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* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
IMPORTANT POINTS:: U need to memorize some of the important values..like: Serum ca,k,cl,na,hco3,phosphorus,magnesium..anion gap,ph. ABGs(arterial blood gases):Po2,Pco2,O2 saturation. Gh,serum osmolarity,urine osmolarity. BUN,Uric acid,creatinine,albumin,bilirubin(direct,idirect). Protein in urine. Alt,Ast,amylase.cholestrol,glucose. Esr,pt,apt,fibrinogen,platelet count. Mch,mchc,mcv. Hb,retic count,hct and erythrocyte count. CSF R/E ……………………………………. Important topics: -Opening in diaphragm. -Respiratory capacities. -celiac truk and branches -type of hyaline cartilage -cns recepters -epithelium -pharyngeal pouches,clefts -epithelium derivatives -skull foramina -cytochrome inducers and inhibitors. -heart blood supply -page 600 azim shaikh -dna and rna viruses -bones of hand -purines and pyrimidines -ulcerative colitis and crohn’s -tumor markers -type of errors—biostat -reflexes values -age related type of meningitis -cardiac enzymes -carotid sheath content -chemorecepter and baroreceptor -hormones second messengers -T and B cells’ CD numbers -Amino acids derivatives -Glycogen storage diseases -joint classifications. -cartilage types(hyaline,fibrocartilage,elastic ---examples) -bones classifications -thirst is stimulated by: 1. increased ECF osmolarity. 2. decreaded volume of ECF. 3. Angiotensin III -Median nerve: >Descends on Lateral side of axillary and brachial arteries. >Enters palm Behind the flexor retinaculum. >supplies most of the flexors of the forearm(arm flexors supplied by musculocutaneous nerve) >supracondylar fracture cause median nerve injury---------apelike hand deformity -Ulnar nerve: >Descends on Medial side of axillary artery and brachial artery. >passes behind Medial epicondyle of humerous. > enters palm anterior to the flexor retinaculum. >injury leads to claw deformity. Radial nerve: -Descends Infront of lateral epicondyle. -supplies extensors of arm and forearm. -lesion causes wrisr drop. Axillary nerve: -passes through Quadrangular space. -lies against surgical neck of humerus. -lesion wil cause paralyzed deltoid and loss of cutaneous sensation over lower 1/3 of deltoid region. -chlorpromazine can cause parkinsonism -parkinsonism is aggrevated by Haloperidol -Digoxin toxicity can increase by chlorothiazide -centraly acting antihypertensive is methyldopa -Serotonin is secreted from carcinoid tumor which is responsible for sign and symptoms. FOOT everters and inverters: Inverters: -tibialis anterior -tibialis posterior Everters: -peroneus longus,brevis and tertius -Granulation tissue in MI appears within 9-10 days and becomes prominent within 2-3 weeks. Conducting system blood supply: -SA node__RCA(sometimes LCA,but mainly RCA) -AV node__RCA -AV bundle__RCA -RBB__LCA -LBB__RCA+LCA ECG diagnosis of MI: A.Anterior wall(LAD):v1-v4 1.anteroseptal__LAD (v1-v2) 2.anteriolateral__LAD or LCX(v4-v6) B.Lateral wall(LCX)__I,aVL C.Inferior wall(RCA)__II,III,aVF -posterior interventricular artery accompanies middle cardiac vein -Anterior interventricular artery is accompanied by great cardiac vein. _heparin____monitor aptt _warfarin___monitor pt -on contraction of diaphragm the intrathoracic pressure decreases. _Lateral horn is present in T1-L2 _Dorsal colums present only above T5 _Large ventral horn is present in (C5-T1+L2-S2) -Eosinophilia present in: hodgkin lymphoma and polyarteritis nodosa. -PGI2__by endothelial cells -TXA2__by platelets Blood transfusion induced electrolye embalance is as follows: -hypocalcemia -hyperkalemia -hypothermia -metabolic acidosis -left shift of oxy-hem curve *common peroneal nerve injury__loss of everion and dorsiflexion *Tibial nerve injury__loss of inversion and planteflexion. -pelvic parietal peritoneum is supplied mainly by Obturater nerve. Lymph drainage: *labia majora and glans penis---superior inguinal L.N *cervix—internal and external iliac L.N *prostate__internal iliac L.N *Urinary bladder__internal and external iliac L.N -allantois__Urachus__median umblical ligament -Somatotropic (acidophilic) adenoma__gigantisim -corticotropic (basophilic) adenoma__cushing disease -prolactinoma---acidophil(30%) -GH adenoma—acidophil -ACTH adenoma---basophil -TSH adenoma—basophil(chromophobe) *in axila—cords of brachial plexus *base of neck----roots *posterior triangle of neck---trunk and division *detoxification of drugs---ESR -Boat shaped cyst—pneumocystis carnii -Epidural __middle meningeal artery -Subdural__superior cerebral vein TYPHOID fever investigations: -1st week____blood culture -2nd week___antibody/widal -3rd week___stool -4th week___urine culture -vit b12 absorbed from terminal ileum -middle rectal artery remains in true pelvis -renal medullary rays—collecting ducts -Anxiolytic effect by GABA -lipid which does not contain glycerol is sphingomyelin -taste fibers from anterior 2/3 tongue passes thru internal capsule -for controlling tachycardia;; Amiodarone>lidocaine>procainamide -glucose transported mainly by facilitated diffusion -amino acids—Na cotransport -sarcoma—hematogenous -carcinoma—thru lympatic -night terrors happens in NON-REM -nightmares happens in REM -glutamate for fast pain fibers -substance p for slow fibres -glutamate released by rods and cons -blood brain barriers made by astrocytes -fungiform—salty and sweet -foliate---sour taste -circumvillate—bitter taste Stretch reflex: -monosynaptic -Ia fibers affected - alpha motorneurons Inverse muscle stretch reflex: -Disynaptic -Ib fibres -gamma motorneurons -Golgi tendon organs -Horner’s syndrome happens if lesion above T1 -in the cerebellum..granule cells is the only excitatory neurons while all others are inhibitory -trouble going downstairs==Trochlearnerve damage -trigeminal neuralgia—v2+v3 -Glossopharyngeal nerve supplies carotid body and parotid gland -loss of accommodation causd by damage to midbrain -lesion to pretectum leads to loss of reaction to liht but intact accommodation -liquid dysphagia is due to neuromuscular incordination -study brain stem lesions very well..for example medial medullary syndrome..etc -nuclei which lies beneath the fourth ventricular floor: Vestibular,vagal,abducent,hypoglossal. -spinal cord ends: *in infants:L3 *in adults:lower border of L1 -Subarachinoid space ends at (S2-S3) -internal capsule---projection fibres -at the level of superior colliculus— occulomotor nerve nucleus-midbrain— red nucleus -genu+anterior 2/3 of posterior limb----------------motor -increased plasma osmolarity stimulates osmorecepters in anterior hypothalamaus. -intestinal cells of kajal are the pacemakers of GI smooth muscles. -vommiting and swallowing centres is in the medulla -most colonic water absorption occur in proximal colon -in multiple myeloma,the alkaline phosphatase is not increases. -tight junction in colon -leaky junction in small intestine and gall bladder -cryptsecretion -villiabsorption -ABO incompatability in infants: *O motherA orB baby *A motherB or AB baby *B motherA or AB baby -progesteron is reason behind increased temperature during ovulation -Fibroadenomanot precursor of CAbelow 25 yr -Fibrocystic changesprecursor fro CA20-50 yr -Granulosa cell tumorcall exner bodies -Dysgerminomashriler duval bodies --in renal failure: *early stage—dilute urine *late stage____concentrate urine -fat absorption occur primarily in jejunum -oblique fissure extends from T3—6th costal cartilage on both lungs -groove for subclavian artery is at first rib. -azygos vein enters thorax inlet -right middle lobe has 2 bronchopulmonary segment -diaghragm is not attached to T 10 -Tendon of popletial muscle is intracapsular -DIFFICULTY in: *flexing knee and thighsartorius *flexing knee and extending hipsemitendinous *flexing hip and extending kneerectus femoris -Conus medullaris is pial extension to the coccyx -revise muscles of laryns..narroeing,widening,tensing vocal cord…etc -absorption of short chain FFA happens in colon -osteosarcoma in metaphysis -occulocardiac reflex mediated by trigeminal -thyroid derived from endoderm -albumin has low molecular weight and high concentration -amoebic abcess occur in Cecum>ascending colon>sigmoid >rectum -somites are present in paraxial mesoderm -strongest layer in small bowel in circular layer -embryonic primary vesicle is mesencephalon Lymph drainage of -lateral handinfraclavicular -medial handepitrochlear -lateral ventricle roof formed by body of corpus callosum -dermatome of perineal region is S3S4 -CVAheart sounds in JVP C wave first sound V wave 2nd A wave 4th -in cell cycle: Replicationinterphase Divideprohase Align 2 chromosomesmetaphase -noradrenaline and serotonin metabolized by MAO -adrenaline by COMT -liver makesfactors 1,2,7,9,10 but not 4(calcium) -connections of cerebulum *cerebellum to midbrain through superior cerebellar peduncle<SCP> *cerebellum to pons through MCP<middle> *cerebellum to medulla through ICP<inferior> -narcolepsydefect in hypothalamus -U wave in papillary repplarization Pt had ankle sprain: -if pt can stand on toerupture of plantaris tendon -if cannot stand on toerupture of achiles tendon At the end: Study plan totally depends on how much you can study in one day,study with concentration and make your basics clear first..text books along with first aid and mcqs books are must..u cannot leave any of that..for mcqs books I highly recommend asim and shoaib,chandkians and rabia ali,although its very heavy book and makes person depressed by how difficult its mcqs although its very much important..search for all the past papers of fcps1.atleast last 3 years and solve them..they can come handy.. U need to have refreshment daily..its not good to only study study study..give ur brain a break every once and while..motivate yourself for studyng..like if I finish this chapter I wil go do something I like and so on..but not too much break.. I advice to look at notes in beginning of your study process and at the end as revesion..as it hav helped me a lot at the end. If it contains some mistakes then forgive me..i hope it can help u all.. At the end I wish all of you best of luck and I hope you all clear this exam.. Regard: DR.Zainab..