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The University of Chicago Department of Statistics Master’s Seminar QINGLING DU Department of Statistics The University of Chicago Fitting Regression Models Under Case-control Sampling Wednesday, July 26, 2006 at 9:30 AM 110 Eckhart Hall, 5734 S. University Avenue ABSTRACT Data arising from case-control sampling are the result of complex design involving stratification of the response. Some methods are developed to fit the regression models under case-control sampling for longitudinal data or for secondary analysis. For some models such as Logistic and Poisson models, valid point estimators and asymptotic variance of the oddsratio parameters are obtained by modifying the prospective logistic regression model to cater for this sampling scheme. The profile likelihood technique for binary response and usual survey weight method with weights inversely proportional to the selection probability are also presented. The modified prospective method and weight method are applied on the analysis of a simulated data set and an actual data set. Information about building access for persons with disabilities may be obtained in advance by calling the department office at (773) 702-8333.