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The Respiratory System By: Jenny, Priti, & Lindsay Functions of the System The main function of the respiratory system is rather simple in concept: to bring in oxygen from the atmosphere and get rid of carbon dioxide from the blood.You breathe in oxygen rich air and you breathe out carbon dioxide rich air. When you breathe in the oxygen rich air, it goes through the nasal cavity where dust and dirt are swept up by tiny hairs. Since oxygen and carbon dioxide are gases, the process of bringing one in and excreting the other is called gas exchange. While the intake of oxygen and removal of carbon dioxide are the primary functions of the respiratory system, it plays other important roles in the body. The respiratory system helps regulate the balance of acid and base in tissues, a process crucial for the normal functioning of cells. It protects the body against disease-causing organisms and toxic substances inhaled with air. The respiratory and circulatory systems work together to deliver oxygen to cells and remove carbon dioxide in a two-phase process called respiration. The first phase of respiration begins with breathing in, or inhalation. Inhalation brings air from outside the body into the lungs. Oxygen in the air moves from the lungs through blood vessels to the heart, which pumps the oxygen-rich blood to all parts of the body. Oxygen then moves from the bloodstream into cells, which completes the first phase of respiration. Functions of the System Cont. In the cells, oxygen is used in a separate energy-producing process called cellular respiration, which produces carbon dioxide as a byproduct. The second phase of respiration begins with the movement of carbon dioxide from the cells to the bloodstream. The bloodstream carries carbon dioxide to the heart, which pumps the carbon dioxide-laden blood to the lungs. In the lungs, breathing out, or exhalation, removes carbon dioxide from the body, thus completing the respiration cycle. Problems and Diseases Bronchitis • • • • • • Inflammation of the bronchi (air passages connecting the windpipe with the sacs of the lung). Symptoms are fever, coughing, spitting, and a severe cold. This could continue for months and return each year. Cigarette smoking and environmental pollution are the main causes of bronchitis. Also caused by various infections which damage and weaken the bronchial walls The best treatment for bronchitis is prevention which means no smoking. Various antibiotics are also given. Bronchitis is a preventable disease rare in non-smokers. Infants and children generally get it more often than adults. Tuberculosis • The disease is caused by Mycobacterium tuberculosis, a rod- shaped bacterium. • Symptoms of TB include coughing, chest pain, shortness of breath, loss of appetite, weight loss, fever, chills, and fatigue. • Children and people with weakened immune systems are the most susceptible to TB. Half of all untreated TB cases are fatal. • Vaccines, such as the Bacillus Calmette Guerin (BCG) are the most effective in preventing tuberculosis. • Ventilation systems lessen the chance of infection by dispersing the bacteria. Ultraviolet lighting also reduces, but does not eliminate, the threat of infection by killing TB bacteria in confined spaces. Problems and Diseases Cont. WHAT IS PNEUMONIA? Pneumonia is a serious infection or inflammation of your lungs. The air sacs In the lungs fill with pus and other liquid. Oxygen has trouble reaching your blood. If there is too little oxygen in your blood, your body cells can't work properly. Because of this and spreading infection through the body pneumonia can cause death. CAUSES OF PNEUMONIA Pneumonia is not a single disease. It can have over 30 different causes. There are five main causes of pneumonia: • Bacteria • Viruses • Mycoplasmas • Other infectious agents, such as fungi – including pneumocystis • Various chemicals WHAT IS EMPHYSEMA? Emphysema is a condition in which there is over-inflation of structures in the lungs known as alveoli or air sacs. This over-inflation results from a breakdown of the walls of the alveoli, which causes a decrease in respiratory function (the way the Lungs work) and often, breathlessness. CAUSES OF EMPHYSEMA The elastic fibers in the lung allow the lungs to expand and contract. When the chemical balance is altered, the lungs lose the ability to protect themselves against the destruction of these elastic fibers. This is what happens in emphysema. Asthma WHAT IS ASTHMA? Asthma is a lung disease. It can be life threatening. Asthma is chronic. In other words, you live with it every day. Asthma causes breathing problems. These breathing problems are called attacks or episodes of asthma. AN ASTHMA ATTACK Doctors are not exactly certain how you get asthma. But they do know that once you have it, your lungs react to things that can start an asthma attack. For instance, when you have asthma, you might get an asthma attack when you have a cold (or some other kind of respiratory infection). Or, you might get an attack when you breathe something that bothers your lungs (such as cigarette smoke, dust or feathers). When this happens, three changes take place in your lungs: Cells in your air tubes make more mucus than normal. This mucus is very thick and sticky. It tends to clog up the tubes. The air tubes tend to swell, just as skin swells when you get a scrape. The muscles in your air tubes tighten. These changes cause the air tubes to narrow. This makes it hard to breathe. Asthma attacks may start suddenly. Or they may take a long time, even days, to develop. Attacks can be severe, moderate or mild. What Our System Looks Like This system includes the lungs, pathways connecting them to the outside environment, and structures in the chest involved with moving air in and out of the lungs. Air enters the body through the nose, is warmed, filtered, and passed through the nasal cavity. Air passes the pharynx. The upper part of the trachea contains the larynx. The vocal cords are two bands of tissue that extend across the opening of the larynx. After passing the larynx, the air moves into the bronchi that carry air in and out of the lungs. Bronchi are reinforced to prevent their collapse and are lined with ciliated epithelium and mucus-producing cells. Bronchi branch into smaller and smaller tubes known as bronchioles. Bronchioles terminate in grape-like sac clusters known as alveoli. Alveoli are surrounded by a network of thin-walled capillaries. Only about 0.2 µm separate the alveoli from the capillaries due to the extremely thin walls of both structures. More Diagrams Ventilation is the mechanics of breathing in and out. When you inhale, muscles in the chest wall contract, lifting the ribs and pulling them, outward. The diaphragm at this time moves downward enlarging the chest cavity. Reduced air pressure in the lungs causes air to enter the lungs. Exhaling reverses theses steps. The lungs are large, lobed, paired organs in the chest (also known as the thoracic cavity). Thin sheets of epithelium (pleura) separate the inside of the chest cavity from the outer surface of the lungs.The bottom of the thoracic cavity is formed by the diaphragm. New Technology A University of Pittsburgh researcher who has developed a device that functions like a temporary set of of lungs told a group of heart and lung transplant surgeons today that such technology could have a tremendous impact for the nearly 750,000 patients with emphysema, chest trauma or acute respiratory distress, about 150,00 of whom die each year. April 27, 2001 researchers from the university of Pittsburgh led to the development of the Hattler Respiratory Catheter. It’s designed that it can effectively carbon dioxide and oxygen in patients with comprised lungs, allowing their own lungs to rest and heal. The intravenous devise is inserted through a vein in the leg and positioned in the main vein that returns blood to the heart. The artificial will also help people suffering from chronic obstructive lung disease, in which lungs are damaged. The artificial lung will take over the job of putting fresh oxygen in blood for up to two weeks. A lung transplant is donated from a human who has been declared brain-dead but remains on life-support. Tissue matches must be made to assure the patients best chance of fighting off rejection of the transplanted tissue. While the patient is deep asleep and pain-free, an incision is made through the sternum. Tubes are used to re-route the blood to a heart-lung bypass machine to keep the blood oxygenated and circulating during the surgery. Factoids Your lungs contain almost 1500 miles of airways and over 300 million alveoli. Every minute you breathe in 13 pints of air. Plants are our partners in breathing. We breathe in air, use the oxygen, and release carbon dioxide. Plants take in carbon dioxide and release oxygen. Thank God! People tend to get more colds in the winter because we’re indoors more often and in close proximity to other people. When people sneeze, cough and breathe– germs go flying! Bibliography http://www.lungusa.org http://www.eb.com:180/ http://tmx.com/fun/roadmap/respirat.htm Frost, Helen . The Respiratory System. Mankato, MN: Pebble Books, 2001. Stille, Darlene R. The Respiratory System. New York: Children's P, 1997. Sebel, Peter . Respiration, the breath of life . New York: Torstar Books, 1985. THE END