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“Special K Project” TCNP Meetings September 2012 – June 2013 The meetings will take place on the 2nd Tuesday of each month, from 11:00 a.m. to 12:30 p.m. in the Darner Room (Ross G007). Thursday, September 6, 2012, 4:00 pm Memorial Service for Yu-yi Lin Tuesday, September 11, 2012 No Meeting Tuesday, October 9, 2012 Taverna Lab: Romeo Papazyan: “Identification of histone post-translational modification states in heterochromatin” & Tonya Gilbert: “Mechanistic insights into HAT complex localization and function in gene expression” Tuesday, November 13, 2012 Boeke Lab: Zheng Kuang: “A high-resolution view of histone modifications and transcription across distinct metabolic states in budding yeast” & Anna Sliva: “FACS-based genetic screens in S. cerevisiae to identify genes & histone residues involved in dynamic processes” Tuesday, December 11, 2012 Cancelled Tuesday, January 8, 2013 Espenshade Lab: Zongtian Tong, PhD: “A proteomic approach to identify substrates for the Golgi E3 ubiquitin ligase Tul1” & Sara Clasen: “A function for the oxygen-sensing prolyl hydroxylase Ofd1 in translation” Tuesday, February 12, 2013 (Lincoln’s Birthday) Cotter Lab: Elisabeth Hersman & Isabel Martinez Ferrando: “Analyzing Histone Modifications of Calorie Restricted Yeast with Mass Spectrometry and Chemical Derivatization” Tuesday, March 12, 2013 Zhu & Matunis Labs: Shaohui Hu, PhD: “DNA Methylation Presents Distinct Binding Sites for Human Transcription Factors” Kate Guzzo, PhD: “SUMO Match.com: Helping SUMO Find Its Partners” Tuesday, April 9, 2013 Michaelis Lab: Cancelled Tuesday, May 14, 2013 Guest Speakers: Scott Holmes (Wesleyan University, Dept of Molecular Biology & Biochemistry) “Moonlighting enzymes: a metabolic protein regulates gene silencing in yeast” Marc M. Greenberg (Johns Hopkins University, Dept. of Chemistry): “Histone Catalyzed Reactivity of Damaged DNA in Nucleosome Core Particles” Tuesday, June 11, 2013 Guest Speakers: Zhibin Wang (JHBSPH, Dept. of Environmental Health Sciences): “DNA methylation patterns in genome integrity, genomic imprinting, gene transcription and splicing” Anthony Leung (JHBSPH, Dept. of Biochemistry & Molecular Biology): “Poly(ADP-ribose) regulation on microRNA activities and beyond”