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Panic Attacks! Dr. Michael Tulloch Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 Slides & Handouts by Karen Clay Rhines, Ph.D. Slides by M. Tulloch, Ph.D. 1 Attack! "For me, a panic attack is almost a violent experience. I feel disconnected from reality. I feel like I'm losing control in a very extreme way. My heart pounds really hard, I feel like I can't get my breath, and there's an overwhelming feeling that things are crashing in on me." "I was sitting in a business seminar in a hotel and this thing came out of the blue. I felt like I was dying." "In between attacks there is this dread and anxiety that it's going to happen again. I'm afraid to go back to places where I've had an attack. Unless I get help, there soon won't be anyplace where I can go and feel safe from panic." http://www.nimh.nih.gov/publicat/anxiety.cfm Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 Slides by M. Tulloch, Ph.D. 2 Panic Attack Facts Panic attacks can occur at any time, even during sleep. An attack usually peaks within 10 minutes, but some symptoms may last much longer. Panic disorder affects about 6 million American adults1 Panic disorder is twice as common in women as men.2 Panic attacks often begin in late adolescence or early adulthood,2 Not everyone who experiences panic attacks will develop panic disorder. Many people have just one attack and never have another. The tendency to develop panic attacks appears to be inherited.3 Panic disorder is often accompanied by other serious problems, such as depression, drug abuse, or alcoholism.4,5 Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 http://www.nimh.nih.gov/publicat/anxiety.cfm 3 Risk Factors Adolecence or early adulthood Major life transitions perceived as stressful Graduating from college, getting married, having a first child Genetics If a family member has panic disorder, you have an increased risk Especially during a time in your life that is particularly stressful. Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 Slides by M. Tulloch, Ph.D. 4 Untreated Outcomes People who have full-blown, repeated panic attacks can become very disabled by their condition and should seek treatment before they start to avoid places or situations where panic attacks have occurred. For example, if a panic attack happened in an elevator, someone with panic disorder may develop a fear of elevators that could affect the choice of a job or an apartment, and restrict where that person can seek medical attention or enjoy entertainment. Some people's lives become so restricted that they avoid normal activities, such as grocery shopping or driving. About one-third become housebound or are able to confront a feared situation only when accompanied by a spouse or other trusted person. When the condition progresses this far, it is called agoraphobia, or fear of open spaces. Comer, Fundamentals of Abnormal Psychology, http://www.nimh.nih.gov/publicat/anxiety.cfm 5e – Chapter 4 5 Panic Disorder Panic, an extreme anxiety reaction, can result when a real threat suddenly emerges The experience of “panic attacks,” however, is different Panic attacks are periodic, short bouts of panic that occur suddenly, reach a peak, and pass Sufferers often fear they will die, go crazy, or lose control Attacks happen in the absence of a real threat Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 6 Panic Disorder Anyone can experience a panic attack But some people have panic attacks Repeatedly Unexpectedly Without apparent reason Diagnosis: Panic disorder Sufferers also experience dysfunctional changes in thinking and behavior as a result of the attacks Example: sufferer worries persistently about having an attack; plans behavior around possibility of future attack Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 7 Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 8 Panic Disorder Often (but not always) accompanied by agoraphobia From the Greek “fear of the marketplace” Afraid to leave home and travel to locations from which escape might be difficult or help unavailable Intensity may fluctuate There has only recently been a recognition of the link between agoraphobia and panic attacks (or panic-like symptoms) [But DON”T use this as diagnostic!] Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 9 Panic Disorder Two diagnoses: panic disorder with agoraphobia; panic disorder without agoraphobia ~3% of U.S. population affected in a given year ~5% of U.S. population affected at some point in their lives Likely to develop in late adolescence and early adulthood Women are twice as likely as men to be affected All ethnic groups are vulnerable to panic disorder ~ 35% of those with panic disorder are in treatment Slide modified by M. Tulloch, Ph.D. Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 10 Different from other Phobias Phobias that people with panic disorder develop do not come from: Fears of actual objects Fears of real events events Panic Disorders come from Fear of having another attack “Triggers” People will avoid certain objects or situations because They fear that these things will trigger another attack Classical Conditioning Fear Response paired with place/object/person/situation Generalization Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 Slides by M. Tulloch, Ph.D. 11 Panic Disorder: The Biological Perspective What biological factors contribute to panic disorder? Neurotransmitter responsible is believed to be norepinephrine Irregular in people with panic attacks Research suggests that panic reactions are related to changes in norepinephrine activity in the locus ceruleus Although norepinephrine is clearly linked to panic disorder, what goes wrong isn’t exactly understood May be excessive activity, deficient activity, or some other defect Other NTs and brain circuits seem to be involved Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 12 Panic Disorder: The Biological Perspective It is also unclear why some people have such abnormalities in norepinephrine activity Inherited biological predisposition is one possibility Prevalence should be (and is) greater among close relatives Among monozygotic (MZ, or identical) twins = 24% Among dizygotic (DZ, or fraternal) twins = 11% Issue is still open to debate Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 13 Panic Disorder: The Biological Perspective In the 1960s, it was recognized that people with panic disorder were not helped by benzodiazepines, but were helped by antidepressants Researchers worked backward from their understanding of antidepressant drugs [Which is still relatively poor] See Am J Psychiatry 161:7, July 2004 for an interesting discussion of the appropriate use of benzodiazepines vs SSRIs. Apparently, current clinical experience is that the former is appropriate for treatment of symptoms but is subject to abuse so that SSRIs are more suitable for recurrent attacks and long term prophylactic treatment. Slide modified by M. Tulloch, Ph.D. Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 14 Panic Disorder: The Biological Perspective Drug therapies Antidepressants are effective at preventing or reducing panic attacks Function at norepinephrine receptors in the panic brain circuit Bring at least some improvement to 80% of patients with panic disorder ~50% recover markedly or fully Require maintenance of drug therapy; otherwise relapse rates are high Some benzodiazepines (especially Xanax [alprazolam]) also have proved helpful Disagrees with previous slide Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 15 Panic Disorder: The Biological Perspective Drug therapies Both antidepressants and benzodiazepines are also helpful in treating panic disorder with agoraphobia Break the cycle of attack, anticipation, and fear Combination treatment (medications + behavioral exposure therapy) may be more effective than either treatment alone Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 16 Venlafaxine: Mechanism of Action Is thought to work by strongly inhibiting reuptake of serotonin (or 5-HT) strongly inhibiting reuptake of norepinephrine weakly inhibiting the reuptake of dopamine It is thought that increasing the available amount of these neurotransmitters helps individuals suffering from depression. However, the medication's full mechanisms of action are not entirely understood. Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 17 Venlafaxine (SSRI) may cause side effects that mimic panic attacks * change in ability to taste food * loss of appetite * weight loss * uncontrollable shaking of a part of the body * pain, burning, numbness, or tingling in part of the body * muscle tightness * twitching * yawning * sweating * hot flashes or flushing * frequent urination * difficulty urinating * sore throat, chills, or other signs of infection * drowsiness * weakness or tiredness * dizziness * headache * nightmares * anxiety * nausea * vomiting * stomach pain * constipation * diarrhea * gas * heartburn * burping * dry mouth Caution * ringing in the ears * changes in sexual desire or ability * enlarged pupils Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 Slides by M. Tulloch, Ph.D. 18 Panic Disorder: The Cognitive Perspective Cognitive theorists and practitioners recognize that biological factors are only part of the cause of panic attacks In their view, full panic reactions are experienced only by people who misinterpret bodily events Cognitive treatment is aimed at correcting such misinterpretations Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 19 Panic Disorder: The Cognitive Perspective Misinterpreting bodily sensations Panic-prone people may be overly (or especially) sensitive to certain bodily sensations and may misinterpret them as signs of a medical catastrophe; this leads to panic Why might some people be prone to such misinterpretations? One possibility: Experience more frequent or intense bodily sensations Another possibility: Experience abnormal sensations Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 20 Panic Disorder: The Cognitive Perspective Misinterpreting bodily sensations Panic-prone people also have a high degree of “anxiety sensitivity” They focus on bodily sensations much of the time, are unable to assess the sensations logically, and interpret them as potentially harmful Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 21 Panic Disorder: The Cognitive Perspective Cognitive therapy Attempts to correct people’s misinterpretations of their bodily sensations Step 1: Educate clients About panic in general About the causes of bodily sensations About their tendency to misinterpret the sensations Step 2: Teach clients to apply more accurate interpretations (especially when stressed) Step 3: Teach clients skills for coping with anxiety Examples: relaxation, breathing Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 22 Panic Disorder: The Cognitive Perspective Cognitive therapy May also use “biological challenge” procedures to induce panic sensations Induce physical sensations which cause feelings of panic: Jump up and down Run up a flight of steps Practice coping strategies and making more accurate interpretations Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 23 Panic Disorder: The Cognitive Perspective Cognitive therapy is often helpful in panic disorder 85% of treated patients are panic-free for two years compared with 13% of control subjects Only sometimes helpful for panic disorder with agoraphobia At least as helpful as antidepressants Combination therapy may be most effective Still under investigation Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 24 Treatment Approaches Cognitive Restructuring Cognitive Therapy Interoceptive Exposure Relaxation Techniques Medication Support Groups Relaxation Techniques Based upon materialoffrom © 2007 American Comer, Fundamentals Abnormal Psychology, 5e –Psychological Chapter 4 Association 25 Treatment - Info The first part of therapy is largely informational Many people are greatly helped by simply understanding exactly what panic disorder is and how many others suffer from it. Many people who suffer from panic disorder are worried that their panic attacks mean they're 'going crazy' or that the panic might be or induce a heart attack. 'Cognitive restructuring' (changing one's way of thinking) helps people replace those thoughts with more realistic, positive ways of viewing the attacks. Based upon materialoffrom © 2007 American Comer, Fundamentals Abnormal Psychology, 5e –Psychological Chapter 4 Association 26 Treatment - Cognitive Cognitive therapy can help identify possible triggers for the attacks. The trigger in an individual case could be something like A thought A situation Something subtle like a slight change in heartbeat. Therapy Goals Understanding that the panic attack is separate and independent of the trigger Awareness of the trigger(s) so it begins to lose some of its power to induce an attack. Based upon materialoffrom © 2007 American Comer, Fundamentals Abnormal Psychology, 5e –Psychological Chapter 4 Association 27 Treatment - Behavioral Behavioral components of the therapy can consist of what some clinicians call 'interoceptive exposure.' Similar to the systematic desensitization used to cure phobias, but it focuses on exposure to the actual physical sensations that someone experiences during a panic attack. Interoceptive exposure helps patients experience the symptoms of an attack (elevated heart rate, hot flashes, sweating, etc.) in a controlled setting Teachs patients that symptoms need not develop into a full-blown attack. Based upon materialoffrom © 2007 American Comer, Fundamentals Abnormal Psychology, 5e –Psychological Chapter 4 Association 28 Treatment – Behavioral 2 Behavioral therapy is also used to deal with the situational avoidance associated with panic attacks. One very effective treatment for phobias is in vivo exposure breaking a fearful situation down into small manageable steps doing them one at a time until the most difficult level is mastered. Based upon materialoffrom © 2007 American Comer, Fundamentals Abnormal Psychology, 5e –Psychological Chapter 4 Association 29 Treatment - Medication Sometimes medications may also be needed Prescriptions may include Anti-anxiety medications Antidepressants sometimes beta blockers Used to control irregular heartbeats “Absorbs” / counteracts adrenaline Based upon materialoffrom © 2007 American Comer, Fundamentals Abnormal Psychology, 5e –Psychological Chapter 4 Association 30 Treatment - Support A support group with others who suffer from panic disorder can be very helpful to some people. It can't take the place of therapy, but it can be a useful adjunct. May also be helpful to family members Based upon materialoffrom © 2007 American Comer, Fundamentals Abnormal Psychology, 5e –Psychological Chapter 4 Association 31 Treatment - Relaxation Relaxation techniques can further help someone 'flow through' an attack These techniques include breathing retraining and positive visualization Some experts have found that people with panic disorder tend to have slightly higher than average breathing rates Learning to slow breathing can help someone deal with a panic attack Mayprevent future attacks by maintaining feeling of control May prevent attacks by maintaining proper CO2 blood levels Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 32 Additional Resources Guide t o Tre a t m e nt Find a The ra pist Sha re y our St ory , Re a d Ot he rs’ in ‘St orie s of H ope ’ Ta ke a Se lf- Te st H e lp a Fa m ily Me m be r http://www.adaa.org/ International Handbook of Phobic and Anxiety Disorders in Children and Adolescents By Thomas H. Ollendick, Neville J. King, William Yule, Eds. • Chapter 13 deals with Panic Disorder • DSM-III-R Requirements for diagnosing Panic Attacks • One unexpected, full symptom attack • Four attacks or fears of an attack w/in four week period Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 33 How can I tell if it's a Panic Attack? Y e s or no? Are y ou t roubled by : Ye s No Repeat ed, unex pect ed " at t ack s" during w hich y o u suddenly are o v erco m e by int ense fear o r disco m fo rt , fo r no apparent reaso n? During t his a t t a ck , did y ou e x pe rie nce a ny of t he se sy m pt om s? Ye s No Po unding heart Ye s No Sw eat ing Ye s No Trem bling o r shak ing Ye s No Sho rt ness o f breat h Ye s No Cho k ing Ye s No Chest pain Ye s No Nausea o r abdo m inal disco m fo rt Ye s No " Jelly " legs Ye s No Diz z iness Ye s No Feelings o f unrealit y o r being det ached fro m y o urself Ye s No Fear o f dy ing Ye s No Num bness o r t ingling sensat io ns Ye s No Chills o r ho t flashes Ye s No Do y o u ex perience a fear o f places o r sit uat io ns w here get t ing help o r escape m ight be difficult , such as in a cro Ye s No Do es being unable t o t rav el w it ho ut a co m panio n t ro uble y o u? For a t le a st one m ont h follow ing a n a t t a ck , ha v e y ou: Ye s No Felt persist ent co ncern abo ut hav ing ano t her o ne? Ye s No Wo rried abo ut hav ing a heart at t ack o r go ing " craz y " ? Ye s No Changed y o ur behav io r t o acco m m o dat e t he at t ack ? Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 Slides by M. Tulloch, Ph.D. 34 Could it be something else (or something more)? Hav ing more t han one illness at t he same t ime c an make it dif f ic ult t o diagnose and t reat t he dif f erent c ondit ions. I llnesses t hat somet imes c omplic at e an anxiet y disorder inc lude depression and subst anc e abuse. Wit h t his in mind, please t ake a minut e t o answ er t he f ollow ing quest ions: Y e s No Hav e y ou experienc ed c hanges in sleeping or eat ing habit s? Y e s No Y e s No Y e s No More da y s t ha n not , do y ou fe e l: Sad or depressed? Disint erest ed in lif e? Wort hless or guilt y ? Ye s Ye s Ye s Ye s During t he la st y e a r, ha s t he use of a lcohol or drugs: Result ed in y our f ailure t o f ulf ill responsibilit ies w it h w ork, sc hool, or f amily ? Plac ed y ou in a dangerous sit uat ion, suc h as driv ing a c ar under t he inf luenc e? Got t en y ou arrest ed? Cont inued despit e c ausing problems f or y ou and/ or y our lov ed ones? No No No No http://www.adaa.org/GettingHelp/SelfHelpTests.asp Comer, Fundamentals of Abnormal Psychology, 5e – Chapter 4 35