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Special Psychiatric Emergency Presentations Nicholas Cascone, PA-C Emergencies related to psych medications Antipsychotics side effects Akathisia responds to β-blocker therapy such as propranolol Dystonia (torticollis, oculogyric crises, etc.) respond to anticholinergics (e.g. benztropine, diphenhydramine) Parkinsonism requires dose reduction and anticholinergic therapy as above Neuroleptic malignant syndrome: emergency presentation with rigidity, fever, tachycardia, BP lability, and altered mental status – discontinue antipsychotic and give dantrolene or bromocriptine, hydration, supportive treatment in intensive care setting Emergencies related to psych medications Benzodiazepines Used frequently in the ED for anxiolysis or sedation Anxiolytics: alprazolam (Xanax®), lorazepam (Ativan®), clonazepam (Klonopin®) Longer-acting anxiolytics/mild sedatives: diazepam (Valium®), chlordiazepoxide (Librium®) Sedative-hypnotics: temazepam (Restoril®), triazolam (Halcion®), flurazepam (Dalmane®) Overdose is treated with flumazenil Paradoxical response requires discontinuation Anorexia nervosa Dx by usual signs and symptoms BMI 16, < 85% of expected weight for height Unexplained primary amenorrhea Derangement of body image ED treatment: Volume repletion Correction of electrolytes Aggressive refeeding leads to hypertonic dehydration, hypernatremia, pancreatitis Anorexia nervosa Criteria for hospitalization: Weight loss of 30% or more in 3 months Severe metabolic disturbance Suicidality Failure to maintain outpatient weight contract Family crisis or denial Severe bingeing and purging Need to initiate therapy (psychotherapy, family therapy, pharmacotherapy) Panic attack Symptoms Palpitations/tachycardia Chest pain/pressure SOB/smothering Diaphoresis Tremor Choking sensation/globus Nausea/abdominal complaints Dizziness/lightheadedness/syncope Paresthesia Chills/hot flashes Fear of: going crazy, loss of control, dying, syncope Derealization/depersonalization Panic attack – medical differential Cardiovascular: angina, MI, MVP, PACs Pulmonary: angina, PE, hyperventilation Endocrine: hyperthyroid, hypoglycemia, pheochromocytoma, Cushing’s Neurological: stroke/TIA, partial seizure, migraine, Ménière’s Drugs/medications: caffeine, cocaine, thyroid meds, SSRIs, cannabis, steroids, β-agonists, triptans, nicotine, hallucinogens, anticholinergics Withdrawal syndromes: alcohol, barbiturates, benzodiazepines, opiates Panic attack – treatment In ED: benzodiazepines Referrals Psychotherapy – cognitive-behavioral Psychiatry SSRI Buspirone Short-term “bridging” benzodiazepines Emergencies involving alcohol Trauma – assault, MVA, other injuries 25% of assaults involve alcohol 45% of fatal MVAs involve alcohol Head trauma often overlooked when presenting with alcohol intoxication Obtain CT of head when: History of head injury No improvement in 3 hours Worsening of mental status while under observation Emergencies involving alcohol Withdrawal Four steps of alcohol withdrawal 6 – 8 hours since last drink: autonomic hyperactivity – tachycardia, diaphoresis, tremor 24 hours since last drink: tactile and visual hallucinations 24 – 48 hours since last drink: motor seizures 3 – 5 days since last drink: delerium tremens – altered mental status, convulsive seizures, 5 – 15% mortality Emergencies involving alcohol Treatment of alcohol withdrawal Fluid resuscitation with D5NS or D5LR and thiamine (100 mg/L) Patient placed in a quiet area with minimal stimulation Lorazepam 2 – 4 mg IV q 15-30 minutes until light sedation is achieved MgSO4: 4 g IV in 1 – 2 hours For pts with seizures: CT indicated if head trauma, focal seizure, persistent postictal defect in consciousness Emergencies involving alcohol Criteria for admission Medical complications such as CHF, infection More than 8 mg of lorazepam needed Referral for treatment of alcoholism Tests for conversion disorder/ malingering Sensation Yes/no test: pt closes eyes and responds yes/no to touch stimulus – “no” response favors conversion Bowlus & Currier test: pt extends crossed arms, thumbs down, palms touching, interlocking fingers, arms then rotated towards chest False response to sensory stimulus difficult d/t distortion of position “Strength” test: pt closes eyes and moves touched finger to assess “strength”. True sensory loss would not allow pt to determine which finger is being tested Tests for conversion disorder/ malingering Pain Gray test of abdominal pain With psychological pain, pt closes eyes during palpation With organic pain, pt watches palpation so they can guard tender Motor areas Drop test: “paralyzed” extremity dropped from above the face will miss it Thigh adductor test: examiner places hands against inner thighs of patient. Pt is told to adduct normal leg against resistance. In pseudoparalysis, other leg will also adduct Hoover test: examiner cups both heels of patient. Pt is told to elevate normal leg. In pseudoparalysis, other leg will push downward. Pt is told to elevate weak leg. Absence of downward pressure indicates noncompliance. Tests for conversion disorder/ malingering Coma Corneal reflexes retained in awake patient Seizure Resistance to covering of mouth & nose indicates pseudoseizure Palpation of abdominal muscles reveals lack of contraction in pseudoseizure Blindness Opticokinesis: tape with alternating black and white sections pulled laterally in front of patient’s open eyes induces nystagmus in patient with intact vision