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Aplikasi dendrimer sebagai sistem penghantar obat-obatan Aplikasi dendrimer sebagai sistem penghantar obat-obatan Dendrimer application as drug delivery system JURNAL KEDOKTERAN YARSI 12 (2) : 096-106 (2004) by Yuhernita Department of Chemistry, YARSI UNIVERSITY School of Medicdine Jakarta ABSTRACT Many studies in design, synthesis and polymer properties have been conducted to discover a new polymer that can be used as a drug delivery agent. Due to the improvement of drug targeting and therapeutic efficacy, various polymer carriers have been evaluated. However, the inability of drug or steric constrains of polymeric systems to reach the target site decreased drug activity. Dendritic polymers are considered alternative for the preparation of monodisperse drug carriers due to their well-defined structure, multivalency, and flexibility of functionalization. These unique properties have made their application in pharmaceutics and chemistry particularly attractive. This review elaborates the preparation of dendrimer and their potency for many applications, especially in drug delivery system. 1/1