient evidence to support supplements (look for color) B Vitamins: normal metabolism of homocysteine requires adequate supply of folate & other B vitamins high homocysteine levels have been related to risk for heart disease in most but not all studies Soy Protein: consumption of soy protein in place of animal protein tends to lower blood levels of cholesterol, LDL’s, & triglycerides without affecting HDL Omega-3 Fatty Acid: consumption of one fatty fish meal per day may have beneficial affect on heart disease Nutrition & Diabetes Mellitus “There is a strong link b/t Type 2 diabetes & sedentary living. Greatest benefits occur in those who incorporate regular physical activity into their lives” What is Diabetes Mellitus? Metabolic disease characterized by high blood glucose Diabetes Type I 5-10%, damaged pancreas “autoimmune disease” Prone to ketoacidosis (life-threatening) -Usually starts in children, tend to be slim -Need insulin injections Type II 90-95%, - “insulin resistance syndrome” Develops gradually used to be 45yrs, obese, sedentary, & family history Now seeing in younger pop. Most do not need insulin “syndrome X” – obesity, HBP, high insulin levels, & dislipidemia Complications of Diabetes $100 billion/yr in health care costs, 10th? leading cause of death Heart disease death rates 2-4x’s > non-diabetics Risk of stroke is 2-4x’s > non-diabetics High blood pressure – 60-65% of diabetics Blindness – leading cause of new blindness 20-74yrs of age Diabetic retinopathy Kidney disease – leading cause of end renal stage Nervous system disease – 60-70% (impaired sensation) Amputations - >1/2 of lower limb amputations are diabetics Pregnancy – 3-5% result in newborn deaths vs 1.5% in non-diabetics Depression/anxiety are common due to emotional & social impact of diabetes & treatment risk for developing dementia such as Alzheimer’s Type 2 Diabetes & Body Weight Gaining just 10 lbs risk of developing diabetes (2) 25% More frequent when weight is around abdomen (android) Weight loss improves insulin resistance & glucose levels Risk reduction for developing Type 2 diabetes who maintain ideal weight is 50-75% compared to obese (most important prevention measure for Type 2 diabetes is to be active & maintain ideal body weight) Nutrition for Diabetics Similar general guidelines need to follow guidelines for heart disease minimize high glycemic foods Carbs. 50-55% watch simple sugars Fiber intake 25-30 g/day Planning meals regular, exercise, meds. Create caloric deficit if overweight Exercise Benefits for Diabetics **Improved insulin sensitivity During exercise or activity, insulin is NOT needed to move sugar (glucose) into body cells caloric expenditure (weight control) Reduce risk for other health issues Improved blood lipids blood pressure in hypertensives risk of cardiovascular disease Enhanced quality of life, improved self esteem *will not fix problem for Type 1, may in Type 2 Nutrition and Cancer Cancer 1 in 4 in U.S. will contract cancer 20-50% attributable to diet Suggested in colon, prostate, pancreas, & breast cancer by 50% if all adopted healthy diet excessive fat, alcohol, & calories, and low fruit & vegetables are associated with cancer foods can be cancer causing?, cancer promoting, or protective Development of Cancer exposure to carcinogen entry of carcinogen into cell initiation of cancer, possibly altering genetic material acceleration by promoters metastasis (spreading) Nutrition and Cancer What Can We Do? Increase intake of green, red, orange & yellow fruits & vegetables probably most important due to phytochemicals and anti-oxidants; high red meat intake related to colon cancer?? may be other related factors (high cals, high sat. fat, low fiber) High fiber diets may be protective due to excretion of bile & absorbing toxins may relate to fruit & vegetables Vitamin E, C, folate, & beta carotene (ANTIOXIDANTS) in diet may be protective (phytochemicals) Crucifers Broccoli, Kale, Brussels Sprouts, Cabbage, Couliflower Contains several phytochemicals including Indols Eating 3-4 servings of broccoli or other crucifers per week may have a positive effect on cancer risk reduction. A serving equals approximately 1/2 cup of broccoli. Nutrition and Cancer Smoke from wood or charcoal settles on food To minimize effect: Line grill with foil Don’t burn food Trim off fat or remove skin