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Transcript
Spinal Cord and Nerves
The Nervous System
 Coordinates the activity of muscles, organs,
senses, and actions
 Made up of nervous tissue
 Has 3 main functions:



1. Receives sensory Input
2. Integration
3. Dictates motor output
Divisions of the Nervous System
 Central Nervous System (CNS)
 Brain and spinal cord
 Interprets incoming sensory signals
 Dictates motor responses
 Peripheral Nervous System (PNS)
 Ganglia
 Nerves
 Cranial nerves and spinal nerves
 Communication between regions of
body and CNS
Review of Nervous Cells
 Neuron
 Cell body
 Dendrite
 Axon
 Myelin Sheath
 Neuroglia
 Interneuron
 Reflex Arc
 Synapse
Organization of a Nerve
 Endoneurium
 Surrounds each axon (nerve fiber)
 Myelinated and Unmyelinated
axons
 Motor and Sensory nerve fibers
 Loose CT
 Perineurium
 Bundles axons into fascicles
 CT
 Epineurium
 Bundles fascicles into a nerve
 Fibrous CT
 CT layers contain blood vessels
Types of Nerve Signals/Fibers
 Sensory (afferent)


Picked up by sensory receptors thru body
Carried by nerve fibers of PNS into CNS
 Motor (efferent)



Carried away from the CNS by nerve fibers
into PNS
Innervate muscles and glands
Causes these organs to contract or secrete
 Remember: SAME
Sensory and Motor Signals/Fibers
 Somatic sensory
Body senses
 touch, pressure, temperature, vibration of body, muscles
stretching, balance
 Visceral sensory
 Organ senses
 Stretch, pain, temperature in organs
 (eg) nausea, hunger, cramps
 Somatic motor
 Body movement
 Voluntary contraction of skeletal muscles
 Visceral motor
 Organ movement
 Contraction of smooth muscle, glands
 = Autonomic Nervous System (involuntary)

CNS – Spinal Cord
 Runs through vertebral canal of the vertebral




column
Protected by bone, meninges, and
cerebrospinal fluid
Spinal cord made of a core of gray matter
surrounded by white matter
31 pairs of spinal nerves branch off spinal cord
through intervertebral foramen
Functions in many ways:



Involved in sensory and motor
innervation of body inferior to the head
(through spinal nerves)
Provides a 2-way conduction pathway
for signals between body and brain
Major center for reflexes
Spinal Cord Segments
Meninges of Spinal Cord
 Dura mater (superficial)
Spinal dural sheath
 Does not attach to bone
 Epidural space
 Fat and veins
 Between dura mater and
vertebra
 Subdural space


Between dura mater and
arachnoid
Meninges of Spinal Cord
 Arachnoid mater (middle)
Impermeable layer =
barrier
 Raised off pia mater by
rootlets
 Subarachnoid space
 Between arachnoid and
pia mater
 Contains CSF
 Pia mater (deep)
 Highly vascular
 Adheres to brain/spinal
cord tissue

Regions of Spinal Cord
 Cervical
 Thoracic
 Lumbar
 Sacral
 Coccygeal
 Cervical + Lumbar
enlargements
 Cauda equina
 Conus medullaris
 Filum terminale
Gray Matter
 Consists of neuron cell
bodies, unmyelinated
axons, dendrites, and
neuroglia
 Shaped like an “H”


Gray commissure
(crossbar)
Central canal
 Posterior horns
 Anterior horns
Gray Matter
 Posterior horns


Consist of interneurons that transmit in from outside spinal cord into it
Dorsal root contain sensory fibers


Somatic Sensory (SS)
Visceral Sensory (VS)
Dorsal root ganglia - swelling in dorsal root that these interneurons pass
through
 Anterior horns
 Cell bodies of motor neurons send info out of spinal cord to muscles and
glands
 Ventral Root contains Motor Fibers



Visceral Motor
Somatic Motor
White Matter
 Surrounds gray matter
 Composed of myelinated
and unmyelinated axons
 Divided into white
columns (funiculi)



Posterior funiculus
Anterior funiculus
Lateral funiculus
 Allow for communication
between


Parts of the spinal cord
Spinal cord and brain
White Matter
 3 types of nerve fibers:

Ascending



Descending




Carry sensory info from sensory neurons of body to brain
touch, pressure, pain, temperature
Carry motor instructions from brain to spinal cord
Contraction of muscles and secretion of glands
control precise, skilled movement = writing, maintain balance,
create movement
Commissural

Cross from one side of cord to the other
Spinal Nerves (31 Pairs)
 Part of the PNS (Somatic)
 Lie in intervertebral foramina
Send lateral branches to
body
 Named according to their point
of issue from the vertebral
column
 8 pairs of cervical spinal
nerves; C1-C8
 12 pairs of thoracic spinal
nerves; T1-T12
 5 pairs of lumbar spinal
nerves; L1-L5
 5 pairs of sacral spinal
nerves; S1-S5
 1 pair of coccygeal spinal
nerves; C01

Spinal Nerves
 Each spinal nerve connected to
spinal cord via dorsal (sensory)
and ventral (motor) root
 Spinal nerves branch into
dorsal ramus and ventral ramus


Ventral ramus
 Connects to rami
communicates, which then
lead to sympathetic chain
ganglia
 Supply anterior and lateral
regions of the neck, trunk,
and limbs
Dorsal ramus
 Supply the dorsum of the
neck and trunk (back)
The Big Picture
 Just lateral to
intervertebral
foramen, each
spinal nerve then
splits in 2


Dorsal Rami
Ventral Rami
 Contain BOTH
Sensory and
Motor fibers!!
Autonomic Nervous System
 Visceral Motor Function
 Not easily controlled by will
 Get nervous and sweat
 Innervate smooth muscle, cardiac muscle,
glands
 Regulate visceral function

Heart rate, blood pressure, digestion, urination
 Has 2 divisions:
 Parasympathetic
 Sympathetic
ANS
 Parasympathetic
 Enables body to
unwind and calm down
 Most active when body
at rest
 Routine maintenance
functions
 Craniosacral division
 Fibers emerge from
brain and sacral
spinal cord
 Sympathetic
 “fight or flight”
 Mobilizes the body
during extreme
situations
 Becomes active when
extra metabolic effort
needed
 Thoracolumbar
division
 Fibers arise from
thoracic and lumbar
parts of spinal cord
Somatic Nervous System
 Innervates skeletal muscle
 Neurons runs from CNS directly to muscle
 Consists of single neuron plus skeletal
muscle cells
 Voluntary control

Running, moving limbs, typing on a
computer!