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Consult Dilemma: a case of divergent opinions Alev Wilk Primary Care Conference 4/18/07 Conflict of Interests None Objectives Patient case Teaching points in septic arthritis Teaching points in consult management Patient Case 47 y.o. obese man with IDDM who was admitted with a one week history of progressive right shoulder pain & diffuse myalgias No recent trauma, pulmonary, CV, GI, GU problems. He denied F/C/S, HA, chest pain, sob, n/v. Medications included insulin 70/30 20Units bid and prn vicodin Patient Case He worked as a welder; nonsmoker; light drinker; no IV drug use; monogamous Exam findings: Tenderness & swelling in the right shoulder & knee, systolic heart murmur, 1st toe abrasion. Labs: Leukocytosis, elevated esr/crp. TEE negative; HIV negative; A1C is 7.2. Patient Case First 24 hours: – Rheumatology consult: diagnostic and therapeutic taps; continue joint surveillance – Blood & joint fluid cultures grew gram positive cocci in clusters – ID consult: antibiotic management – Orthopedic consult: arthroscopic irrigation and debridement of the right shoulder. Patient Case One week – He improves on IV antibiotics but continues with debilitating right shoulder pain and right knee pain. – Rheumatology: deferred the shoulder to ortho but continued serial right knee taps. – Orthopedics: no further intervention or imaging. Tell Rheum to stop tapping the knee. Septic arthritis Medical exam – Very tender though less swollen shoulder and knee (extension to adjacent tissues) – Afebrile, normal WBC but esr is high. Medical management* – Antimicrobial combination therapy – Increase bactericidal activity and prevent development of resistance – Continue IV nafcillin and rifampin *N Engl J Med 1998;339:520-532 Septic Arthritis Staphylococcus aureus infections* – Produces proteolytic enzymes that destroy tissue & facilitate spread of infection – Metastatic infection: spread to bones, joints, kidney and lung which become potential foci for recurrent infections – Clinical experience: extension from extra- to intra-articular regions and osteomyelitis** *N Engl J Med 1998;339:520-532 **J Bone Joint Surg Am 2006; 88(8): 1802-6 Septic Arthritis Risk factors*: – Age > 80 – Diabetes: 10-20% of patients are colonized with S.Aureus (highest in diabetics) – RA – Prosthesis – Recent joint surgery – Skin infection – HIV infection *JAMA, April 4, 2007; 297(13); 1478 Septic Arthritis Repeat imaging revealed enlarging fluid collections in the shoulder, thigh as well as A-C osteomyelitis Orthopedic intervention with surgical drainage, acromioplasty. Reconsulted ID, same antibiotics with a time extension Septic Arthritis: take-home points Staph aureus can present as a metastatic infection that is progressive & persistent Risk factors are numerous in adults Joint surveillance with exam & imaging Consult Dilemma: take-home points We direct the consultants, they do not direct us We are specialists with the wide-angle lens and the telephoto lens We are specialists in managing behavioral and physical medicine