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CHM 708
Central Nervous System
Neurons
Synapse
Neurotransmitters
Acetylcholine
 Monoamines

◦ Epinephrine (adrenaline), nor-epinephrine, dopamine,
serotonin (5-hydroxytryptamine), histamine

Amino-acids
◦ Glutamate, g-aminobutyric acid (GABA), glycine,
aspartate, D-serine

Peptides
◦ Somatostatin, substance P, opioid peptides, etc.

Small molecules
◦ NO, CO
Synthesis of amobarbital
Barbiturates
Benzodiazepines
More benzodiazepines
Still more benzodiazepines
Synthesis of diazepam
Beta blockers
Used to treat

Hypertension

Angina pectoris

Cardiac arrhythmia

Migraine

Tremor

Glaucoma (used topically)
Examples of beta blockers
More beta blockers