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Never Too Old: Substance Use Problems and Older Adults The University of Texas at Austin June 2009 Acknowledgements Development of this presentation was made possible through a Gero Innovations Grant from the CSWE Gero-Ed Center’s Master’s Advanced Curriculum (MAC) Project and the John A. Hartford Foundation. Never Too Old: Substance Use Problems and Older Adults* Incidence and Prevalence Risk Factors Prescription Drugs Screening Diagnosis Dementia, Delirium, and Psychiatric Comorbidity Culture Intervention References * Disclaimer: This presentation does not constitute legal, medical, or psychiatric advice. How Many Older Adults Are Affected by Alcohol and Drug Problems? 15% of men and 12% of women aged 60+ seen in primary care settings drank more than NIAAA recommended limits (Adams, Barry, & Fleming, 1996) As many as 17% misuse alcohol or prescription drugs (in addition to tobacco, these are the major problems) (Blow, 1998) Drug Use Among Adults Aged 50 and Older Between 1999-2001: 1.6 million adults reported some illicit drug use 719,ooo adults reported marijuana use 911,ooo adults reported using prescription psychotherapeutics for non-medical purposes It is projected that by 2020: 3.5 million adults will report illicit drug use (113% inc.) 3.3 million adults will report marijuana use (355% inc.) 2.7 million adults will report use of prescription psychotherapeutics for non-medical purposes (193% inc.) (Colliver, Compton, Gfroerer, & Condon, 2006) Ethnic Population Comparison (Office of Applied Studies, 2005) As the Life Cycle Turns: Substance Abuse Risks Across Stages • Youth: genetic predisposition, temperament, nonconformist/antisocial behavior (delinquency/aggression), adults’ example, high-risk living environment, peer pressure, media, gender, ethnicity • Young Adult: intimate relationships, sex, college, early family stressors • Middle Age: achieving life goals, later family stressors • Older Adult: empty nest, loneliness/lack of social support, changing roles, losses, health problems, metabolism, prescription drug use (See, for example, National Institute on Alcohol Abuse and Alcoholism, 2000) Important Considerations Drinking and illicit drug use decline with age, but problems can occur at lower doses. Younger age cohorts more likely to drink and become dependent than older cohorts, but problems will increase as baby boomers age. Gender gap has decreased but men still have more alcohol problems; women, however, more likely to begin heavy drinking later in life. Older people are largest users of Rx drugs, and women prescribed more psychoactive Rx drugs than men. Most older adults do not intend to abuse Rx drugs (less nontherapeutic use than younger people). (Blow, 1998; Center for Substance Abuse Prevention, 2002; National Institute on Alcohol Abuse and Alcoholism, 2000) Alcohol Metabolism and Aging Tolerance to alcohol decreases because: Lean body mass decreases (as body water decreases, alcohol concentration increases) Gastric alcohol dehydrogenase decreases (slows alcohol pharmacokinetics, increases alcohol that enters bloodstream) Increased alcohol sensitivity/decreased tolerance (Blow, 1998; Fingerhood, 2000) Misuse/abuse of prescription drugs has declined because: Safer drugs with fewer side effects Stricter federal and state regulations Health care providers given best practice guidelines Physicians better educated to treat older patients Consumers better educated (Blow, 1998) But Prescription Drug Problems Still Occur Because… Older adults: Misunderstand directions for use or purpose of meds Forget to take meds Take too much by accident or to get greater effect Prescribing practices need improvement: Drugs’ effects among older adults not understood Multiple drugs prescribed by multiple physicians Insufficient diagnosis for prescribing Meds prescribed for too long Insufficient monitoring of effects and compliance (Blow, 1998) Examples of Medication Issues Many medications and street drugs interact with alcohol (e.g., additive effects with sedative/hypnotics/benzodiazepines) Some drugs may cause delirium: Sedative/hypnotics (e.g., benzodiazepines) Analgesics (narcotics) Drugs with anticholinergic effects* (e.g., disopyramide used for arrhythmia) (Alagiakrishnan & Wiens, 2004) *These drugs block the action of acetylcholine, a neurotransmitter that helps nerve cells communicate. Recommended Limits for Alcohol Consumption Among Older Adults National Institute on Alcohol Abuse and Alcoholism People aged 65 and older: no more than one drink per day (NIAAA, 2000) TIP Consensus Panel Older men: No more than one drink per day; maximum of 2 drinks on any occasion Older women: Somewhat lower limits (Blow, 1998) Standard drink = 12 oz. beer; shot (1.5 oz.) hard liquor; 5 oz. wine; 4 oz. sherry, liqueur, or aperitif Examples of Warning Signs Preoccupation with Malnutrition/dehydr prescription drugs Unnecessary requests for prescription refills Uses more than prescribed Minor traffic accidents Unexplained bruises, burns, falls, fractures, accidents (Blow, 1998) ation Withdraws from normal social activities Poor personal hygiene/grooming Empty containers Hidden alcohol Expulsion from housing Avoids activities if Barriers to Problem Resolution Health care providers poorly educated about substance use disorders Symptoms mistaken for depression, dementia, etc. Medical appointments rushed Attitude that treatment won’t be effective (waste of time, resources) Older adults more likely to hide problem (shame) Families also ashamed (stigma) Professionals and family members attitude of “why not– life is short” Older adults less likely to seek treatment Desire to solve problems on their own (Blow, 1998) Ask Yourself These Questions: If someone died of a cocaine overdose, what would be your first thought about their age? If someone died of accidental overdose due to combined effects of Rx painkillers, benzodiazepines or antianxiety agents, and sleep aids, what would be your first thought about their age? Now consider this: A. Rock ‘n roll legend Ike Turner died of accidental cocaine toxicity (overdose) in January 2008 at age 76. Hypertensive cardiovascular disease and pulmonary emphysema were significant, contributing factors. B. Actor Heath Ledger died of an accidental overdose of prescription drugs (painkillers, anti-anxiety drugs, and sleeping pills) in February 2008 at age 28. Screening with the CAGE Have you ever felt you should Cut down on your drinking? Have people Annoyed you by criticizing your drinking? Have you ever felt bad or Guilty about your drinking? Have you ever had a drink first thing in the morning to steady your nerves or get rid of a hangover (Eye opener) (Ewing, 1984) Michigan Alcoholism Screening TestGeriatric Version (MAST-G) Sample of items: Does alcohol make you sleepy so that you fall asleep in your chair? After a few drinks, have you sometimes not eaten or been able to skip a meal because you don’t feel hungry? Have you ever increased your drinking after experiencing a loss in your life? (Source: Blow et al., 1992) © The Regents of the University of Michigan, 1991.The complete instrument is reprinted with permission in Blow, 1998. Health Screening Survey (HSS), Revised Sample items: In the last three months, have you been drinking alcoholic drinks at all (e.g., beer, wine, sherry, vermouth, or hard liquor). In the last three months, have you felt guilty or bad about: a. Your weight b. How much you smoke c. How much you drink d. How unfit you are (Source: Fleming & Barry, 1991) The complete instrument is reprinted with permission in Blow, 1998. Ideas for Improving Screening Teach health care providers, volunteers (Meals-on-Wheels), caretakers to screen. Ask alcohol/drug questions with health questions (“I’m wondering if alcohol may be the reason your diabetes isn’t responding as it should.”). Be non-confrontational, supportive, and show respect, but address denial and rationalization. Avoid stigmatizing terms like “alcoholic” or “drug abuser.” If older person cannot respond coherently, ask permission to speak with collaterals (e.g., family, friends). Use “brown bag approach” (bring all meds, Rx, OTC, herbs). Use preferred language and be aware of cultural issues. Take good social histories. (Blow, 1998) Consensus Panel Recommendation: “Every 60 year-old should be screened for alcohol and prescription drug abuse as part of his or her regular physical examination.” Screen again if physical symptoms indicated or older person undergoing major life changes. (Blow, 1998) Differential Diagnosis Obtain a medical history Obtain a family and social history Obtain a behavioral health, psychiatric history Obtain an alcohol and drug history Determine current medication/alcohol/other drug use Consider effects of all drugs being used Consider effects of chronic diseases (Center for Substance Abuse Prevention, 2002; McNeece & DiNitto, 2005) What are Substance Use Disorders? Pattern of use leading to clinically significant impairment or distress Abuse Dependence Obligations not met Tolerance Recurrent hazardous use Withdrawal Recurrent legal problems Larger amounts over longer time Continued use despite recurring Can’t cut down problems (One or more in 12-month period) More time using/recovering Important activities reduced/given up Recurrent physical or psychological problems (American Psychiatric Association, 2000) (Three or more in 12-month period) Substance Dependence Specify: Course Specifiers: With physiological Early full remission dependence: tolerance and/or withdrawal present Without physiological dependence: neither tolerance nor withdrawal present Early partial remission Sustained full remission Sustained partial remission On agonist therapy (medication) (American Psychiatric Association, 2000) In a controlled environment Applying DSM-IV Criteria to Older Adults Tolerance May not occur; small amounts can be a problem Withdrawal Larger amounts/ longer time May not occur in late onset Cognitive impairment impairs self monitoring Can’t cut down Same Low levels can be problem More time using/ giving up activities Reduced activities may mask detection Continued use despite problems May not understand problems are related to use even after medical advice (Barry, Blow & Oslin, 2002; Blow, 1998) Alternative Classifications for Older Adults At Risk: Pattern of alcohol use not causing problems yet but may bring about adverse consequences Problem Drinkers: Includes heavy drinkers/hazardous consumers and those who fit abuse and dependence categories (Blow, 1998) What are Substance-Induced Disorders? Substance Intoxication Substance Withdrawal Substance Induced: Delirium Persisting Dementia Persisting Amnestic Disorder Psychotic Disorder Mood Disorder Anxiety Disorder Sexual Dysfunction Sleep Disorder (American Psychiatric Association, 2000) Eleven Drug Classes in DSM-IV-TR 1. Alcohol 7. Inhalants 2. Amphetamines 8. Nicotine 3. Caffeine 4. Cannabis 5. Cocaine 6. Hallucinogens 9. Opioids 10.Phencyclidine (PCP) 11.Sedatives, hypnotics, and anxiolytics (American Psychiatric Association, 2000) Early vs. Late Onset Alcohol Problems Early Onset (more intractable) Late Onset (easier to treat) 2/3 of older alcoholics 1/3 of older alcoholics Disorder begins before age 40, Disorder begins later (after age Social supports less likely Former social drinkers or even More likely to More likely to often in 20s or 30s Drink to intoxication Have previous treatment Have legal, financial, other problems Have psychiatric comorbidity (mood & thought disorders) (Studies on early and late onset are discussed in Blow, 1998; Fingerhood, 2000) 40, 50, or 60) teetotalers Enter treatment due to crisis/recent loss/health Be in better physical/ psychological health Be depressed or lonely Deny problem Have social support Late Onset: Three Scenarios 1. Longtime “functional” alcoholics develop behavioral or cognitive impairment unrelated to alcohol use; can no longer function when drinking. 2. Social drinkers become more vulnerable to alcohol even when drinking same quantity/frequency. 3. Social drinkers increase quantity/frequency due to recent stressors (spouse’s death, retirement, disability). (Fingerhood, 2000) Dementia and Delirium Dementia: Marked loss in multiple areas of intellectual/cognitive functioning (e.g., memory, abstract thinking) that is chronic, progressive, and usually irreversible Delirium: Sudden or acute confusion that can be life threatening but generally reversible with medical treatment (Blow, 1998; also see American Psychiatric Association, 2000) Dementia Impaired short- & long-term memory, abstract thinking, & judgment Language disorder Inability to carry out motor activities Constructional difficulties Personality change Mood disturbances Loss of self-care ability (Blow, 1998; Center for Substance Abuse Prevention, 2002) Delirium Inability to appreciate/respond to environment normally Clouding of consciousness Reduced wakefulness Disoriented to time/space Increased motor activity (e.g., restless, plucking, picking) Impaired attention, concentration, memory Anxiety, suspicion, agitation Misinterpretations, illusions, hallucinations Disrupted thinking, delusions, speech abnormalities (Blow, 1998; Center for Substance Abuse Prevention, 2002) Causes: Dementia Most common causes: Alzheimer’s, vascular dementia, alcohol-related Metabolic toxic causes (e.g., organ system failure, hypoglycemia) Infectious causes (e.g., AIDS/HIV, encephalitis) Other causes include Parkinson’s, Lewy body dementia (Blow, 1998; Center for Substance Abuse Prevention, 2002) Causes: Delirium Intracranial: infections (e.g., meningitis, encephalitis), seizures, stroke, subdural hematomas, tumors Extracranial: anesthesia, drug-drug or alcohol-drug interactions, alcohol or drug intoxication and withdrawal, hip fracture, infections, dehydration, malnutrition, diabetes, depression, etc. (Blow, 1998; Center for Substance Abuse Prevention, 2002) Wernicke-Korsakoff Syndrome Loss of specific brain functions due to thiamine deficiency; often associated with chronic alcohol dependence Wernicke’s encephalopathy: Damage to nerves in CNS (brain, spinal cord) and peripheral nervous system (rest of body). Thiamine (vitamin B) deficiency common in alcoholics; heavy use prevents absorption. Korsakoff’s syndrome or psychosis: Develops as Wernicke’s symptoms remit. Symptoms: vision (double vision, eye movement abnormalities, dropping eyelids); ataxia (unsteady, uncoordinated walking); memory loss (may be profound), inability to form new memories; confabulation (makes up stories that may seem believable at first), and hallucinations (Medline Plus, 2006) Substance Use Disorders Often Comorbid with Psychiatric Disorders Mood Disorders But memory impairment in major depressive episode may be mistaken for signs of dementia Alcohol and other sedatives (depressant drugs) may induce depression Anxiety Disorders Personality Disorders Potential for “self” medication (See Blow, 1998; Center for Substance Abuse Prevention,2002) Cultural Considerations In a given culture, what factors are believed to cause alcohol/drug problems--genetics, biology, psychology, culture, morality, choice, curses? How much stigma is attached to alcohol/drug problems? What are cultural considerations for screening, interventions, and treatment? (See McNeece & DiNitto, 2005) Example: Mexican Americans Possible “causes”: Fatalism Moral weakness Culture-bound syndromes/illnesses (e.g., susto, nervios) Stigma: Greater for women Men entitled to drink but not irresponsibly More stigma attached to illicit drug use (See, for example, Alvarez & Ruiz, 2001; Kail & DeLaRosa, 1999; McNeece & DiNitto, 2005) Example: Mexican Americans (cont.) Screening/Intervention Acculturation/acculturative stress Language Values (personalismo, respeto, familismo, confianza, dignidad, marianismo, fatalismo, machismo) Religion and clergy Health insurance (high rates of uninsured) Concrete services (meet basic needs) Fiestas and celebrations Folk medicine (curanderos/curanderas) (Alvarez & Ruiz, 2001; Kail & DeLaRosa, 1999; McNeece & DiNitto, 2005) Assess Stage of Change Precontemplation: lacks awareness of problem; no intent to change Contemplation: aware of problem; considers change Preparation: intends to change soon Action: successfully makes changes Maintenance: continues to change and prevent relapse (Connors, Donovan, & DiClemente, 2001; Prochaska, DiClemente, & Norcross, 1992) Elements of Brief Intervention Customized feedback based on screening and assessment Where patient fits in terms of drinking norms for his/her age group Discuss client’s reasons for drinking Discuss consequences of heavy drinking Discuss reasons to cut down or quit Discuss sensible drinking limits and strategies for cutting down or quitting Drinking agreement in form of a prescription Discuss how to cope with risky situations Summarize session (Barry et al., 2002; Blow, 1998) FRAMES Approach to Brief Intervention Give feedback about personal risk from assessment results Emphasize personal responsibility (patient’s choice to reduce/stop drinking) Give clear advice about how to change drinking Provide a menu of change options Use an empathic counseling style (be warm, reflective, understanding) Encourage client self-efficacy and optimism Establish a drinking goal (Miller & Rollnick, 1991; Miller & Sanchez, 1994) Brief Intervention with Older Adults Appreciate the individual for meeting with you Identify health goals and other goals Summarize health habits Educate on standard drink and types of older drinkers Explore reasons older person drinks and reasons to cut down or quit Develop a drinking agreement Plan for situations that may trigger drinking (Center for Substance Abuse Prevention, 2002; Fleming, Manwell, Barry, Adams, & Stauffacher, 1999) Additional Treatment Approaches Detoxification Inpatient, day treatment/partial hospitalization, extended outpatient treatment, case management as needed Alcoholics Anonymous and other mutual-help groups Community support programs or groups (Blow, 1998; Vinton & Wambach, 2005) Strategies for Improving Substance Use Disorder Treatment for Older Adults Include older person as full partner in recovery Age-specific treatment that is supportive, nonconfrontational, builds self-esteem Focus on coping with depression, loneliness, loss Rebuild social support network Pace, content, environment appropriate for older persons Staff experienced and interested in serving older adults Links with medical, social, institutional and other services for older people (Blow, 1998) More Strategies Assure confidentiality to extent possible Include smoking cessation Provide transportation Hearing devices, large print materials Follow principles or work with older clients Address denial Motivate, inspire Provide hope and encouragement (Blow, 1998) Remember It’s never too late to develop an alcohol or drug problem. It’s never too late (or too early) to intervene. AND It’s never too late to recover. References Adams, W. L., Barry, K. L., & Fleming, M. F. (1996). Screening for problem drinking in older primary care Patients. Journal of the American Medical Association, 276(24), 1964-1967. Alagiakrishnan, K., & Wiens, C. A. (2004). An approach to drug induced delirium in the elderly. Postgraduate Medical Journal, 80, 388-393. Alvarez, L. R., & Ruiz, P. (2001). Substance abuse in the Mexican American population. In S. L. A. Straussner, Ethnocultural factors in substance abuse treatment (pp. 111-136). New York: Guilford Press. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders, 4th ed., text revision. Washington, DC: Author. Barry, K. L., Blow, F. C., & Oslin, D. W. (2002). Substance abuse in older adults: Review and recommendations for education and practice in medical settings. In M. R. Haack & H. Adger, Jr. (Eds.), Strategic plan for interdisciplinary faculty development: Arming the nation’s health professional for a new approach to substance use disorders. Substance Abuse, 23(3) supplement, 105-131. Blow, F. C. (1998). Substance abuse among older adults, Treatment Improvement Protocol (TIP) Series 26. DHHS Publication No. (SMA) 98-3179. Rockville, MD: Substance Abuse and Mental Health Services Administration. Retrieved from http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=hstat5.chapter.48302. Blow, F. C., Brower, K. J., Schulenberg, J. E., Demo-Dananberg, L. M., Young, J. P., & Beresford, T. P. (1992). The Michigan Alcoholism Screening Test-Geriatric Version (MAST-G): A new elderly-specific screening instrument. Alcoholism: Clinical and Experimental Research, 16, 372. References (cont.) Center for Substance Abuse Prevention. (2002). At any age, it does matter: Substance abuse and older adults (for professionals). Rockville, MD: Substance Abuse and Mental Health Services Administration. Retrieved from http://pathwayscourses.samhsa.gov/aaap/aaap_intro.htm. Colliver, J. D., Compton, W. M., Gfroerer, J. C., & Condon, T. (2006). Projecting drug use among aging baby boomers in 2020. Annals of Epidemiology, 16(4), 257-265. Connors, G. J., Donovan, D. M., & DiClemente, C. C. (2001). Substance abuse treatment and the stages of change: Selecting and planning interventions. New York: Guilford Press. Ewing, J. A. (1984). Detecting alcoholism: The CAGE questionnaire. Journal of the American Medical Association, 252, 1905-1907. Fingerhood, M. (2000). Substance abuse in older people. Journal of the American Geriatrics Society, 48, 985-995. Fleming, M. F., & Barry, K. L. (1991). A three-sample test of a masked alcohol screening questionnaire. Alcohol and Alcoholism, 26(1), 81-91. Fleming, M. F., Manwell, L B., Barry, K. L., Adams, W; Stauffacher, E. A. (1999). Brief physician advice for alcohol problems in older adults: Randomized community-based trial. Journal of Family Practice, 48(5), 378-384. Kail, B. L., & DeLaRosa, M. (1999). Challenges to treating the elderly Latino substance abuser: A not so hidden agenda. Journal of Gerontological Social Work, 30(1/2), 123-141. McNeece, C. A., & DiNitto, D. M. (2005). Chemical dependency: A systems approach (3rd ed.). Boston Allyn & Bacon. References (cont.) Medline Plus. (2006, September 10). Wernicke-Korsakoff syndrome. Retrieved from http://www.nlm.nih.gov/medlineplus/ency/article/000771.htm. Miller, W. R., & Rollnick, S. (1991). Motivational interviewing. New York: Guilford Press. Miller, W. R., & Sanchez, V. C. (1994). Motivating young adults for treatment and lifestyle change. In G. S. Howard & P. E. Nathan (Eds.). Issues in alcohol use and misuse by young adults (pp. 55-81). Notre Dame, IN: University of Notre Dame Press. National Institute on Alcohol Abuse and Alcoholism. (2000). 10th special report to the U.S. Congress on alcohol and health. Washington, DC: U.S. Department of Health and Services. Office of Applied Studies. (2005). Substance use among older adults: 2002 and 2003 update. The NSDUH Report. Rockville, MD: Substance Abuse and Mental Health Services Administration. Prochaska, J. O., Di Clemente, C. C., & Norcross, J. C. (1992). In search of how people change: Applications to addictive behaviors. American Psychologist, 47, 1102-1114. Vinton, L., & Wambach, K. G. (2005). Alcohol and drug use among elderly people. In C. A. McNeece & D.M. DiNitto, Chemical dependency: A systems approach (3rd ed., pp. 484-502). Boston: Allyn & Bacon.