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Anxiety & Somatic Symptom Disorder: CASE STUDY WI Alliance of Child Psychiatry & Pediatrics (WACPP) James Meyer MD 4/14/2015 Disclosure Statement I, James Meyer, M.D., do not have any relevant financial interest or other relationship(s) with a commercial entity producing health-care related product and/or services. I will indicate during this presentation when a medication use or dosage is other than an FDA approved treatment. Case: Angela Presents at age 16 yrs with both parents for second opinion with concern regarding daily headaches that interfere with attendance at school. Headaches are daily described as tight ache to throbbing present all day every day. No night waking but may affect falling asleep. Has a HA if she wakes at night which happens 1-2 times per week. Does not think she wakes b/o HA. Light might bother but no visual spots or vision change. Loud noise may bother but no ringing in ears. Case: Angela May get nausea but no vomiting, paresthesias, neck pain and no facial flushing, eye tearing, rhinorrhea or nasal congestion. Not correlating with meals or specific foods and drinks a lot of fluid do to orthostatic hypotension with prior positive tilt table test. Not worse with menses or hormonal RX. No concussion or whiplash Denies a specific worry as to cause of HA Case: Angela HA RX’s CT and MRI of brain in past 18months=WNL Prior amitriptyline up to 50mg at HS. Prior beta blocker (may have helped orthostatic low BP) but not HA. Prior topiramate bid. Recent Botox injection-changes HA but not getting rid of them. Counseling regarding parents divorce. Case: Angela PMHx No prenatal problems. No major early colic, developmental or temperament issues but issues with difficult transitions (new day care, start school, separation from parent, etc. ). Extensive GI evaluation age 9-10 for recurrent abdomen pain (no formal diagnosis and all labs/biopsies were normal) Case: Angela PMHx Exercise induced asthma diagnosed 2 years ago for feeling like she can’t catch her breath/take a deep breath in BB games (not practice). Progresses to feeling scared, fears she will die and has had paresthesias. Early response to albuterol used prior to exercise. Over time felt that it was not working and Advair was added(250/50). Has quit BB. Regional Pain Syndrome after minor foot injury last year. Case: Angela Maximum stress is school: good student (A’s & B’s) but hard to keep up and misses 2-5 days per week. Missed 80 days last year. Peers tease her about playing hooky. Worries about everything-needs to know what is coming at her in advance. Likes routines. Upset with worry if parents not home when they are expected. Sense of SOB, sweats and dread out of blue 1X/month. Relieved by getting away from people. Somewhat meticulous with order/neatness. No abuse, disordered eating or suspected drugs. Case: Angela Social Hx Splits time between mom and dad/dads GF homes. Parents divorced one year ago. Two older full siblings (one away at college this year) and one infant half paternal sib. Mom was a homemaker but now working as a secretary. Dad a teacher. Misses more school when staying with her mom. 11th grade A & B student. Pushes herself hard for grades. Feels she does not concentrate well. Does well on statewide achievement tests. No suspected ADD/ADHD or learning disability. Has a few close friends. Not dating. Case: Angela FHx Mom on meds for anxiety/depression over past 10 years (citalopram with occasional lorazepam). Has migraines as does MGM. Maternal aunt with life long panic attacks. Sister allergic rhinitis but no family member with asthma or EIA. No FHx of sudden death, arrythmia, early heart disease. Case: Angela EXAM Mom seems worried about her daughter. Dad seems frustrated with his daughters many physical symptoms. Normal exam with stable weight/HT trend No suggestion of pallor/anemia, thyroid dysfunction, obstructive nasal breathing, or other medical conditions. Jumps up & down 100x with good effort and no symptoms. No change in pre to post peak flow. Case: Angela Prior LABs Labs: WNL CBC with differential, ferritin 12 (nl >14), TSH, MPC, ESR and Lyme titer. Normal spirometry with negative methacholine challenge. Prior normal EKG. Normal Neuro imaging. x x x x x x x 2 15 17 Total score: Average score 4.9 >10 + signif. anxiety >15 + severe anxiety Source: Spitzer RL, Kroenke K, Williams JBW, Lowe B. A brief measure for assessing generalized anxiety disorder. Arch Inern Med. 2006;166:1092-1097. CASE: Angela Screen for Child Anxiety Related Disorders (SCARED) Child Version score is 40 Parent Version score is: mom 44, dad 36 Primary points being attained by noting: not enjoy being around people does not know, HA’s at school, scared sleeping away from home, feeling nervous, gets shaky, heart racing, looking nervous, worries about being liked, being as good as other kids, about things that have already happened, and something bad happening to parents. A SCARED score of over 30 indicates significant anxiety (normal is less than 25). Generalized Anxiety Disorder The Diagnostic and Statistical Manual of Mental Disorders (4th Ed; DSM-IV) Criteria for diagnosis A. At least 6 months of "excessive anxiety and worry" about a variety of events and situations. B. There is significant difficulty in controlling the anxiety and worry or major struggle to regain control, relax, or cope with the anxiety and worry. C. The presence for most days over the previous six months of 3 or more (only 1 for children) of the following symptoms: 1. Feeling wound-up, tense, or restless 2. Easily becoming fatigued or worn-out 3. Concentration problems 4. Irritability 5. Significant tension in muscles 6. Difficulty with sleep. D. The symptoms cause "clinically significant distress" or problems functioning in daily life (home, school, peers, relationships and work). E. The condition is not due to a substance, medical or other mental health issue Case: Diagnosis Angela Chronic daily headache Generalized Anxiety Disorder Plan of Care: Reassurance- symptoms are real but exacerbated by stress and bodies physical response to stressors. Relaxation exercises. Mindfulness training. Therapy/counseling Medication Case: Angela Treatment Therapy/counseling: Refer for counseling to address role of stress response in her physical symptoms. Will re-focus thoughts on positive thoughts and actions to relieve symptoms. Family to avoid over focus on symptoms. Address school stressors. Medication- SSRI citalopram 10mg increasing to 20mg after 1 week. Discuss aspects of use, side effects and risks including the black box warning and needed follow up. Provide family with a written handout on SSRI’s and anxiety. Case: Angela F/U Follow upPhone update in 1 week to screen for: - red flags (agitated, suicidal thoughts, major sleep issues) - basic side effects (tremor, nausea, bowel changes, weight/appetite, fatigue/sleep issues) - compliance - any other concerns Appointment in 2 weeks for review of above plus thoughts and actions that patient family have used to decrease stress and focus on positives. Case: Follow up at 2 weeks Angela Some generalized improvement noted by patient and parent. No ill effects of SSRI’s and compliant. Phone follow up at 4 weeks without concerns believe med is helping Follow up at 6 weeks Overall less stressed and overwhelmed Has been meeting with counselor every 2 weeks focusing on relaxation exercises, activities which calm her down and relieve worried thoughts Has been doing better with school attendance and less HA complaints. Contact Information Dr. James Meyer Marshfield Clinic [email protected] Dr. Joseph O’Grady, Jr. 715-387-5251 [email protected] Medical College of WI 414-955-8935 WI Counsel of Child/Adolescent Psychiatrists