Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Epilepsy Seizure Detection Algorithms Farnaz Nassirinia DSP, 2015 1/10 The Nervous System ● Interconnected network of neurons ● Neurons: primary structural units of nervous system ● Ubiquitous in the body(10^11 neurons) ● Chemically and electrically transmitting signals ● Sensory Input >> Integration >> Motor output 2/10 Electrocorticography (ECoG) ECoG recording setup at Erasmus MC 3/10 Multi-channel ECoG 4/10 Multi-channel ECoG Essential for a healthy functioning brain: neurons fire asynchronously 4/10 Epilepsy ● Neural disorder ● Normally neurons fire asynchronously ● Neurons fire highly synchronous in epilepsy: seizure ● Symptoms: ○ Unconsciousness ○ Jerky movement ○ Neurotrauma ● Many types of seizures. Focus of this project: ■ Absence seizure ■ Grand mal seizure 5/10 Absence & Grand Mal Seizures Absence seizures Tonic-clonic seizures 6/10 Synchronization 7/10 Synchronization 7/10 Synchronization 7/10 Synchronization 7/10 Synchronization Synchronicity is the key! 7/10 Wavelet filter Closed-loop circuit for detection and suppression of epileptic seizures being used at Erasmus MC Taken from M. Van Dongen, 2014 8/10 Problem Develop an algorithm to detect : - Absence seizures within 300 ms. - Grand-mal seizures within 5 seconds of the tonic phase Data provided by Erasmus MC Neuroscience department: (Recordings from mice) - 24 hours of ECoG with absence seizures - 24 hours of ECoG with Grand-mal seizures 9/10 Absence & Grand Mal Seizures Absence seizures Tonic-clonic seizures 10/10