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Mitosis and cellular division How do little elephants grow up to be BIG elephants? Reproduction is the process by which organisms produce more of their own kind. Think about it – Without reproduction, all life on earth would no longer exist. Only one parent is involved. Offspring are genetically identical to their parents. All cells that come from a single cell are genetically identical to it and to each other; they are all clones. We have two types of cells in our body a) Gamete cells – sperm and egg cells b) Somatic cells – all body cells except reproductive cells (examples- skin cells, hair cells, nerve cells etc) All somatic cells reproduce by a process called MITOSIS. This is ASEXUAL reproduction. All sexual cells are produced by a process called MIOSIS. This is SEXUAL reproduction The process of asexual reproduction begins after a sperm fertilizes an egg. Skin cancer - the abnormal growth of skin cells - most often develops on skin exposed to the sun. Cell that reproduce by asexual reproduction reproduce constantly. We are going to look at how somatic cells reproduce so that each new cell has the same complete set of instructions (DNA). That process is called Asexual Reproduction Mitosis Mitosis is the process in which the nucleus divides to form two new nuclei. The two new cells created are identical. 11 11 A chromosome is a structure composed of DNA. Each chromosome has a different form. Humanes have 46 chromosomes in the form of 23 pairs found in the nucleus of each of our cells. Chromosomes are particularly visibles during the division process of the cell. Different species have different numbers of chromosomes. - Humans have 46 - Chicken have 78 - Mosquito have 6 - Rice has 24 Segments of DNA determine a particular hereditary trait. A gene is on a specific spot on each chromosome. We can divide the life cycle into four parts: › 1) Growth (G1) › 2) The synthesis and replication of chromosomes (S) › 3) Preparation for division (G2) › 4) Mitosis (M)– cell division Cell Cycle and Mitosis [3D Animation] https://www.youtube.com/watch?v=Jc ZQkmooyPk Mitosis: The Amazing Cell Process that Uses Division to Multiply! https://www.youtube.com/watch?v=g wcwSZIfKlM Animated Mitosis Cycle http://www.cellsalive.com/mitosis.htm • Interphase • Prophase • Metaphase • Anaphase • Telophase & Cytokinesis Interphase Prophase Metaphase Anaphase Cell division Telophase S Interphase G2 G1 M Chromosomes are copied (# doubles) • Chromosomes appear as threadlike coils (chromatin) at the start, but each chromosome and its copy(sister chromosome) change to sister chromatids at end of this phase • Nucleus CELL MEMBRANE Cytoplasm Chromatide Identical chromatide Chromosome Centromere Two identical chromosomes Replication Anaphase The centromere is what holds these two identical chromosomes together. Animal Cell Plant Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm chromatin • • • Mitosis begins (cell begins to divide) Centrioles (or poles) appear and begin to move to opposite end of the cell. Spindle fibers form between the poles. Centrioles Sister chromatids Spindle fibers Animal Cell Plant Cell Spindle fibers Centrioles Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm • Chromatids (or pairs of chromosomes) attach to the spindle fibers. Centrioles Spindle fibers Animal Cell Plant Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm • Chromatids (or pairs of chromosomes) separate and begin to move to opposite ends of the cell. Centrioles Spindle fibers Animal Cell Plant Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm • • • • Two new nuclei form. Chromosomes appear as chromatin (threads rather than rods). Nuclear membrane reforms Mitosis ends. Nuclei Chromatin Nuclei Animal Cell Plant Cell Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm • • Cell membrane moves inward to create two daughter cells – each with its own nucleus with identical chromosomes. Division of the cytoplasm In plant cells, a cell plate forms across the centre of the cell, forming a new cell wall between the two new cells. Mitosis Click the picture above! Animal Mitosis -- Review Interphase Prophase Metaphase Anaphase Telophase Interphase Plant Mitosis -- Review Interphase Prophase Metaphase Anaphase Telophase Interphase 47 48 48 http://www.cellsalive.com/mitosis.htm