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DETECTING and RESPONDING to signals RECEPTORS Receptors: Specialised structures capable of responding to specific stimuli by initiating signals in the nervous system or triggering the release of a hormone. Types of Receptors Chemoreceptors – These are stimulated by specific chemicals in the external and internal environment. Mechanoreceptors – These are stimulated by anything that changes the shape of the receptor. Photoreceptors – These detect light. In some animals they also detect colour and form images. Thermoreceptors – These detect external heat and cold through receptors near the surface and internal body temp. deeper in the body by receptors in the major arteries and hypothalamus. Detecting Stimuli. The intensity of a stimulus must be sufficient to reach the threshold of the receptor. This is the weakest stimulus to which the receptor can respond. Receptors then stimulate effectors to produce a response. Responding Responses in animals are based on sensory information received from all parts of the body, often requiring coordination from different parts of the body. Internal communication involved in homeostasis and regulation are carried out by the nervous and hormonal systems. The nervous system carries messages rapidly along nerve pathways. The hormonal, (ENDOCRINE), system is a slower system that releases specific chemicals into the bloodstream. RESPONDING con’t. Misalignment detectors: These are detectors that detect when a particular factor is out of line. They monitor the precise factor of the internal environment that is being controlled, eg. Oxygen level in the blood or blood temperature in the brain. Disturbance Detectors: These warn of problems before they arise. They detect the presence of external or other internal changes that may result in a change in the factor of the internal environment being controlled. Note: Disturbance and misalignment detectors allow for a more precise control of internal factors than misalignment detectors acting alone. RESPONDING con’t. Effector organs include muscles and glandular tissue. Muscle cells can be stimulated to contract or can be inhibited restricting contraction. Glands secrete biologically active substances such as hormones and enzymes. Directionality is often an important aspect of responsiveness. Some environmental stimuli, particularly light and sound the direction from which it comes is of the utmost importance. Often the direction is determined by signals from a pair of sensory organs such as eyes and ears. NERVES - NEURONS The Nervous System: The nervous 1 2 3 system is present in animals but not plants and is characterized by rapid response. It is composed of three complimentary systems: The Central Nervous System (CNS) – the Brain and Spinal Cord where most integration in the nervous system takes place. The Autonomic Nervous System – includes nerves involved in unconscious/involuntary responses. Peripheral Nervous System – includes sensory nerves and motor nerves. Types of Nerve Cells Nerve Cells: There are Three main types of nerve cells. They are: Sensory neurons – these conduct messages from the receptors to the CNS. Intermediate/Connector or Interneurons – these relay impulses from the sensory to the motor neurons. They are found in the CNS. Motor neurons – these relay messages away from the CNS to the effector organs, glands & muscles. A Typical Nerve Cell Neurons: All neurons are made up of three main parts: Cell body – contains the nucleus and the cytoplasm of the cell. Messages received by the dendrites are sent to the cell body. Axon – an elongated section of the cell body that conducts impulses away from the cell body and transmits messages to other cells. Axons vary in length and branching. Dendrite – Fine branching extensions of the neuron that conduct impulses toward the cell body and away from other cells. Electrical Insulation Myelin – rich in fats, forms an electrical insulating layer around the axon, thus increasing the speed of impulse conduction. Schwann cells – cells outside the CNS that form a tightly wrapped myelin sheath. Node of Ranvier – gaps in the myelin sheath along the axon. The sheath prevents ion flow across the neuron membrane and forces the impulse to flow from node to node. In this way impulses jump along the axon. Axon – speed of impulse travel is partly dependent on the diameter of the axon. The larger axon increases speed of conduction. (eg. squid have giant axons with very rapid conduction speeds). Nerve Impulse – Action Potential The action potential When chemicals contact the surface of a neuron, they change the balance of ions (electrically charged atoms) between the inside and outside of the cell membrane. When this change reaches a threshold level, this effect runs across the cell's membrane to the axon. When it reaches the axon, it initiates the action potential. The surface of the axon contains hundreds of thousands of miniscule mechanisms called ion channels. When the charge enters the axon, the ion channels at the base of the axon allow positively charged ions to enter the axon, changing the electrical balance between inside and outside. This causes the next group of ion channels to do the same, while other channels return positive ions to the outside, and so on all the way down the axon. Action Potential Great Website: http://outreach.mcb.harvard.edu/animations/actionpotential.swf Action Potential – movement of ions The Synapse Synapse: Neurons never touch each other. There is a gap or junction between one neuron and the next, known as a synapse. The synapse consists of the end of the axon of one neuron and the start of a dendrite of another neuron. The Axon releases a chemical called a neurotransmitter into the synapse, which diffuses across to the dendrites of the other neuron. Receptors on the dendrites combine with the neurotransmitter and trigger a nerve impulse in the next neuron Axon Mitochondria Presynaptic membrane Vesicles Neurotransmitters Receptor sites Postsynaptic membrane HORMONES – The Endocrine System The Endocrine System consists of ductless (endocrine) glands – specialised cells that secrete hormones directly into the blood stream. Hormones are specialised chemicals produced in minute amounts that are involved in the regulation of many body processes. They circulate in the bloodstream but can only be detected by specific receptors on particular cells. Most hormones only affect the production of enzymes, or structural proteins that affect growth, development, reproductive cycles and other processes in specific organs or tissues. HORMONES IN ACTION Hormonal response may be slow acting but its effects may be long lasting. The Hypothalamus gland in the brain is the main control centre that regulates hormones by sending nerve or hormonal messages to the Pituitary gland. The Pituitary gland, in turn passes “messages” via hormones to target tissues around the body. The Endocrine Glands Comparison of Hormone Types Type Relative Size Movement Examples Fatty-acid hormones Small Lipid-soluble, so they pass directly through plasma membranes. Steroid hormones: Testosterone , oestrogen, progesterone Amino-acid hormones Larger Water-soluble, so they bind to receptors on plasma membranes. This activates the second messenger mechanism, cyclic AMP, which causes the change within the cell. Insulin, glucagon, adrenaline, thyroxine, oxytocin, ADH (antidiuretic hormone, growth hormone Hormones in Action Hormone Neural or hormonal stimulation Receptor Hormone fuses to specific receptors on target cells Carried by bloodstream around the body Target Cell Endocrine gland Hormone secreted Response Hormone Hormones con’t. Pheromones are chemical signals released outside the body. They target organisms of the same species and are most commonly used to attract mates or mark territory. Comparing The Nervous And Endocrine Systems Nervous System Hormonal System Type of message Electrochemical impulse Chemical messenger Speed of message Rapid Slow Transmission Nerves / Neurons Bloodstream Duration of response Short Long lasting Target Very specific in target neurons, muscles or glands More general, to target tissues or organs in the body REGULATION IN PLANTS Plants are able to adjust their growth and development in response to the environment. When a plant responds to an external stimulus the plant exhibits a TROPISM. Growth towards a stimulus is called a Positive Tropism. Growth away from the stimulus is called a Negative Tropism. Stimulus Tropism Light Gravity Touch Water Phototropism Geotropism Thigmotropism Hydrotropism Plants: Sensing and Responding Stimuli Plants do not monitor their internal environment, as do animals. They are however sensitive to a number of environmental factors, both physical and chemical factors. Physical Factors: include direction and wavelength of light, day/night length (photoperiod), gravity, temperature and touch. Chemical Factors: include water, carbon dioxide and specific chemicals, for example ethylene gas (which ripens fruit). Directionality is often important in plant sensing. Eg. Shoots growing towards light, Roots responding to gravity by growing down. Responding Growth in plants is triggered by environmental factors. When the direction of the growth is related to the direction from which the stimulus comes the response is called a tropism. See previous lesson for various Tropisms. Summary: Plant Hormonal Responses Compared To Animals Hormonal responses in plants are relatively simple. Plants have no endocrine system like animals. Hormone secreting cells are not organised into specialised glands. Plant hormones are generally produced by cells receiving appropriate stimuli. Plant hormonal responses are much slower. Plant hormones are distributed through: 1. From cell to cell 2. Transport pathways – usually the phloem 3. Even through the air. FLOWERING Plants flower, develop fruit and become dormant at the most favourable times of the year. These are controlled by the daily light length, or PHOTOPERIOD. A response to the photoperiod is called a photoperiodism. It is the night-length that stimulates flowering. Short-day plants: long nights. Produce flowers when the photoperiod is less than a critical value. So flowering is prevented if the hours of daylight are too long. These plants usually flower in late summer, autumn or winter. Long-day plants: short nights. Will not flower until the hours of daylight exceed a threshold value. They tend to flower in late spring or early summer. In day neutral plants, the length of the photoperiod is unimportant. A signal from the leaves, possibly a hormone called florigen, causes development of buds. DORMANCY & VERNALISATION DORMANCY Some plants become dormant prior to winter. Lower Temps and shortening days trigger changes that involve loss of chlorophyll from leaves and withdrawal of nutrients from leaves into stems and roots. Abscisic acid is largely responsible for bud dormancy. Dormancy is broken by substantial rainfall, intense heat (fire) to break seed coat, extended exposure to cold or light or chemicals found in the digestive tracts of animals. VERNALISATION Some plants require exposure to cold before they can complete their life cycle. Vernalisation is the period of winter cold that stimulates flowering in many plants.